Cell Culture Dish Podcast
Episodes
Advancing Closed-System Performance: How CPC’s MicroCNX® Connectors Enable Scalable Cell and Gene Therapy Manufacturing
09 Dec 2025
Contributed by Lukas
In this podcast, we spoke with Troy Ostreng, Senior Product Manager and David Burdge, Director of Cell and Gene Therapy at CPC about the development o...
Inside ATLAS – Transforming Surfactant Monitoring in Bioprocessing
20 Aug 2025
Contributed by Lukas
Surfactants are indispensable in the production of biologics, vaccines, and cell therapies. Yet for years, they’ve posed a persistent challenge: the...
From Storage Tanks to Smart Systems: The Evolution of Buffer Preparation
30 Apr 2025
Contributed by Lukas
In this podcast, we spoke with Nainesh Shah, Sr. Application Engineer, Asahi Kasei Bioprocess America, about how inline buffer formulation and their M...
Unlocking the Potential of Induced Pluripotent Stem Cells: Innovations, Challenges, and Future Directions
22 Jan 2025
Contributed by Lukas
In this podcast, we spoke with Dr. Jorge Escobar Ivirico, Product Manager, Bioprocess Solutions at Eppendorf, about the fascinating world of induced p...
Accelerating Bioprocess through Digital Transformation: A Strategic Path Forward
12 Dec 2024
Contributed by Lukas
In an era where industries are increasingly driven by data and automation, the bioprocessing sector is embracing digital transformation to streamline ...
The Key to Biologics Success: Why Developability Assessments Matter in Antibody Discovery
21 Nov 2024
Contributed by Lukas
In this podcast, we spoke with Dr. George Wang, Vice President of Discovery and Preclinical Services at WuXi Biologics about the importance of identif...
New Cell Culture Select Tool Simplifies Cell Culture Selection for Researchers
13 Nov 2024
Contributed by Lukas
In this podcast, we spoke with Isha Dey, Senior Scientist, Cell Biology R&D, at Thermo Fisher Scientific about the challenges researchers face in sele...
Revolutionizing Cellular Therapies: How Automation is Transforming the Industry
12 Nov 2024
Contributed by Lukas
In this podcast, we spoke with Ryan Bernhardt, CEO of Biosero and Jesse Mulcahy, Director and Head of Automation at Cellino about the importance of ut...
Pioneering Access and Innovation: The Future of Cell and Gene Therapies
23 Oct 2024
Contributed by Lukas
In this podcast, we spoke with Fran Gregory, Vice President of Emerging Therapies at Cardinal Health about the cell and gene therapy landscape, innova...
How AGC Biologics received approval from both US and European regulators for commercial manufacture of Lenmeldy – A cell-based gene therapy
05 Jun 2024
Contributed by Lukas
In this podcast, we spoke with Luca Alberici, Senior Vice President and General Manager, Milan Facility, AGC Biologics about the road to their recent ...
How Real Time Titer Measurement And Monitoring Is Advancing Bioproduction Across Multiple Applications
29 Feb 2024
Contributed by Lukas
This panel discussion was originally published in the eBook “ Monoclonal Antibody Manufacturing Trends, Challenges, and Analytical Solutio...
Advancements in Buffer Management and Single Use Inline Buffer Formulation
15 Feb 2024
Contributed by Lukas
In this podcast, we spoke with Nainesh Shah, Senior Application Engineer at Asahi Kasei Bioprocess about buffer management including the benefits of i...
Executing Efficient Scale-up and Large-Scale Viral Vector Manufacturing
07 Dec 2023
Contributed by Lukas
In this podcast, we spoke with Margherita Neri, Director of Vector Process Development, Milan Site at AGC Biologics, Andrew Laskowski, Global Product ...
Advancements in Cell and Gene Therapy Stirred-Tank Bioreactor Suspension Culture
17 Apr 2023
Contributed by Lukas
In this podcast, we talked with Dr. Ma Sha, Head of Bioprocess Applications at Eppendorf SE about advancements and challenges in cell and gene therapy...
