Why does ibuprofen take so long to work?

#196 New College-Style Sweatshirt! Melissa and Jam delve into the science behind ibuprofen, exploring why it takes around 30 minutes to work. The discussion covers the chemistry of ibuprofen, including the concept of chiral molecules and enantiomers—molecules with mirror-image forms—highlighting how only one form of ibuprofen works effectively. The episode explains why both forms are included in the medication due to production challenges and discusses recent findings about ibuprofen's potential in cancer treatment. Additionally, the show features various fun facts about ibuprofen, aspirin comparisons, environmentally friendly production methods, and more. 00:00 Introduction and Episode Overview 05:07 Chemistry Lesson: Handedness of Molecules 17:52 Ibuprofen's Chiral Nature and Its Effects 19:15 The Racemic Mixture of Ibuprofen 24:06 The Wastefulness of Chemistry 24:29 Challenges of Purifying Enantiomers 25:16 Economic and Environmental Considerations 26:28 Understanding Ibuprofen's Handedness 27:26 The Debate on Enantiomer Separation 34:45 Fun Facts About Ibuprofen 39:55 Green Chemistry and Ibuprofen 45:42 Community and Closing Remarks References from this episode: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276492/ https://thispodcastwillkillyou.com/wp-content/uploads/2021/07/TPWKY-Episode-29-Aspirin.pdf https://www.chemistryworld.com/podcasts/ibuprofen/4011375.article https://pubs.acs.org/doi/epdf/10.1021/bi010045s?ref=article_openPDF https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355401/ 6. Garret & Grisham Biochemistry Textbook We want to give a special thanks to Bri McAllister for illustrating molecules for some episodes! Please go check out Bri’s art, follow and support her at entr0pic.artstation.com and @McAllisterBri on twitter!   Thanks to our monthly supporters Scott B Jessie Reder Ciara Linville J0HNTR0Y Jeannette Napoleon Cullyn R Erica Bee Elizabeth P Sarah Moar Rachel Reina Letila Katrina Barnum-Huckins Suzanne Phillips Venus Rebholz Lyn Stubblefield Jacob Taber Brian Kimball Emerson Woodhall Kristina Gotfredsen Timothy Parker Steven Boyles Chris Skupien Chelsea B Bri McAllister Avishai Barnoy Hunter Reardon ★ Support this podcast on Patreon ★ ★ Buy Podcast Merch and Apparel ★ Check out our website at chemforyourlife.com Watch our episodes on YouTube Find us on Instagram, Twitter, and Facebook @ChemForYourLife Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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