CorConsult Rx: Evidence-Based Medicine and Pharmacy
Episodes
Gout: Pathophysiology, Treatment Approaches, and Long-Term Management *ACPE-Accredited*
17 Feb 2026
Contributed by Lukas
On this episode, we define gout and describe its clinical presentations, etiologies, and underlying pathophysiology. We discuss current guidelines and...
Osteoarthritis: Pathophysiology, Assessment, and Management Strategies *ACPE-Accredited*
10 Feb 2026
Contributed by Lukas
On this episode, we discuss osteoarthritis and describe its clinical presentations, etiologies, and underlying pathophysiology. We review current gu...
A Review of Weight Loss Medications: Therapeutic Options and Clinical Considerations *ACPE-Accredited*
04 Feb 2026
Contributed by Lukas
On this episode, we define obesity and overweight status and describe their clinical impact, etiologies, and underlying pathophysiology. We also compa...
Thyroid Disorders: Management of Hypothyroidism and Hyperthyroidism *ACPE-Accredited*
26 Jan 2026
Contributed by Lukas
On this episode, we define hypothyroidism and hyperthyroidism and describe their clinical presentations, etiologies, and underlying pathophysiology. W...
Community-Acquired Pneumonia: Treatment and Best Practices in 2026 *ACPE-Accredited*
12 Jan 2026
Contributed by Lukas
On this episode, we discuss community-acquired pneumonia (CAP) and its clinical presentation, common etiologies, and underlying pathophysiology. We re...
Smoking Cessation: Evidence-Based Approaches and Management Strategies *ACPE-Accredited*
30 Dec 2025
Contributed by Lukas
On this episode, we discuss tobacco use disorder and describe its clinical impact, common presentations, and underlying neurobiological mechanisms. We...
Major Depression: Diagnosis and Management Strategies *ACPE-Accredited*
05 Dec 2025
Contributed by Lukas
On this episode, we define major depressive disorder (MDD) and describe its clinical presentations, diagnostic criteria, etiologies, and pathophysiolo...
Osteoporosis: A Review of Prevention and Management Strategies *ACPE-Accredited*
15 Nov 2025
Contributed by Lukas
On this episode, we define osteoporosis and describe its clinical presentations, underlying pathophysiology, and common etiologies. We compare and con...
Ulcerative Colitis: Clinical Management and Pharmacologic Updates *ACPE-Accredited*
05 Nov 2025
Contributed by Lukas
On this episode, we discuss ulcerative colitis (UC) and describe its clinical presentations, underlying pathophysiology, and common etiologies. We eva...
Open-Angle Glaucoma: A Review of Treatment Strategies *ACPE-Accredited*
28 Oct 2025
Contributed by Lukas
On this episode, we define open-angle glaucoma and describe its clinical presentations, risk factors, and underlying pathophysiolog. We evaluate curre...
Irritable Bowel Syndrome: Management Strategies *ACPE-Accredited*
03 Oct 2025
Contributed by Lukas
On this episode, we review irritable bowel syndrome (IBS) and describe its clinical presentations, subtypes, and pathophysiology. We discuss current g...
Anemia: Evaluation and Therapeutic Approaches *ACPE-Accredited*
09 Sep 2025
Contributed by Lukas
On this episode, we define anemia and describe its clinical presentations, classifications, and underlying etiologies. We evaluate current guidelines ...
Obsessive-Compulsive Disorder: Diagnosis and Treatment Strategies *ACPE-Accredited*
27 Aug 2025
Contributed by Lukas
On this episode, we define obsessive-compulsive disorder (OCD) and describe its clinical presentations, diagnostic criteria, and underlying pathophysi...
Acute Mania: An Algorithmic Treatment Approach *ACPE-Accredited*
25 Aug 2025
Contributed by Lukas
On this episode, we define acute mania and describe its clinical presentations, underlying causes, and pathophysiology. We evaluate current guidelines...
Insulin Therapy: Pharmacologic Strategies and Patient-Centered Approaches *ACPE-Accredited*
05 Aug 2025
Contributed by Lukas
On this episode, we provide an overview of insulin. We discuss the various insulin products available, basal vs prandial insulin, and dosing strategie...
Managing Insomnia: Pharmacologic and Non-Pharmacologic Approach *ACPE-Accredited*
15 Jul 2025
Contributed by Lukas
On this episode, we evaluate current guidelines and evidence-based treatment strategies for managing insomnia, including both pharmacological and non-...
