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80,000 Hours Podcast

#171 – Alison Young on how top labs have jeopardised public health with repeated biosafety failures

09 Nov 2023

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"Rare events can still cause catastrophic accidents. The concern that has been raised by experts going back over time, is that really, the more of these experiments, the more labs, the more opportunities there are for a rare event to occur — that the right pathogen is involved and infects somebody in one of these labs, or is released in some way from these labs. And what I chronicle in Pandora's Gamble is that there have been these previous outbreaks that have been associated with various kinds of lab accidents. So this is not a theoretical thing that can happen: it has happened in the past." — Alison YoungIn today’s episode, host Luisa Rodriguez interviews award-winning investigative journalist Alison Young on the surprising frequency of lab leaks and what needs to be done to prevent them in the future.Links to learn more, summary, and full transcript.They cover:The most egregious biosafety mistakes made by the CDC, and how Alison uncovered them through her investigative reportingThe Dugway life science test facility case, where live anthrax was accidentally sent to labs across the US and several other countries over a period of many yearsThe time the Soviets had a major anthrax leak, and then hid it for over a decadeThe 1977 influenza pandemic caused by vaccine trial gone wrong in ChinaThe last death from smallpox, caused not by the virus spreading in the wild, but by a lab leak in the UK Ways we could get more reliable oversight and accountability for these labsAnd the investigative work Alison’s most proud ofChapters:Cold open (00:00:00)Luisa's intro (00:01:13)Investigating leaks at the CDC (00:05:16)High-profile CDC accidents (00:16:13)Dugway live anthrax accidents (00:32:08)Soviet anthrax leak (00:44:41)The 1977 influenza pandemic (00:53:43)The last death from smallpox (00:59:27)How common are lab leaks? (01:09:05)Improving the regulation of dangerous biological research (01:18:36)Potential solutions (01:34:55)The investigative work Alison’s most proud of (01:40:33)Producer and editor: Keiran HarrisAudio Engineering Lead: Ben CordellTechnical editing: Simon Monsour and Milo McGuireAdditional content editing: Katy Moore and Luisa RodriguezTranscriptions: Katy Moore

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