Age Well with Dr Sophie Shotter
Episodes
Why spermidine is the longevity supplement going mainstream in 2026 - with Primeadine’s Leslie Kenny
09 Dec 2025
Contributed by Lukas
Leslie’s story | the birth of Oxford Healthspan | spermidine and the immune system | the latest data on spermidine and cancer | spermidine and ferti...
Why 2025 saw a blepharoplasty boom - with Dr Elizabeth Hawkes
02 Dec 2025
Contributed by Lukas
Bags under the eyes | dark circles | upper and lower blepharoplasty | menopause and dry eyes | recommended eye creams | micellar water | eye health su...
Ayahuasca, psychedelics, and Dr Joe Tafur's journey from trained doctor to the Peruvian Amazon
25 Nov 2025
Contributed by Lukas
Dr Joe’s journey from medic to the Peruvian Amazon | An ayahuasca explainer | ayahuasca’s unique qualities | the nervous system and immune system ...
Ashwagandha. Is it the ultimate stress fixer + the facts behind the Danish ban
18 Nov 2025
Contributed by Lukas
The benefits | how ashwagandha reduces stress | people’s wildly different responses | Why has Denmark banned it and is the ban justified? | How to t...
Sarah Bradden’s incredible story of recovery – and how this led to The Bradden Method
11 Nov 2025
Contributed by Lukas
From misdiagnosis to a life-changing shift | the Bradden Method explained | Sarah’s tool kit | light therapy | activated oxygen | intuition | workin...
What's in my kit - from make-up artist Emma Rankin
04 Nov 2025
Contributed by Lukas
Emma’s break into the industry | where Emma buys | primers | dark circles and puffy eyes | foundation | concealer | blush and bronzer | mascara, ey...
How I recovered from long COVID - Dr Tam Lewis
28 Oct 2025
Contributed by Lukas
Personalised health testing | thyroid-related issues | stress and adrenal fatigue | cholesterol | how to calm the nervous system | ashwagandha | Tam’...
Dr Nichola Conlon on ageing well - and figuring out our biological age
21 Oct 2025
Contributed by Lukas
Nichola’s approach and routine | health testing and tracking | the MTHFR gene mutation | Nuchido Time + and new data on sleep | Nichola’s suppleme...
The truth about low testosterone and why so many men need TRT - with Dr Jeff Foster
14 Oct 2025
Contributed by Lukas
Signs of testosterone deficiency | the issues with testing | delivery systems | are there risks with testosterone therapy? | men and thyroid issues | ...
What we now know about eggs, sperm, and fertility (new data, new ideas)
07 Oct 2025
Contributed by Lukas
Why people struggle to conceive | new data on what helps | fertility supplements - is there such a thing? | egg quality | endocrine disruptors | the l...
Grounding sheets (and how an insomniac got their "best ever night's sleep")
30 Sep 2025
Contributed by Lukas
What is grounding? | grounding sheets - an explainer | an interesting experience from an insomniac | the latest data | forest bathing | natural ground...
A chat with cult facialist and skincare visionary... Sarah Chapman
23 Sep 2025
Contributed by Lukas
Peptides | exosomes | the skin microbiome / exfoliation | Sarah’s range | Sarah’s recommendations - and routine
Metformin + ivermectin + rapamycin (etc) << a ‘longevity’ drugs explainer
16 Sep 2025
Contributed by Lukas
Metformin | rapamycin | ivermectin | NMN | NAD | resveratrol | spermidine
How to radically improve your digital nutrition - with Dr Kaitlyn Regehr
09 Sep 2025
Contributed by Lukas
Screen addiction | sharenting | the attention economy | algorithms | cookies / privacy | tools for digital nutrition
NEW data / thinking on insulin – from Alzheimer’s to PCOS - Prof Ben Bikman
02 Sep 2025
Contributed by Lukas
Insulin for beginners | disease states connected to insulin resistance | metabolism and the rise in breast cancer | PCOS | cholesterol | ED | weight l...
Viagra + Cialis + NEW options for female libido (and does Viagra lower the risk of Alzheimer’s?)
26 Aug 2025
Contributed by Lukas
Viagra and Cialis – an explainer | longevity research inc. Alzheimer's | ED | is female Viagra a thing? | data on female desire | libido supplements...