Chronic Pain: Modern Approaches to Management *ACPE-Accredited*
24 Jun 2025
Contributed by Lukas
On this episode, we evaluate current guidelines and evidence-based strategies for managing chronic pain, including both pharmacologic and non-pharmaco...
Generalized Anxiety Disorder: Evidence-Based Approaches for Optimal Outcomes *ACPE-Accredited*
04 Jun 2025
Contributed by Lukas
On this episode, we evaluate current guidelines and evidence-based treatment strategies for managing GAD. We define generalized anxiety disorder (GAD)...
Chronic Coronary Syndrome: Pharmacologic Interventions *ACPE-Accredited*
16 May 2025
Contributed by Lukas
On this episode, we discuss chronic coronary syndrome (CCS) and describe its clinical presentation, underlying pathophysiology, and progression. We re...
Multiple Sclerosis: Therapeutic Strategies and Best Practices *ACPE-Accredited*
25 Apr 2025
Contributed by Lukas
On this episode, we discuss multiple sclerosis and describe its clinical presentations, types, and pathophysiology. We compare and contrast the effica...
Dyslipidemia Treatment Strategies and 2025 Guideline Update *ACPE-Accredited*
11 Apr 2025
Contributed by Lukas
On this episode we review the 2025 Clinical Practice Guideline for the Pharmacologic Management of Adults with Dyslipidemia published by the American ...
Managing Menstruation-Related Disorder *ACPE-Accredited*
30 Mar 2025
Contributed by Lukas
On this episode, we evaluate current guidelines and evidence-based treatment strategies for managing menstruation-related disorders. We compare and co...
Management Strategies for Plaque Psoriasis ACPE-Accredited*
17 Mar 2025
Contributed by Lukas
On this episode, we evaluate current guidelines and evidence-based treatment strategies for managing plaque psoriasis, including topical, systemic, an...
Managing COPD: 2025 GOLD Guidelines *ACPE-Accredited*
26 Feb 2025
Contributed by Lukas
On this episode, we review COPD and its clinical presentations, etiologies, pathophysiology, and management. We discuss the newly updated 2025 GOLD gu...
Managing Pulmonary Arterial Hypertension *ACPE-Accredited*
14 Feb 2025
Contributed by Lukas
On this episode, we evaluate current guidelines and evidence-based treatment strategies for managing pulmonary arterial hypertension. We compare and c...
Rheumatoid Arthritis: Treatment Strategies for 2025 * ACPE-Accredited *
28 Jan 2025
Contributed by Lukas
On this episode, we evaluate current guidelines and evidence-based treatment strategies for managing rheumatoid arthritis. We compare and contrast the...
Heart Failure Management: Current Strategies and Best Practices *ACPE-Accredited*
16 Jan 2025
Contributed by Lukas
On this episode, we evaluate current guidelines and evidence-based treatment strategies for managing heart failure (primarily focusing on HFrEF). We c...
Diabetes Management in 2025: ADA Guideline Updates *ACPE-Accredited*
31 Dec 2024
Contributed by Lukas
On this episodes, we review some of the key updates in the 2025 American Diabetes Association treatment guidelines and their implications for clinical...
Food Allergies and Celiac Disease: Managing Dietary Challenges *ACPE-Accredited*
19 Dec 2024
Contributed by Lukas
On this episode, we discuss define food allergies and describe their clinical presentations, underlying pathophysiology, and diagnostic criteria. We a...
Managing Atopic Dermatitis *ACPE-Accredited*
04 Dec 2024
Contributed by Lukas
On this episode, we evaluate the current guidelines and evidence-based treatment strategies for managing atopic dermatitis. We compare and contrast th...
Managing Allergic Rhinitis *ACPE-Accredited*
19 Nov 2024
Contributed by Lukas
On this episode, we discuss allergic rhinitis and describe its clinical presentations, common triggers, and pathophysiology. We compare and contrast t...
Opportunistic Infections in Immunocompromised Patients *ACPE-Accredited*
10 Nov 2024
Contributed by Lukas
On this episode, we discuss the prevention and management of opportunistic infections in patients with HIV and other immunocompromising conditions. We...
