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Vinod Khosla

๐Ÿ‘ค Speaker
228 total appearances

Appearances Over Time

Podcast Appearances

All-In with Chamath, Jason, Sacks & Friedberg
Hurricane fallout, AlphaFold, Google breakup, Trump surge, VC giveback, TikTok survey

In the early 1900s, the city of Phoenix, Arizona averaged five days a year of temperatures of 110 degrees or warmer. By the 2010s, Phoenix averaged, during the 2010s, 27 days a year where the temperature was 110 or higher. Since 2021, Phoenix averaged- 100 plus days. 42 days. And in 2024, it's been 70 days so far this year that the temperature is over 110.

All-In with Chamath, Jason, Sacks & Friedberg
Hurricane fallout, AlphaFold, Google breakup, Trump surge, VC giveback, TikTok survey

In the early 1900s, the city of Phoenix, Arizona averaged five days a year of temperatures of 110 degrees or warmer. By the 2010s, Phoenix averaged, during the 2010s, 27 days a year where the temperature was 110 or higher. Since 2021, Phoenix averaged- 100 plus days. 42 days. And in 2024, it's been 70 days so far this year that the temperature is over 110.

All-In with Chamath, Jason, Sacks & Friedberg
Hurricane fallout, AlphaFold, Google breakup, Trump surge, VC giveback, TikTok survey

So this is affecting, and so there's increased risks in California with wildfires, increased risk with hurricane. There are a lot of these factors, and I have friends that work in reinsurance and in the insurance markets.

All-In with Chamath, Jason, Sacks & Friedberg
Hurricane fallout, AlphaFold, Google breakup, Trump surge, VC giveback, TikTok survey

So this is affecting, and so there's increased risks in California with wildfires, increased risk with hurricane. There are a lot of these factors, and I have friends that work in reinsurance and in the insurance markets.

All-In with Chamath, Jason, Sacks & Friedberg
Hurricane fallout, AlphaFold, Google breakup, Trump surge, VC giveback, TikTok survey

Jason, it's called a mutual. And those are like a good chunk of the industry are mutuals where it's the shareholders are the members and they all share the risk and the ownership.

All-In with Chamath, Jason, Sacks & Friedberg
Hurricane fallout, AlphaFold, Google breakup, Trump surge, VC giveback, TikTok survey

Jason, it's called a mutual. And those are like a good chunk of the industry are mutuals where it's the shareholders are the members and they all share the risk and the ownership.

All-In with Chamath, Jason, Sacks & Friedberg
Hurricane fallout, AlphaFold, Google breakup, Trump surge, VC giveback, TikTok survey

So if you do proper underwriting, what's happened in the last couple of years is all the reinsurance companies and all the insurance companies have had to re underwrite the rates that they charge for insurance, because the frequency of a disaster has gone up. And the new price that they should be charging is so high, it doesn't matter how the capital structure is set up.

All-In with Chamath, Jason, Sacks & Friedberg
Hurricane fallout, AlphaFold, Google breakup, Trump surge, VC giveback, TikTok survey

So if you do proper underwriting, what's happened in the last couple of years is all the reinsurance companies and all the insurance companies have had to re underwrite the rates that they charge for insurance, because the frequency of a disaster has gone up. And the new price that they should be charging is so high, it doesn't matter how the capital structure is set up.

All-In with Chamath, Jason, Sacks & Friedberg
Hurricane fallout, AlphaFold, Google breakup, Trump surge, VC giveback, TikTok survey

It's simply, there's, there's one big event that's going to cause a big wipeout for a large number.

All-In with Chamath, Jason, Sacks & Friedberg
Hurricane fallout, AlphaFold, Google breakup, Trump surge, VC giveback, TikTok survey

It's simply, there's, there's one big event that's going to cause a big wipeout for a large number.

All-In with Chamath, Jason, Sacks & Friedberg
Hurricane fallout, AlphaFold, Google breakup, Trump surge, VC giveback, TikTok survey

That's right.

All-In with Chamath, Jason, Sacks & Friedberg
Hurricane fallout, AlphaFold, Google breakup, Trump surge, VC giveback, TikTok survey

That's right.

All-In with Chamath, Jason, Sacks & Friedberg
Hurricane fallout, AlphaFold, Google breakup, Trump surge, VC giveback, TikTok survey

I think they're different, but Florida is like, I mean, I don't know how you do the math on, I just don't know what you do on a trillion dollars of real estate value with half a trillion of mortgages. when you have real exposure on loss more frequently than one in 100 years, to your point, they need to be repriced.

All-In with Chamath, Jason, Sacks & Friedberg
Hurricane fallout, AlphaFold, Google breakup, Trump surge, VC giveback, TikTok survey

I think they're different, but Florida is like, I mean, I don't know how you do the math on, I just don't know what you do on a trillion dollars of real estate value with half a trillion of mortgages. when you have real exposure on loss more frequently than one in 100 years, to your point, they need to be repriced.

All-In with Chamath, Jason, Sacks & Friedberg
Hurricane fallout, AlphaFold, Google breakup, Trump surge, VC giveback, TikTok survey

And how do you reprice those homes in the significant level that they need to be repriced without causing massive economic and social consequence? That's what's kind of, I think, challenging me in thinking about what's the path here.

All-In with Chamath, Jason, Sacks & Friedberg
Hurricane fallout, AlphaFold, Google breakup, Trump surge, VC giveback, TikTok survey

And how do you reprice those homes in the significant level that they need to be repriced without causing massive economic and social consequence? That's what's kind of, I think, challenging me in thinking about what's the path here.

All-In with Chamath, Jason, Sacks & Friedberg
Hurricane fallout, AlphaFold, Google breakup, Trump surge, VC giveback, TikTok survey

Did we predict that they would win the Nobel Prize at the time?

All-In with Chamath, Jason, Sacks & Friedberg
Hurricane fallout, AlphaFold, Google breakup, Trump surge, VC giveback, TikTok survey

Did we predict that they would win the Nobel Prize at the time?

All-In with Chamath, Jason, Sacks & Friedberg
Hurricane fallout, AlphaFold, Google breakup, Trump surge, VC giveback, TikTok survey

There's been a long challenge in biochemistry on understanding or predicting or visualizing the three-dimensional structure of proteins. Because remember, proteins are produced by long chains of amino acids. And those amino acids are kind of create like a bead, beaded necklace. And then the whole necklace collapses on itself in a very specific way.

All-In with Chamath, Jason, Sacks & Friedberg
Hurricane fallout, AlphaFold, Google breakup, Trump surge, VC giveback, TikTok survey

There's been a long challenge in biochemistry on understanding or predicting or visualizing the three-dimensional structure of proteins. Because remember, proteins are produced by long chains of amino acids. And those amino acids are kind of create like a bead, beaded necklace. And then the whole necklace collapses on itself in a very specific way.