Sangamo’s gene therapy product candidate for Fabry disease shows continued tolerability and promise as an alternative to Enzyme Replacement Therapy
02 Feb 2023
Contributed by Lukas
In this podcast, we talked with Nathalie Dubois-Stringfellow, Senior Vice President of Product Development and Management at Sangamo about Sangamo’s...
Single-use Mixers – Ensuring the Customization, Scalability and Supply Required for Success
15 Dec 2022
Contributed by Lukas
In this podcast, we talked with Dennis Hodgson and Phil Sanders from Agilitech about the benefits of single-use mixers, dealing with supply chain conc...
New online Gene Therapy Academy offers great resources to support scaling up from lab to production scale
14 Dec 2022
Contributed by Lukas
In this podcast, we spoke with Emanuel Krobath, Biopurification Specialist and Chiara Pacini, Bioprocess Specialist both with Pall Corporation about ...
Increasing Liquid Chromatography Efficiency with Fully-controlled Binary Blending
12 Dec 2022
Contributed by Lukas
In this podcast, we spoke with Cory Hinz, Engineering Manager at Asahi Kasei Bioprocess about the different methods that are available for liquid ...
Biomanufacturing Quality Management Systems – A holistic approach
05 Dec 2022
Contributed by Lukas
In this podcast, we interviewed Katie Keller, Director of Quality and Safety at Asahi Kasei Bioprocess America, about the importance of quality manage...
Flexible single-use mixers are key to achieving a next level mixing experience and reducing delivery lead times
21 Nov 2022
Contributed by Lukas
In this podcast we spoke with Klaus Kienle, Global Product Manager for the Mixing portfolio at Pall Corporation about the latest mixing technologies i...
Manufacturing high concentration mAbs challenges and solutions
14 Nov 2022
Contributed by Lukas
In this podcast, we spoke to Tom Watson, Group Leader, Product Management – Biotech Division, Gregor Kalinowski, Manager SLS Purification Consultant...
A Guide for Navigating the Single Use Technology Supply Chain
07 Nov 2022
Contributed by Lukas
In this podcast we spoke with Derrick Alig, North American Western Regional Sales Manager for PSG Dover Biotech, Chris Couper, President and Founder o...
Upstream and Downstream Processes – A Holistic View
12 Oct 2022
Contributed by Lukas
This article was originally published in the eBook “ Future proofing Bioprocessing from Upstream to Downstream”. You can download all the articl...
Optimizing Process Development Early – A critical factor in successful viral vector scale up and large scale manufacture
11 Jul 2022
Contributed by Lukas
In this podcast, I spoke with John Ketz and Denis Kole about viral vector production, including current manufacturing challenges, navigating the road ...
Using End-to-End Integrated Solutions to meet the High Demand for Viral Vector GMP Manufacturing
14 Jun 2022
Contributed by Lukas
In this podcast, I spoke with Hanna Lesch Ph.D., Chief Technology Officer at Exothera about viral vector manufacturing. We discussed current industry ...
Streamline the ADC Path to the Clinic with One-stop Drug Development and Critical Technology Advancements
20 Dec 2021
Contributed by Lukas
In this podcast, I talked with Dr. Jimmy Li, CEO of WuXi XDC, a WuXi Biologics subsidiary. We discussed the reasons for the formation of WuXi XDC, whi...
The benefits of using a single-source for discovery, development and GMP manufacture of antibody drug conjugates and other novel bioconjugates
15 Dec 2021
Contributed by Lukas
In this podcast, I talked with Dr. Jimmy Li, CEO of WuXi XDC, a WuXi Biologics subsidiary. We discussed the reasons for the formation of WuXi XDC, whi...
Increasing speed and efficiency of biotherapeutic drug development with stable pools
01 Dec 2021
Contributed by Lukas
In this podcast, we talked with Dr. Alison Porter, Head of Expression System Sciences, Lonza, about the use of stable pool expression to reduce drug d...