Dr Stacy Sims - the world's leading voice on why women need to exercise differently to men
19 Aug 2025
Contributed by Lukas
Women are not small men (the data) | strength training | technique | body shapes | exercise + stress | pelvic floor | fasting | cold plunge | protein ...
Why the science world is getting *so* excited about post-biotics (short explainer)
12 Aug 2025
Contributed by Lukas
The difference between probiotics and prebiotics | postbiotics explainer | how postbiotics might fight disease | are prebiotics better than pro? | sup...
Forget everything you know about taking magnesium and other mineral supp's - and meet Caroline Alan
05 Aug 2025
Contributed by Lukas
Caroline’s story | the chronic health issues associated with mineral deficiency | what are plant-based minerals? | mineral deficiency signs and test...
Ozempic and other weight loss drugs - the headlines, the concerns, and *everything* you need to know
29 Jul 2025
Contributed by Lukas
A quick 101 | the side effects and those news headlines | the longevity link | the wider concerns | slimming pills | Ozempic and fertility | muscle lo...
Chemicals in personal care and cleaning products. Should we be worried?
22 Jul 2025
Contributed by Lukas
Chemicals in cleaning products | endocrine disruptors | personal care | non toxic brands | genetically modified enzymes | perfumes | deodorant | SPF |...
All things breast surgery (and is breast implant illness a thing?) - Nora Nugent
15 Jul 2025
Contributed by Lukas
Silicone or saline | Smooth or textured | Teardrop or round | Under or over | new technologies | risks and issues | uplifts, reductions, removal | bre...
Meta Cell Technology (MCT): is this the biggest skincare breakthrough in years?
08 Jul 2025
Contributed by Lukas
What are exosomes? | exosome therapy | exosomes in skincare | PRP therapy | exosome therapy v PRP | biohacking the skin with meta cell technology
Signs of thyroid issues + an iodine explainer + the menopause link
01 Jul 2025
Contributed by Lukas
The thyroid and iodine link | hypo / hyper thyroidism | iodine deficiency | Conventional treatments | the alternatives | stress | exercise | menopause
Product favourites w/ journalist and Beauty Director Alessandra Steinherr
24 Jun 2025
Contributed by Lukas
Alex’s routine | peptides | tweakments | Hair | fragrance | foundations and mascara | lessons as a founder | supplements | favourite spa | bedtime ...
A 20 minute creatine explainer inc. new findings on mental health
17 Jun 2025
Contributed by Lukas
A quick 101 | the benefits | mental health | women and creatine | new data on Alzheimer's | how to take it | loading | cycling | Side effects – the ...
New data on snacking + protein + sweeteners + early colorectal cancer (and more) – ZOE's Prof Sarah Berry
10 Jun 2025
Contributed by Lukas
How food impacts the menopause | weight loss jabs | the battles around non dairy | supplements | cholesterol | the process of ultra processed food | Z...
The ultimate guide to happy, healthy hair – Tom Smith
03 Jun 2025
Contributed by Lukas
Managing expectations with colour | grey hair | hair dye ingredients | Tom’s brand favourites | hair loss | heat protection | scalp care | biohackin...
How to build a skincare brand that blends science with soul - Annee de Mamiel
27 May 2025
Contributed by Lukas
Annee’s approach | the major metabolic pathways and their effects on the skin | Annee’s facials | growing the brand | the skincare range | Annee’...
A new approach to the pelvic floor + a protein powder designed for women – Rachel Prince
20 May 2025
Contributed by Lukas
Prolapse and diastasis recti | how to do a pelvic floor exercise correctly | exercise | LØUCO and protein powders | creatine | Rachel’s approach to...
How I recovered from PCOS + an autoimmune disease – and became pregnant - Liberty Mills
13 May 2025
Contributed by Lukas
Liberty’s story | Trying to get pregnant | the power of bone broth | filtering water | choosing the right exercise so the body isn’t stressed | en...
The Magic of Mushrooms – Part 2 – Andrew Salter (Dirtea)
06 May 2025
Contributed by Lukas
The cultural shift from alcohol | building a brand | having a brand identity versus piggybacking trends | Andrew’s routine | lion’s mane and ADHD ...
