Tim Friede
👤 PersonAppearances Over Time
Podcast Appearances
He recovered, got more careful, and he kept on going. Then at some point, he was like, hey, could my immunity to this swirl of toxins provide some kind of roadmap to making a broad kind of antivenom?
He recovered, got more careful, and he kept on going. Then at some point, he was like, hey, could my immunity to this swirl of toxins provide some kind of roadmap to making a broad kind of antivenom?
He recovered, got more careful, and he kept on going. Then at some point, he was like, hey, could my immunity to this swirl of toxins provide some kind of roadmap to making a broad kind of antivenom?
Right. So usually when the human body encounters a foreign substance, whether it's a poison or a parasite or virus, it'll trigger some kind of immune response, which involves the production of antibodies, specialized proteins that specifically recognize that substance, bind to it and neutralize or destroy it.
Right. So usually when the human body encounters a foreign substance, whether it's a poison or a parasite or virus, it'll trigger some kind of immune response, which involves the production of antibodies, specialized proteins that specifically recognize that substance, bind to it and neutralize or destroy it.
Right. So usually when the human body encounters a foreign substance, whether it's a poison or a parasite or virus, it'll trigger some kind of immune response, which involves the production of antibodies, specialized proteins that specifically recognize that substance, bind to it and neutralize or destroy it.
Yep, right.
Yep, right.
Yep, right.
Exactly. So pit viper antivenom, for example, is made from antibodies that already recognize pit viper venom and know how to handle it. And those antibodies can be used as a treatment. Gotcha. But here's the thing about existing antivenoms that might be administered. The antibodies that they contain aren't produced by human immune systems.
Exactly. So pit viper antivenom, for example, is made from antibodies that already recognize pit viper venom and know how to handle it. And those antibodies can be used as a treatment. Gotcha. But here's the thing about existing antivenoms that might be administered. The antibodies that they contain aren't produced by human immune systems.
Exactly. So pit viper antivenom, for example, is made from antibodies that already recognize pit viper venom and know how to handle it. And those antibodies can be used as a treatment. Gotcha. But here's the thing about existing antivenoms that might be administered. The antibodies that they contain aren't produced by human immune systems.
For decades, they've come from animals like horses that have been injected repeatedly with small amounts of venom. Wow. But this guy named Jacob Glanville, he's the CEO of a biotech company called Centivax. He wondered about a different approach, making antivenoms from antibodies produced by humans. So he started calling around.
For decades, they've come from animals like horses that have been injected repeatedly with small amounts of venom. Wow. But this guy named Jacob Glanville, he's the CEO of a biotech company called Centivax. He wondered about a different approach, making antivenoms from antibodies produced by humans. So he started calling around.
For decades, they've come from animals like horses that have been injected repeatedly with small amounts of venom. Wow. But this guy named Jacob Glanville, he's the CEO of a biotech company called Centivax. He wondered about a different approach, making antivenoms from antibodies produced by humans. So he started calling around.
Yes. And then Jacob read about Tim.
Yes. And then Jacob read about Tim.
Yes. And then Jacob read about Tim.