Addressing the increasing demand for single-use technologies and supply chain shortages with future proof systems
19 Nov 2021
Contributed by Lukas
Phil Sanders talks about the increase in demand for single-use equipment and consumables and how this has led to supply chain shortages.
Implementing Adherent Cell Culture Technology for Cell Therapy Bioprocess
23 Sep 2021
Contributed by Lukas
Several of the most promising candidates in the pipeline use mesenchymal stromal cells and pluripotent stem cells, both of which require an adherent s...
Evolving Beyond the Status Quo with Next Generation Buffer Prep Solutions
08 Sep 2021
Contributed by Lukas
In this podcast, we spoke with Chris Rombach, Vice President of Sales and Marketing at Asahi Kasei Bioprocess America about buffer prep and delivery s...
Integrated Freezing Solutions to Minimize Risk and Preserve Product Quality
27 Apr 2021
Contributed by Lukas
Claire Jarmey-Swan, Global Product Manager, Pall Corporation talks about the evolution freeze thaw technologies and how these new methods can streamli...
Enabling process development for continuous bioprocessing: Answering the call for small scale tools that are fit for purpose
06 Apr 2021
Contributed by Lukas
The priority of speed to market is often at odds with issues around development resources, facility space, and infrastructure for both development and...
The CHO Cell Line – From Reliable Workhorse to State-of-the-art Protein Powerhouse
09 Mar 2021
Contributed by Lukas
Alan Dickson talks about the evolution of the CHO Cell line from isolation to workhorse of the biomanufacturing industry, to gene edited knockout vari...
The Secret Ingredient in Your Gene Therapy Success Recipe
11 Feb 2021
Contributed by Lukas
In this podcast, Ratish Krishnan, Associate Director for Cell & Gene Therapy BioProcessing for the Americas at MilliporeSigma about the importance...
3D cell culture bioreactor system for growing and maintaining spheroids and organoids with the structure and function of in vivo cells
03 Feb 2021
Contributed by Lukas
In this podcast, we spoke with Dr. Stephen Fey, Chief Research Officer and Co-founder, CelVivo about the importance of 3D culture and the challenges...
Optimizing Protein Expression and Purification using Mass Spectrometry Analysis
17 Dec 2020
Contributed by Lukas
In this podcast, we conducted a panel discussion with experts from Peak Proteins on common protein challenges and the use of mass spec to overcome exp...
New Lab Set Up – Best Practices for a Successful Start
18 Nov 2020
Contributed by Lukas
In this podcast, we spoke with Dr. Ann Rossi Bilodeau, Senior Bioprocess Applications Scientist and Dr. Catherine Siler, Field Applications Scientist ...
Demystifying the FBS Selection Process – A guide for evaluating product quality, origination and cost consideration
13 Oct 2020
Contributed by Lukas
In this podcast, we talked with Chris Scanlon, Global Marketing Development Manager at Thermo Fisher Scientific about how to effectively evaluate whic...
Reducing Fill Risk in Drug Product Manufacture Utilizing New State-of-the-Art Systems and Platforms
16 Sep 2020
Contributed by Lukas
In this podcast we talked with DQ Wang, PhD, and Vice President, Formulation, Fill and Finish of WuXi Biologics about their DP4 multi-product fill & f...
The Challenge of Staying Current with Regulatory Changes – How one company is providing a solution
10 Sep 2020
Contributed by Lukas
In this podcast, we talked with Ken Chen, MBA, Senior Director, Regulatory Affairs, WuXi Biologics about staying current with regulatory changes. We d...
Computer Aided Biology Platform Helps Companies Meet the Challenges of 21st Century Biomanufacturing
08 Sep 2020
Contributed by Lukas
In this podcast, we interviewed Markus Gershater, Chief Scientific Officer with Synthace about computer-aided biology and how it addresses several co...