Lifting weights is the panacea of longevity - Claire Sanderson
29 Apr 2025
Contributed by Lukas
Claires routine | strength training | kit | fitness trackers / wearables | skincare and ageing well | spas | mental health | thoughts on wellness
In Paris they appreciate a midlife woman – Lisa Armstrong OBE
22 Apr 2025
Contributed by Lukas
Getting organised | Lisa’s new eating plan | Lisa’s favourite facialist | fashion talk – inc fashion on a budget | alternative therapies | the u...
The Beauty Triangle, entrepreneur life - and an incredible acupuncture story - Francesca Ogiermann-White
15 Apr 2025
Contributed by Lukas
The Beauty Triangle | Fran’s routine | thoughts on treatments, tweakments, surgery - and wellness | PCOS and getting back into a menstrual cycle | s...
Navigating a new phase of womanhood - Trish Halpin
08 Apr 2025
Contributed by Lukas
This new phase of being a mid-life woman | managing career shifts | managing time | daily rituals | prioritising bone health | getting good sleep | pr...
How to reinvent when life throws a curve ball - Jo Elvin
01 Apr 2025
Contributed by Lukas
Career identity | building a podcast | fame and meeting celebs | friendships | k-pop | skin | medical spas | bathroom products | peloton | functional ...
The Magic of Mushrooms - Part 1 - Tom Baxter (Bristol Fungarium)
25 Mar 2025
Contributed by Lukas
Tom’s story | lion's mane and brain health | reishi and the nervous system / inflammation | turkey tail and cancer | cordyceps and sex drive | data ...
The Priorities Method - and how to figure out what it is you really want - Lily Silverton
18 Mar 2025
Contributed by Lukas
Priorities | busyness | hybrid careers | starting up a business | Lily’s routine | good habits | a lifetime of yoga | inbox management and managing ...
How we're navigating mid-life - Annabel Rivkin and Emilie McMeekan
11 Mar 2025
Contributed by Lukas
Anxiety | alcohol | infidelity | friendships | ageing | skincare | supplements | brain health | inspiring women | the ultimate day in London
Unpacking the buzz around 'deep plane' - a more natural approach to face lifts - Marc Pacifico
04 Mar 2025
Contributed by Lukas
The new deep plane technique | a typical patient | achieving a natural facelift result | self esteem | how to deal with the neck | the reality of havi...
Over 35 yrs in beauty... this is my routine and my must-have products - Nadine Baggott
25 Feb 2025
Contributed by Lukas
Desert island skincare | Nadine’s routine | Treatments and tweakments | Surgery and ‘super surgeons' | beauty gadgets | Supplements | Fragrances |...
I've seen data that this is transforming women's vaginal health - Dr Zoe Williams
18 Feb 2025
Contributed by Lukas
How a doctor approaches wellness | keto and fasting | egg freezing | vaginas and vulvas | good habits | health testing and health anxiety | Dr Zoe’s...
Avoiding fame, finding zen, and why I haven't seen myself in 'Love Actually' - Sienna Guillory
11 Feb 2025
Contributed by Lukas
Celebrity culture | Learning lines + brain health | The ‘Love, actually’ experience | modelling + the 90s | The Carrier company | Dealing with cr...
I've tried every treatment / tweakment going; this is what works - Alice Hart Davis
04 Feb 2025
Contributed by Lukas
Injectables | Skincare | Gadgets | LED and laser | Regulations in aesthetics | Make-up | Surgery | Body treatments | Tricky areas | Ultimate tips | Br...
My ultimate make-up recommendations and tips – Caroline Barnes
28 Jan 2025
Contributed by Lukas
Heaps of product recommendations | BB and CC creams | dealing with eye issues | spots / concealers | foundation | mascara | building a make-up artist ...
What a beauty editor loves, uses, and rates - Rosie Green
21 Jan 2025
Contributed by Lukas
Recovering from heartbreak | couples therapy | creams and lotions - treatments and tweakments | rosacea | anxiety | lessons learned
How I built a £30m brand with collagen as the hero - Maxine Laceby
14 Jan 2025
Contributed by Lukas
Baring all aged 49 | What are your brand non-negotiables? | Figuring out digital marketing | ADHD | eye health | Running | Skincare, supplements - an...
