Katya Krykunova from the University of Ottawa interviews Dr. Marisa Azad from The Ottawa Hospital about the first use of phage therapy in Canada. Dr. Azad's patient developed a life-threatening periprosthetic joint infection (PJI) of her hip implant. She was allergic to most major antibiotics; the culprit bacteria were resistant to all others, and further surgery would risk her life. All conventional treatments were exhausted. With the patient’s condition declining, Dr. Azad decided to team up with Cytophage Technologies and pursue phage therapy as a last resort. In this episode, Dr. Azad walks us through this clinical case and highlights how phage therapy offers an alternative approach for targeting infections when antibiotics and surgery fail. Learn more: https://www.mdpi.com/1999-4915/17/8/11180:04 | BEaTS and host introduction0:20 | What is phage therapy?0:56 | Introduction to Dr. Marisa Azad2:52 | What are PJIs?4:26 | Using phage therapy for a severe case of PJI7:29 | Making phage therapy possible for this patient in collaboration with Cytophage Technologies9:26 | Ensuring the safety and efficacy of phage therapy11:22 | Insights from Dr. Brad Cook from Cytophage Technologies11:55 | What Dr. Azad has learned throughout the process13:27 | Science, medicine, and art14:32 | Concluding remarksSoundtrack by The Underground Drive. All rights reserved. Listen more:https://music.apple.com/ca/artist/the-underground-drive/1571062779https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmRShow Host: Katya KrykunovaProducer: Meghan WalshWriter: Sydney Brown, Katya KrykunovaContent generation: Talia LoFaro, Meghan Walsh, Katya KrykunovaEditor: Meghan Walsh, Katya Krykunova, Sydney Brown, Talia LoFaroAudio post-production: Sydney BrownSocial media coordinator: Talia LoFaro

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