Nuances of NCA (Ep. 5)

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Clinical Pharmacology Podcast with Nathan Teuscher not yet transcribed

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Recorded10 Jul 2023

Publisheranchor.fm ↗

Handlerec:9442495

Show notes

In this episode, I discuss some nuances of non-compartmental analysis or NCA. I am going to focus on three separate parameters: Cmax, AUC, and the terminal elimination rate constant. These three are the most commonly used parameters to describe drug exposure. I’ll discuss the basic methodology for each and then discuss challenges that may arise when you are performing an analysis. Links discussed in the show: Images mentioned in the podcast Derivation of logarithmic AUC Calculating the elimination rate constant You can connect with me on LinkedIn and send me a message Send me a message Sign up for my newsletter Copyright Teuscher Solutions LLC All Rights Reserved

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