How yoga nidra transformed my nervous system - Victoria Woodhall
07 Jan 2025
Contributed by Lukas
Yoga nidra | rocket yoga | burn-out | thinning hair | Gilbert's syndrome | wellness tech | menopausal bladder weakness | a list of beautiful fragrance...
Skin tracking - is this the future of ageing well?
31 Dec 2024
Contributed by Lukas
Prof. Mark Birch-Machin is the founder of Skin Life Analytics and a professor in Molecular Dermatology with a deep expertise is in how our skin ages -...
Slow down and breathe - with Rob Rea
24 Dec 2024
Contributed by Lukas
Different breathwork techniques | are we over-breathing? | using breathwork to trigger the parasympathetic nervous system | can breathwork create a ps...
Sugar + sweeteners (the latest thinking, gurus, products, and data)
17 Dec 2024
Contributed by Lukas
Dr Sophie explains some of the newest thinking based on the latest studies – from supplements that remove sugar through to credible sugar alternativ...
Sure, give up caffeine – but not coffee. Here’s why.
10 Dec 2024
Contributed by Lukas
Dr Sophie unpacks compelling NEW evidence on coffee and discusses why we should separate coffee from caffeine – with plenty of new thinking, recomme...
Bath oils | PJs | CBD | candles | hair | make-up | skincare > Dr Sophie's favourite things
03 Dec 2024
Contributed by Lukas
Yes there's skincare but so much more. Think of this as your ultimate Christmas Gift wish list.
Meet Prof David Nutt and find out how cannabis is radically changing lives
26 Nov 2024
Contributed by Lukas
For anyone with anxiety, epilepsy, MS (and more), this episode will be a powerful listen. Did you know you can get a legal prescription in the UK? Thi...
Meet Nick Birch and find out why women need to take their bone health *way* more seriously
19 Nov 2024
Contributed by Lukas
What happens to women’s bones when she reaches peri-menopause / why osteoporosis is a silent and hormone related disease / how to reverse osteoporos...
Meet Smita Sinha and find out how she's transforming women's vaginal and vulval health
12 Nov 2024
Contributed by Lukas
Things have moved on in the women’s intimate healthcare space - from vaginal radio frequency to vulval injectables. We discuss pelvic floor strength...
Meet Dr Bita Fox and find out why her work on oral health has become so important
05 Nov 2024
Contributed by Lukas
This is about so much more than teeth - because the oral microbiome is now being connected to all kinds of disease and disorder - and Dr Bita is now a...
A review of at-home health test kits
29 Oct 2024
Contributed by Lukas
Stool testing our microbiome + saliva genetic tests + a test that measures our true biological age + DUTCH test hormone checks + how to manage the MTH...
Is tap water ok? + water filters explained + the buzz around 'wellness water'
22 Oct 2024
Contributed by Lukas
How is water cleaned? What’s the best way to filter? Is ‘hydrogen’ water a thing? What should we know about bottled water? What about drinking w...
Infrared explained
15 Oct 2024
Contributed by Lukas
What *is* infrared - and why are so many people talking about infrared saunas and sauna blankets? Can it really help with pain and stiffness? What are...
The latest data on how to radically improve your brain health (inc. 'menopause brain')
08 Oct 2024
Contributed by Lukas
The critical role of exercise, stress, sleep, smart phones - and digital dementia - PLUS oral bacteria / relaxation anxiety / menopause / supplements ...
Cold water therapy (and how it's transforming menopausal mood swings, anxiety, and hot flushes)
01 Oct 2024
Contributed by Lukas
A deep dive into so-called cold water therapy – from sea swimming and ice tubs to the Wim Hof method - plus *new data* on how it's making a big dif...
No-needle anti-ageing? Why everyone's buzzing about Sofwave (+ the lowdown on other in-clinic 'energy' devices)
24 Sep 2024
Contributed by Lukas
How to pick the right energy device treatment | The latest tech | Why Dr Sophie is so impressed by Sofwave | New treatments for cellulite | What Dr S...
Skin peels - how they've evolved and why they're still an 'A' lister's favourite, in-clinic
17 Sep 2024
Contributed by Lukas
A full explainer inc. the do’s, the don’ts, how peels have changed over the years – and why it’s such an enduringly popular staple in the skin...