Balancing Risk, Cost and Speed During Clinical Development While Still Maintaining Quality
27 Jul 2020
Contributed by Lukas
In this podcast, we talked with Thierry Cournez Vice President, BioReliance® End-to-End Solutions, MilliporeSigma. We discussed effective ways for em...
Solving the challenges of standardizing cell counting to ensure reproducibility in experiments, assays and manufacturing processes
07 Jul 2020
Contributed by Lukas
In this podcast we talked with Christian Berg, Global Product Manager at Chemometec about the importance of standardizing cell counting because while ...
A Look Towards the Future of 3D Cell Culture – A panel discussion
01 Jul 2020
Contributed by Lukas
This article is the fourth in a series that was published in the eBook “3D Model Systems: Spheroids, Organoids and Tissue Models”. You can downl...
Multistem – A Stable, Off-the Shelf Regenerative Medicine Has Demonstrated Promise in Treating Patients with Acute Respiratory Distress Syndrome or ARDS
04 Jun 2020
Contributed by Lukas
In this podcast, we talked with Dr. Gil Van Bokkelen, Chairman and CEO, Athersys about recent clinical breakthroughs in regenerative medicine and manu...
Bi-Specific Antibodies – The development, manufacture and promise of these cutting-edge therapeutics
27 May 2020
Contributed by Lukas
In this podcast, we conducted a panel discussion with experts from Selexis and KBI Biopharma on bi-specific antibodies. We examined bi-specific antibo...
Rapid At-line Media Analyzer Speeds Process Development by Eliminating Analytics Bottleneck
14 May 2020
Contributed by Lukas
In this podcast, we talked with Dr. Glenn Harris, Director of Integrated Life Sciences Platforms at 908 Devices, about the benefits and challenges ...
Non-Animal Origin cell culture supplements and manufacturing aids for biologics manufacturing
11 May 2020
Contributed by Lukas
In this podcast, we talked with Dr. Tobias Hertzig, Regulatory Affairs Manager and Dr. Ulrich Tillmann, Global Product Manager, Supplements and Manufa...
Mesenchymal Stem Cell Culture – Challenges and solutions for isolation, expansion and maintenance
25 Mar 2020
Contributed by Lukas
In this podcast and accompanying article, we talked with Dr. Jennifer Chain, Scientific Director of Research and Development, Oklahoma Blood Institute...
CryoVault Freeze and Thaw Platform Provides a Scalable, Robust and Single-Use End-to-End Solution for Bulk Drug Substance
11 Feb 2020
Contributed by Lukas
In this podcast, I talked with Max Blomberg, Executive Director of Operations and Andrew Govea, Senior Product Engineer, at Meissner about the chall...
Generating actionable data and analysis in complex models using live-cell analysis
12 Dec 2019
Contributed by Lukas
In this podcast and accompanying article, we talked with Paul Jantzen, Product Manager for IncuCyte at Sartorius about the benefits of real-time live-...
Improved gene therapy analytics permit monitoring of critical quality attributes and increased manufacturing efficiency
11 Dec 2019
Contributed by Lukas
In this podcast and accompanying article, we interviewed Jonathan Royce, Director, Instruments Business Unit, Vironova about analytics in gene therapy...
New Advancements in Cell and Gene Therapy Implementing Precision Medicine
10 Dec 2019
Contributed by Lukas
In this podcast and accompanying article, we talked with Dr. Paul Wotton, Chief Executive Officer, Obsidian Therapeutics about the evolution of cancer...
Live Cell Analysis for Neuroscience Research
29 Oct 2019
Contributed by Lukas
In this podcast, we talk with Susana Alcantara, Senior R&D Scientist and Neuroscience Program Leader, BioAnalytics, Sartorius about the ways real-time...
Using 3D cell-based human liver microtissue models in predicting adverse effects caused by chronic exposure to engineered nanomaterial
13 Oct 2019
Contributed by Lukas
In this podcast and accompanying article, we interviewed Dr. Shareen Doak, Professor of Genotoxicology and Cancer at Swansea University Medical Schoo...