Managing Axial Spondyloarthritis *ACPE-Accredited*
25 Oct 2024
Contributed by Lukas
On this episode we discuss the diagnosis and management of axial spondyloarthritis. We begin by defining axial spondyloarthritis (radiographic axial...
Dermatophyte Infections *ACPE-Accredited*
09 Oct 2024
Contributed by Lukas
On this episode, we discuss dermatophyte infections. We review their clinical presentations, etiologies, and pathophysiology. We compare and contrast ...
Optimizing Crohn's Disease Management *ACPE-Accredited*
23 Sep 2024
Contributed by Lukas
On this episode, we discuss Crohn's disease. We describe the clinical presentations, etiologies, and the pathophysiology. We compare and contrast the...
Migraine Management: Up to Date Treatment Strategies *ACPE-Accredited*
10 Sep 2024
Contributed by Lukas
On this episode, we discuss the management of migraines. We begin with background info including clinical presentations, potential triggers, and patho...
Optimizing Asthma Care: Evidence-Based Approaches for 2024 *ACPE-Accredited*
27 Aug 2024
Contributed by Lukas
On this episode, we describe the clinical presentation, etiology, and pathophysiology of asthma. We review current guidelines and evidence-based treat...
Treating Opioid Use Disorder: Current Guidelines and Best Practices *ACPE-Accredited*
14 Aug 2024
Contributed by Lukas
On this episode we discuss the management of opioid use disorder. We begin by describing its clinical presentations, etiologies, and pathophysiology. ...
Hypertension Management Strategies in 2024 *ACPE-Accredited*
30 Jul 2024
Contributed by Lukas
On this episode, we review the treatment options and management strategies for primary hypertension. Cole and I are happy to share that our listener...
Endometriosis Management *ACPE-Accredited*
19 Jul 2024
Contributed by Lukas
On this episode, we discuss the management of endometriosis. We review some background information as well as the various treatment options and the tr...
Skin and Soft Tissue Infections *ACPE-Accredited*
03 Jul 2024
Contributed by Lukas
On this episode we discuss both purlent and non-purlent skin and soft tissue infections. We also use this episode to review various antimicrobial agen...
Managing Movement Disorders *ACPE-Accredited*
19 Jun 2024
Contributed by Lukas
On this episode, we discuss the management of a few different movement disorders. We review the pharmacotherapy options for restless leg syndrome, Tou...
Managing Epilepsy: Treatment Strategies and Clinical Considerations *ACPE-Accredited*
03 Jun 2024
Contributed by Lukas
On this episode, we discuss the various antiseizure medications used to manage a patient with Epilepsy. Cole and I are happy to share that our listene...
Patient Case: Sickle Cell Disease with Dr. Bernard Best
31 May 2024
Contributed by Lukas
On this episode, we are joined by Dr. Bernard Best, PharmD. We are discussing a complex patient case that focuses on sickle cel disease. You can find ...
Parkinson's Disease *ACPE-Accredited*
21 May 2024
Contributed by Lukas
On this episode, we discuss the management and treatment of Parkinson's Disease. Cole and I are happy to share that our listeners can claim ACPE-acc...
New Drugs of 2024 *ACPE-Accredited*
10 May 2024
Contributed by Lukas
On this episode, we discuss some of the new medications that were FDA approved in the first half of 2024. We discuss pivmecillinam (Pivya), ceftobipr...
Hormonal Contraception Pharmacotherapy *ACPE-Accredited*
25 Apr 2024
Contributed by Lukas
On this episode, we review various hormonal contraception options. We disucss the benefits and risks associated with different forms of estrogen and p...
2024 AAD Acne Treatment Guidelines *ACPE-Accredited*
10 Apr 2024
Contributed by Lukas
On this episode, we discuss the 2024 acne treatment guidelines that was published by the American Academy of Dermatology. This new set of guidelines w...
Managing Dry Eye Disease and Allergic Conjunctivitis *ACPE-Accredited*
26 Mar 2024
Contributed by Lukas
On this episode, we examine the management of dry eye disease and allergic conjunctivitis. It is important that pharmacists and nurses understand the ...
Healing Heartburn: An Approach to GERD Management *ACPE-Accredited*
05 Mar 2024
Contributed by Lukas
On this episode, we discuss the treatment options used for the managment of gastroesophageal reflux disease. We review various types of antacids, H2 b...