Fake tan for grown-ups (how to keep that summer glow going + loads of new tips)
10 Sep 2024
Contributed by Lukas
How to tan the face… stop streaks…avoid orange…get rid of it fast (plus make it last longer). A bunch of tips and ideas that truly work - plus n...
The vaginas + vulvas episode
03 Sep 2024
Contributed by Lukas
How to wash 'down there' + vaginal discharge + recurrent UTIs / thrush + pelvic floor / bladder weakness + devices and trainers + vaginal atrophy / pa...
“From sex drive to fertility – this is a men's health pandemic." – Dr Tracy Gapin *guest ep*
27 Aug 2024
Contributed by Lukas
Why men's fertility is declining / erectile dysfunction / what men need to know about prostate cancer screening / testosterone tests + men's HRT / thy...
“We now have hard evidence that THIS will slow cellular ageing" - Dr Nichola Conlon *guest ep*
20 Aug 2024
Contributed by Lukas
We talk to one of the world's leading experts on cellular ageing including the molecule that changed it all – and the innovative, award-winning, *da...
"Yes, I take sides in couples therapy. Here's why..." - Terry Real *guest ep*
13 Aug 2024
Contributed by Lukas
Terry’s client list ranges from Gwyneth Paltrow to Bradley Cooper. This chat covers everything from sex to affairs to how to calm down from vicious ...
“Loss of nitric oxide is directly linked to almost every chronic disease” – Dr Nathan Bryan *guest ep*
06 Aug 2024
Contributed by Lukas
What disrupts it (inc. how we brush our teeth); how to increase it; why not all supplements are created equal; testing protocols; the link with sexual...
“Psychedelic drugs are creating profound change for trauma and addiction” – Tracey Tee *guest ep*
30 Jul 2024
Contributed by Lukas
How psilocybin works on serotonin, the ‘feel good’ hormone. Why people are using it for alcoholism, depression, PTSD, and anorexia. Ideas, anecdo...
"Do not bring your phone into the bedroom!" - Boniface *guest ep*
23 Jul 2024
Contributed by Lukas
How Boniface uses osteopathy to work with deep-rooted (and generational) trauma. Plus: the vagus nerve / being addicted to our own stress / working wi...
"This is how to train your brain - and improve your memory" - Prof Mark D'Esposito *guest ep*
16 Jul 2024
Contributed by Lukas
Are smart phones making us dumb? Can the brain be 'trained'? Do brain health supplements actually work? We also look at the surprising role of dopamin...
"I shot up to 1 million - then 2 million followers" - Danae Mercer on going viral *guest ep*
09 Jul 2024
Contributed by Lukas
Body image, filters, the road to self esteem, marrying a man who’s your biggest champion – and what happened to Danae after she posted *that* inc...
"This is why our poop matters" - ZOE's Dr Will Bulsiewicz *guest ep*
02 Jul 2024
Contributed by Lukas
HUGELY powerful data on one food group + why do our bathroom habits matter? + do probiotics *really* work? + the vaginal microbiome + brain fog / ment...
At-home biohacking that actually works
25 Jun 2024
Contributed by Lukas
The devices Sophie loves inc. the latest science and data + a range of budget options + more on the hyped device EVERYONE is talking about + and an un...
Microneedling for beginners
18 Jun 2024
Contributed by Lukas
Is it true Victoria Beckham loves it? What about these at home devices – are they worth it? Does microneedling hurt? What downtime do we need? In 16...
Necks, knees, hands, jowls (+ other tricky areas)
11 Jun 2024
Contributed by Lukas
Dr. Sophie runs through a range of aesthetic options for those tricky areas with a focus on the latest non-surgical solutions (and a host of other ide...
A crib sheet on fillers
04 Jun 2024
Contributed by Lukas
Literally every question you could possibly ask – inc. how to achieve the most natural look and an explainer on different products v different brand...
Teen skin
28 May 2024
Contributed by Lukas
The skincare ingredients to add – and avoid. Plus a range of tips – what the doctor can (and can’t) prescribe - and a full explainer on Roaccuta...