Raw Material Quality – Identifying and Mitigating Variation
24 Sep 2019
Contributed by Lukas
In this podcast, we interviewed Cory Card, Principal Scientist Life Sciences, GE Healthcare about raw material quality, its impact on cell culture...
Antibody Drug Conjugate (ADC) Development and Manufacturing Challenges and Solutions
09 Sep 2019
Contributed by Lukas
In this podcast, we interviewed Dr. J.J. Luo, Executive Director and Dr. Lily Yin, Head of Biologics Conjugation Development, at WuXi Biologics ...
Mustang Bio’s gene therapy has tremendous potential to cure XSCID or Bubble Boy Disease based on study results from St. Jude
31 Jul 2019
Contributed by Lukas
In this podcast, we interviewed Dr. Manny Litchman, President and CEO, Mustang Bio and Dr. Knut Niss, Chief Technology Officer, Mustang Bio about the ...
Successful Methods for Perfusion Process Optimization
24 Jul 2019
Contributed by Lukas
In this podcast, we interviewed Dr. Andreas Castan, Principal Scientist at GE Healthcare Life Sciences about the best methods for optimizing perfusi...
How Live Cell Analysis Technology is Meeting the Needs of Ever Evolving Advanced Cell Models
26 Jun 2019
Contributed by Lukas
In this podcast and accompanying article, we interviewed Dr. Kimberly Wicklund, Head of Product Management for the IncuCyte® at Sartorius about ho...
Innovative vaccine manufacturing enables the delivery of vaccines to the developing world
19 Jun 2019
Contributed by Lukas
In this podcast and accompanying article, we interviewed Dr. Alex Chatel, Product Manager, Viral Applications, Univercells about the biggest challenge...
Optimizing Fed Batch Culture – Developing New Tools and Methods to Improve Production
29 May 2019
Contributed by Lukas
In this podcast and accompanying article, we interviewed Dr. Aline Zimmer, Head of R&D, Advanced Cell Culture Technologies at Merck about the importan...
Using cell culture models of endocrine resistance to improve triple positive breast cancer treatment options.
01 Apr 2019
Contributed by Lukas
Gibco Cell Culture Hero, Dr. Hillary Stires discusses her work researching better treatment options for triple positive breast cancer patients. She ex...
Integrating bioprocessing steps to improve efficiency and reduce cost
21 Feb 2019
Contributed by Lukas
In this podcast, we interviewed Dr. Rick Morris, Senior Vice President, R&D, Biotech, Pall Life Sciences, about integrating bioprocessing steps to...
Expediting cell and gene therapy workflows
06 Feb 2019
Contributed by Lukas
In this podcast and accompanying article, we interviewed Mr. Dave Eansor President of the Protein Sciences Segment at Bio-Techne and Dr. Sean Kevla...
A Road Map for Efficient Fed-Batch Cell Culture Optimization
05 Feb 2019
Contributed by Lukas
In this podcast and accompanying article, we interviewed Dr. Andreas Castan, Principal Scientist at GE Healthcare Life Sciences about the most effic...
Viral Vector Manufacturing for Gene Therapy
23 Jan 2019
Contributed by Lukas
In this podcast and accompanying article, we interviewed Dr. Mats Lundgren, PhD Customer Applications Director, Life Sciences, GE Healthcare, Sweden ...
Key Considerations in Gene Therapy Manufacturing for Commercialization – A panel discussion
10 Dec 2018
Contributed by Lukas
Panel discussion that I moderated at this year’s Cell and Gene Therapy Bioprocessing and Commercialization Conference. The discussion covers the lat...
Closed System Cell Therapy Manufacturing – Moving from the lab to clinical and commercial production
26 Jul 2018
Contributed by Lukas
Panel discussion on key considerations for moving cell therapies from lab to commercial manufacturing, including the benefits of manufacturing in a cl...
