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Venki Ramakrishnan

๐Ÿ‘ค Speaker
476 total appearances

Appearances Over Time

Podcast Appearances

Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas
291 | Venki Ramakrishnan on the Biology of Death and Aging

Another possibility is that as we get older, short-term memory is one of the things to go. And maybe the creative act requires holding disparate facts in your head in an attempt to synthesize some new thing. And if we're not able to hold them while we're trying to synthesize it, that makes creativity harder. So there are a number of explanations.

Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas
291 | Venki Ramakrishnan on the Biology of Death and Aging

Another possibility is that as we get older, short-term memory is one of the things to go. And maybe the creative act requires holding disparate facts in your head in an attempt to synthesize some new thing. And if we're not able to hold them while we're trying to synthesize it, that makes creativity harder. So there are a number of explanations.

Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas
291 | Venki Ramakrishnan on the Biology of Death and Aging

And I also think if you look at social change, things like that, it's often driven by the young. And there's a whole question of intergenerational fairness. If old people just hang on to power positions, et cetera, there's this problem of turnover. And we in academia are only too well aware of this. And so I think... For all sorts of reasons, it's problematic.

Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas
291 | Venki Ramakrishnan on the Biology of Death and Aging

And I also think if you look at social change, things like that, it's often driven by the young. And there's a whole question of intergenerational fairness. If old people just hang on to power positions, et cetera, there's this problem of turnover. And we in academia are only too well aware of this. And so I think... For all sorts of reasons, it's problematic.

Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas
291 | Venki Ramakrishnan on the Biology of Death and Aging

But of course, the flip side, as someone pushed back against me, was that, look, 150 years ago, we were living half as long as we do now on average. Of course, the oldest people were still living quite long, but on average. And now we're all living about twice as long on average. Do you think we should go back to the older time because there was more regeneration, faster regeneration?

Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas
291 | Venki Ramakrishnan on the Biology of Death and Aging

But of course, the flip side, as someone pushed back against me, was that, look, 150 years ago, we were living half as long as we do now on average. Of course, the oldest people were still living quite long, but on average. And now we're all living about twice as long on average. Do you think we should go back to the older time because there was more regeneration, faster regeneration?

Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas
291 | Venki Ramakrishnan on the Biology of Death and Aging

Or would you want to go back? And of course, none of us would, right? And tomorrow, if somebody came to you with a pill and said, look, this is the result of anti-aging research. It's going to give you 10 extra years of healthy life. Nobody wants to live unhealthy, but say 10 extra years of healthy life. Most of us would take it. And that's the paradox.

Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas
291 | Venki Ramakrishnan on the Biology of Death and Aging

Or would you want to go back? And of course, none of us would, right? And tomorrow, if somebody came to you with a pill and said, look, this is the result of anti-aging research. It's going to give you 10 extra years of healthy life. Nobody wants to live unhealthy, but say 10 extra years of healthy life. Most of us would take it. And that's the paradox.

Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas
291 | Venki Ramakrishnan on the Biology of Death and Aging

We as individuals don't necessarily do what's best for we as a species or as a group. We haven't evolved that way. And this is the problem behind all sorts of social problems, including climate change. We're unwilling to do the things individually that we know might help us as a society.

Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas
291 | Venki Ramakrishnan on the Biology of Death and Aging

We as individuals don't necessarily do what's best for we as a species or as a group. We haven't evolved that way. And this is the problem behind all sorts of social problems, including climate change. We're unwilling to do the things individually that we know might help us as a society.

Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas
291 | Venki Ramakrishnan on the Biology of Death and Aging

Absolutely. I'll tell you one thing that I didn't say apart from the trio. There are other things that help with aging, and that is avoiding social isolation. It turns out reduces mortality. But having a sense of purpose also reduces mortality. That, to me, was a bit surprising. But in hindsight, perhaps not so surprising because it gives you that will to go out and do things.

Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas
291 | Venki Ramakrishnan on the Biology of Death and Aging

Absolutely. I'll tell you one thing that I didn't say apart from the trio. There are other things that help with aging, and that is avoiding social isolation. It turns out reduces mortality. But having a sense of purpose also reduces mortality. That, to me, was a bit surprising. But in hindsight, perhaps not so surprising because it gives you that will to go out and do things.

Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas
291 | Venki Ramakrishnan on the Biology of Death and Aging

So, you know, one of the purposes in your life is your podcast. And it definitely, you know, thinking about it, thinking about what new topics to discuss and whom to invite. You know, those are all things that are going to keep you young.

Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas
291 | Venki Ramakrishnan on the Biology of Death and Aging

So, you know, one of the purposes in your life is your podcast. And it definitely, you know, thinking about it, thinking about what new topics to discuss and whom to invite. You know, those are all things that are going to keep you young.

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