Treatment and Prevention of Hepatitis A and B Infections *ACPE-Accredited
25 Jan 2024
Contributed by Lukas
On this podcast we discuss the management of both hepatitis A and B. We review some background information as well as the criteria for a diagnosis of ...
High Science: The Medical Potential of THC, CBD, and Synthetics
20 Jan 2024
Contributed by Lukas
On this episode, we are joined by returning guest Dr. Kaleigh Steeleman. Kaleigh is currently a PGY-1 resident at Chaple Hill. She has spent some of h...
Diagnosis and Management of Lupus and Related Complications *ACPE-Accredited*
11 Jan 2024
Contributed by Lukas
On this episode we examine systemic lupus erythematosus (SLE). Lupus is a relatively uncommon condition, but is debilitating for those who suffer from...
Beyond the Beat: Exploring the 2023 A Fib Guidelines *ACPE-Accredited*
02 Jan 2024
Contributed by Lukas
On this episode, Cole and I review the 2023 updated atrial fibrillation guidelines. We discuss various rate-control and rythmn-control pharmacotherapy...
Curing Hep C: A Dive into Treatment Options *ACPE-Accredited*
12 Dec 2023
Contributed by Lukas
On this episode, we review the 2023 Hepatitis C Guidance that was recently published by the Infectious Diseases Society of America (IDSA) and the Amer...
2023 New Drug Approvals *ACPE-Accredited*
28 Nov 2023
Contributed by Lukas
On this episode, Cole and I review some of the medications that gained U.S. FDA approval in 2023. We cover a variety of medications that treat various...
Treatment of Acute Rhinosinusitis and Pharyngitis *ACPE-Accredited*
14 Nov 2023
Contributed by Lukas
On this episode, my good friend and colleague Alex Hovey, PA-C is sitting in for Cole this episode. We review the treatment of acute rhinosinusitis an...
Healing Hidden Wounds: Exploring PTSD Treatment *ACPE-Accredited*
02 Nov 2023
Contributed by Lukas
On this episode we review post-traumatic stress disorder (PTSD). We discuss some background information on the disease. Then, we review the various tr...
Exxua (gepirone): the newly approved antidepressant
25 Oct 2023
Contributed by Lukas
On this episode, we discuss the 5-HT1A receptor agonist, Exxua (gepirone). Exxua was recently FDA approved for the treatment of general depression. We...
Classification and Management of Chronic Kidney Disease *ACPE-Accredited*
17 Oct 2023
Contributed by Lukas
On this episode, we review the management of chronic kidney disease. We discuss when to use iron vs erythropoietin-stimulating agents (ESAs) for a pat...
Navigating the Urinary Maze: BPH, OAB, and the complexities of treatment when they coexist *ACPE-Accredited*
04 Oct 2023
Contributed by Lukas
On this episode we discuss the management of benign prostatic hyperplasia (BPH) as well as overactive bladder (OAB). We review alpha blockers, 5-alpha...
Treating UTIs *ACPE-Accredited*
20 Sep 2023
Contributed by Lukas
On this episode, we review the treatment of both uncomplicated and complicated urinary tract infections (UTIs). We also use this episode to refresh so...
High Powered Medicine Book Review
18 Sep 2023
Contributed by Lukas
On this episdoe, we are joined by Dr. Alex Poppen, PharmD, the author of High Powered Medicine. HPM is a book that summarizes over 150 landmark clinic...
Managing Gout *ACPE-Accredited*
11 Sep 2023
Contributed by Lukas
On this episode, we discuss both treating an acute gout flare and chronic management of gout. We discuss colchicine, NSAIDS, corticosteroids, canakinu...
Managing Osteoarthritis Pain *ACPE-Accredited*
21 Aug 2023
Contributed by Lukas
On this episode, we review pharmacotherapy options for managing osteoarthritis pain. We focus primarily on on hand, knee, and hip OA. We cover NSAIDS,...
A Review of Weight Loss Medications *ACPE-Accredited*
09 Aug 2023
Contributed by Lukas
On this episode, we review the medications that are FDA approved for weight loss. We also review recent data on high dose oral semaglutide and injecta...
Alteplase vs Tenecteplase for Ischemic Stroke
31 Jul 2023
Contributed by Lukas
On this episode, we are joined by Dr. Brian Gilbert, PharmD, BCCCP, FCCM, FNCS, to compare and contrast alteplase (tPA) versus tenecteplase (TNK-tPA) ...
