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Steve Quake

👤 Person
149 total appearances

Appearances Over Time

Podcast Appearances

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

Thanks, Eric.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

It's great to be here.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

We did.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

We had a meeting at CZI to bring community members together from many different parts of the community, from computer science to bioinformatics, AI experts, biologists who don't trust any of this.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

We wanted to have some real contrarians in the mix as well.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

And have them have a conversation together about, is there an opportunity here?

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

What's the shape of it?

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

What's realistic to expect?

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

And that was sort of the genesis of the article.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

Yeah, Charlotte, you want me to take the first shot at that?

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

Okay.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

So, Eric, it is a bold claim, and we have a really bold ambition here.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

We view that over the course of a decade, AI is going to provide the ability to

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

make a transformative computational tool for biology.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

Right now, cell biology is 90% experimental and 10% computational, roughly speaking.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

And you've got to do just all kinds of tedious, expensive, challenging lab work to get to the answer.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

And I don't think AI is going to replace that, but it can invert the ratio.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

So within 10 years, I think we can get to biology being 90% computational and 10% experimental.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

And the goal of the virtual cell is to build a tool that'll do that.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

Yes.

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