Taking a holistic approach to cancer - part 2
21 May 2024
Contributed by Lukas
We pick up from last week inc. the latest data on the mind-body axis, off-licence meds, autophagy, gut health, and dental health. Always consult your ...
Taking a holistic approach to cancer - part 1
14 May 2024
Contributed by Lukas
The latest data on a range of vitamins and supplements - plus the role of the immune system, and how to supplement if you’re in active treatment. **...
The pregnancy and breastfeeding episode
07 May 2024
Contributed by Lukas
The stuff to avoid / treatment-grade actives / what if you've had injectables before knowing you're pregnant? Plus stretch marks / pelvic floors / mel...
So what's the deal with lasers (+ LED / IPL)?
30 Apr 2024
Contributed by Lukas
The lowdown on ALL your options if you’re looking for a needle-free approach to aesthetics.
16 things you need to know about sunscreen
23 Apr 2024
Contributed by Lukas
The surprising places you should wear sunscreen – the reapplication question – mineral v chemical – and ‘that’ TikTok trend totally explaine...
Everything you wanted to know about wrinkle relaxers
16 Apr 2024
Contributed by Lukas
Myth-busting, protocols, and the very best advice on how to achieve the natural look.
Cellulite, stretch marks, stubborn fat and loose skin
09 Apr 2024
Contributed by Lukas
A *body positive* explainer inc. pioneering new treatments, and a surprisingly obvious choice for stretch marks. Dr Sophie covers off what really work...
A run-down on rosacea / sensitive skin
02 Apr 2024
Contributed by Lukas
...including a blast of all products and treatments and really interesting new studies emerging. PLUS is acne rosacea another 'thing' for women in per...
Hair loss | hair thinning | hair health
26 Mar 2024
Contributed by Lukas
A chat mostly about hair loss and hair thinning (along with all the treatments available) + general advice on keeping hair shiny, healthy, and happy.
How to get the best night’s sleep of your life
15 Mar 2024
Contributed by Lukas
Happy World Sleep Day! From apps and wearables to weighted blankets, high-tech mattresses, new biohacking devices + supplements, melatonin, CBD…and ...
Active skincare proven to work on lines and wrinkles
12 Mar 2024
Contributed by Lukas
Can someone get away with just using certain ingredient blends / products? What about the retinoids versus peptides debate (and emerging data on pepti...
Are you ready for skin boosters yet?
05 Mar 2024
Contributed by Lukas
Stuck in a skincare rut? Newbie to boosters? We’ve got you covered. Dr. Sophie covers what they do. How they work. Plus how they compare (and combin...
All-things EYES (wrinkles / supp's / peri-meno + vision)
27 Feb 2024
Contributed by Lukas
From aesthetics for bags and wrinkles to dealing with dark circles PLUS general eye health - including supplements and how the peri-meno and screentim...
'Regenerative aesthetics': the next-gen of skincare
13 Feb 2024
Contributed by Lukas
So, what’s new and what’s next? Dr. Sophie takes a look at the latest trends, technologies and innovations when it comes to anti-ageing treatments...
*The supplements ep* - a new approach to vitamins, adaptogens, nootropics + herbs
30 Jan 2024
Contributed by Lukas
From longevity supp’s to hormonal help (to exactly *how* to take vitamin D, and its little-known benefits). CBD. NAD. MCT. It’s all here, and more...
The surprising magic of mushrooms
16 Jan 2024
Contributed by Lukas
From skincare to supplements, Dr. Sophie brings a science-led round-up of the key ingredients that can boost skin, combat stress and improve sleep.
Aesthetics + self-esteem + feminism + new regulations (and more)
02 Jan 2024
Contributed by Lukas
Can you be a feminist and have injectables? Are we in danger of chasing the same look? What about the lack of UK regulations? Or celebs who *claim* to...
The gut + the skin + the vaginal microbiome + cellular ageing
19 Dec 2023
Contributed by Lukas
New data...new ideas...new-age probiotics PLUS vaginal health, the skin’s microbiome - and the interesting role of prebiotics.
Dr Sophie’s acne protocol
05 Dec 2023
Contributed by Lukas
Hormones, HRT, and the right kind of skincare - plus: Roaccutane (and other meds), in-clinic options, scarring, diet, alternative treatments…this is...