Successful Mesenchymal Stem Cell Manufacturing for Cell Therapy Applications
31 May 2018
Contributed by Lukas
Dr. Ross Macdonald, CEO Cynata Therapeutics, talks about the use of mesenchymal stem cells for Cell Therapy applications and key criteria for successf...
Bioprocessing Technologies for Stem Cell Therapy
09 Apr 2018
Contributed by Lukas
Ricardo Baptista, Lead Process Development Scientist, Cell and Gene Therapy Catapult, UK talks about his impressions on current bioprocessing technol...
Cell Therapy Manufacturing – Opportunities and Challenges
20 Mar 2018
Contributed by Lukas
Dr. Robert Preti talks about the past, present, and future of global Cell Therapy manufacturing. We also discussed major industry milestones, manufact...
Novel Technology Enables Encapsulated Cell Therapies Without Triggering Fibrosis
14 Dec 2017
Contributed by Lukas
Dr. Paul Wotton, CEO, talks about Sigilon Therapeutics’ discovery platform. The platform combines cell engineering and biocompatible Afibromer™ t...
FBS – It’s Not All Created Equal – What Consumers Need to Know
09 Nov 2017
Contributed by Lukas
Alyssa Master, Ph.D., Senior Manager of Science and Applications, Nucleus Biologics talks about some of the challenges of working with FBS, why not al...
Do You Have to Sacrifice Antibody Titer for Quality? Employing cell biology to get the best of both worlds
26 Oct 2017
Contributed by Lukas
Dr. Adam Elhofy, Ph.D., Chief Scientific Officer, Bio-Ess Laboratories, talks about the relationship between antibody titer and product quality attrib...
Implementation of Single-use Bioreactors for Microbial Fermentation is Easier Than You Think
18 Oct 2017
Contributed by Lukas
Ken Clapp, a senior member of GE Healthcare Life Sciences' upstream product management team explores in more detail the implementation of single-use s...
Single-use Bioreactors for Fermentation – It’s now a reality that deserves consideration
12 Oct 2017
Contributed by Lukas
Ken Clapp, a senior member of GE Healthcare Life Sciences' upstream product management team discusses the use of single-use bioreactors for fermentati...
Bioengineered Organ Implants Poised to Change Treatment Paradigms in Esophageal Cancer
22 Jun 2017
Contributed by Lukas
Jim McGorry, CEO and Saverio LaFrancesca, President and Chief Medical Officer talk about how Biostage is using Cell Therapy to improve the standard of...
Improving lab productivity and reproducibility by taking a fresh look at existing workflows and protocols
23 May 2017
Contributed by Lukas
Sarah Simons, Automation Field Project Manager, Beckman Coulter Life Science talks about how to improve lab productivity and reproducibility by "sprin...
Smart Cell Culture Monitoring – Transforming the way we look at cells in culture
13 Apr 2017
Contributed by Lukas
Philip Mathuis, Co-founder and CEO, Ovizio, talks about cell culture monitoring, the latest technology for monitoring cells in culture without the nee...
Enabling Vaccine Manufacturing and Viral Vector Production using the iCELLis – a single-use, automated, and closed manufacturing platform
07 Mar 2017
Contributed by Lukas
In this podcast, we were fortunate to have a group of experts for a panel discussion on vaccine manufacturing and viral vector production.
Cell Culture Media Optimization – It’s about more than just high protein titer
19 Jul 2016
Contributed by Lukas
In this podcast, we interviewed Dr. Adam Elhofy, Ph.D., CSO, Essential Pharmaceuticals, about cell culture media optimization. We discussed the evolut...
Automated Stem Cell Based High Throughput Drug Screening for ALS and Parkinson’s – Dr. Jan Bruder
07 Jun 2016
Contributed by Lukas
In this podcast, we interviewed Dr. Jan Bruder about his work at the Max Planck Institute for Molecular Biology in Münster Germany and his group’s ...