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Brain Talk | Being Patient for Alzheimer's Patients and Caregivers

Early-Onset Alzheimer’s: Anthony and Karen Sandone’s Journey

09 Dec 2025

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Before his symptoms began, Anthony and Karen Sanone were always on the move, traveling, working and staying active. A former college athlete who played football and baseball, Anthony spent more than 35 years as a chemical sales manager. Karen, a director of human resources at an education agency, now balances her professional role with caregiving. The couple documents their experiences on Anthony’s Instagram account, @anthony_vs_alzheimers, and through their younger-onset caregiver community, Surviving the Now.In this conversation with Being Patient’s Mark Niu, Anthony and Karen talk about the early warning signs and the long, often confusing road to a younger-onset Alzheimer’s diagnosis. They discuss navigating work, pursuing treatment with Leqembi, managing seizures, and reshaping daily life around routines, travel strategies, and safety. Karen also shares candid advice on planning for the future, building a support system and finding ways to “live in the moment” and make meaningful memories, even as the disease progresses.-- If you loved listening to this Live Talk, visit our website to find more of our Alzheimer’s coverage and subscribe to our newsletter: https://www.beingpatient.com/Follow Being Patient: Twitter: https://twitter.com/Being_Patient_Instagram: https://www.instagram.com/beingpatientvoices/Facebook: https://www.facebook.com/beingpatientalzheimersLinkedIn: https://www.linkedin.com/company/being-patientBeing Patient is an editorially independent journalism outlet for news and reporting about brain health, cognitive science, and neurodegenerative diseases. In our Live Talk series on Facebook, former Wall Street Journal Editor and founder of Being Patient, Deborah Kan, interviews brain health experts and people living with dementia. Check out our latest Live Talks: https://www.beingpatient.com/category/video/

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