Feedback00:52 Intro: definition and prompts04:25 Intro to Case 1: Haemophilia B, 3rd dose of BeneFix Anaphylaxis 06:03 Intro to Case 2: Severe Haemophilia A, joint bleed, non-responsive to emergency Factor VIII07:30 Initial screening tests NB: Inhibitors: Time Dependent vs. Immediate Acting14:54 Flash examples of Mixing Study importance16:35 Bethesda Assay **Bethesda Studios made the Elder Scrolls and Fallout games: they Inhibit Haider from doing any work**28:45 Bethesda Assay Summary30:00 Nijmegen Modification of Bethesda Assay34:30 Heat Treatment of Bethesda Assay 36:25 ELISA Assay 40:30 Auto vs Allo Antibodies42:00 Kinetics of a Time Dependent Inhibtor 44:45 Case 1 results45:50 Case 2 results51:00 Case 3 (real-life scenario): young girl, subdural bleed after fall, deranged clotting found incidentally 59:30 Summary 'Basics to Brilliance: Haematology Podcast' has been accredited for CPD credit by the Royal College of Pathologists UK. Medical professionals and clinical scientists holding career-grade positions, who are registered with any of the Royal Colleges for CPD, will be eligible to earn 1 credit for every hour of learning. Email: [email protected] Insta: BasicstoBrilliance X: @basics_2_brill Send us your feedback!

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