The API-CAT trial: A Discussion with Isabelle Mahé, Principal Investigator

A cardiologist by training, Isabelle Mahé is Professor of Internal Medicine at Université Paris Cité. She is Head of the Internal Medicine Department at a teaching hospital (Louis Mourier, Assistance Publique Hôpitaux de Paris, Paris, France), which includes an oncology unit and a vascular disease unit. She established a tele-expertise service to help physicians manage patients with anticoagulant concerns. She is also chair of the scientific council for the INNOVTE-FCRIN Network (Investigation Network On Venous Thrombo-Embolism) and for a patients' association for anticoagulant therapy (Anticoag PASS S2D). She has broad experience in methodology and in clinical trials evaluating anticoagulants in different cardiologic or vascular indications. Her own research projects have resulted in a better management of anticoagulants in complex patients (renally impaired, elderly and cancer patients. She is leading the international prospective randomised API-CAT Study (focusing on the extended anticoagulant treatment in patients with cancer-associated thrombosis).Sebastian Szmit graduated from the Military Medical Academy in Poland (2002). From 2002 to 2012 he worked at the Military Institute of Medicine in the (1) Emergency Department, (2) Department of Internal Medicine and Cardiology, (3) Department of Oncology. From 2012 to 2022 he was employed by the Department of Pulmonary Circulation, Thromboembolic Diseases and Cardiology as cardiologist consultant of the Department of Oncology at the European Health Centre Otwock. In December 2022 he was appointed the Head of the Department of Cardio-Oncology, Centre of Postgraduate Medical Education at the Institute of Hematology and Transfusion Medicine & Consultant of the Cancer Diagnostics and Cardio-Oncology at the Maria Skłodowska-Curie National Research Institute of Oncology (Warsaw, Poland). He is cardiologist & clinical oncologist.Read the full trial results here: https://www.nejm.org/doi/full/10.1056/NEJMoa2416112

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