Managing Hypothyroidism *ACPE-Accredited*
24 Jul 2023
Contributed by Lukas
On this episode, we review the management of hypothyroidism. We focus on levothyroxine as the foundation for a patient treatment. We also discuss the ...
Treating Community Acquired Pneumonia *ACPE-Accredited*
11 Jul 2023
Contributed by Lukas
On this episode, we discuss the various treatment options for community acquired pneumonia. We compare and contrast the differences in treating a pati...
Substance Use Disorder *ACPE-Accredited*
30 Jun 2023
Contributed by Lukas
On this episode, we discuss the management of substance use disorder. We review the pharmacotherapy/psychotherapy options for treating the abuse of al...
Smoking Cessation *ACPE-Accredited*
13 Jun 2023
Contributed by Lukas
On this episode, we discuss the pharmacotherapy options available for smoking cessation. We start with some background info including pathophysiology,...
Patient Case: Sickle Cell Disease, HFrEF, DM2, and More
08 Jun 2023
Contributed by Lukas
On this episode, we go over a pharmacotherapy plan for a patient with sickle cell disease, HFrEF, DM2, dyslipidemia, hypertension, POAG, dry eye dise...
A Closer Look at Managing Depression in Patients with Comorbidities *ACPE-Accredited*
30 May 2023
Contributed by Lukas
On this episode, we discuss the considerations and possible changes to a patient's general depression regimen when they have various comorbidities or ...
Preventing Recurrent C. diff Infections with Vowst
24 May 2023
Contributed by Lukas
On this episode, we discuss Vowst, the oral fecal microbiota product for preventing the recurrance of C. diff infection. We review Vowst's dosing, adm...
Osteoporosis Management *ACPE-Accredited*
15 May 2023
Contributed by Lukas
On this episode, we review the various pharmacotherapy options that are used in the management of osteoporosis. We go over bisphosphonates, denosumab,...
Managing Acne Vulgaris *ACPE-Accredited*
01 May 2023
Contributed by Lukas
On this episode, we compare and contrast the various pharmacotherapy options used to manage acne vulgaris. We review topical retinoids, topical and or...
A Review of Ulcerative Colitis *ACPE-Accredited*
21 Apr 2023
Contributed by Lukas
On this episode, we discuss the management of ulcerative colitis and review the various pharmacotherapy options that are currently available. Cole a...
Mixing Laughter and Medicine with the Glaucomfleckens
14 Apr 2023
Contributed by Lukas
On this episode, we are joined by Dr. Will Flanary (AKA Dr. Glaucomflecken) and Kristin Flanary (AKA Lady Glaucomflecken). Dr. Flanary is a practicing...
Management of Primary-Open Angle Glaucoma *ACPE-Accredited*
04 Apr 2023
Contributed by Lukas
On this episode, we review the pharmacotherapy options available for managing primary-open angle glaucoma. We discuss prostaglandin analogs, beta-bloc...
Managing Irritable Bowel Syndrome *ACPE-Accredited*
23 Mar 2023
Contributed by Lukas
On this episode, we discuss the management and treatment of irritable bowel syndrome (IBS). We review the various medications recommended published in...
Bempedoic Acid and the CLEAR Outcomes Trial
14 Mar 2023
Contributed by Lukas
On this episode, we review the recently published CLEAR-outcomes trial that was looking at bempedoic acid's (Nexletol) ability to lower the risk of CV...
Treatment and Management of Anemia *ACPE-Accredited*
06 Mar 2023
Contributed by Lukas
On this episode, we review the treatment and management of various types of anemia. We discuss iron-deficiency anemia, B-12 and folate dificiency anem...
ACP BP Goals, Ozempic Face, and Healthy Potatoes
28 Feb 2023
Contributed by Lukas
On this episode we cover three different topics that have been in the medical news lately. First, we compare/contrast the blood pressure goals that we...
A Review of Antipsychotics *ACPE-Accredited*
20 Feb 2023
Contributed by Lukas
On this episode we review typical (first generation) and atypical (second generation) antipsychotics. We discuss receptor signaling, various adverse e...
Does Morning or Bedtime Dosing of Antihypertensives Matter? *ACPE-Accredited*
06 Feb 2023
Contributed by Lukas
On this episode, we discuss dosing antihypertensives at bedtime compared to the morning and if it impacts patient outcomes. We review the MAPEC, Hygia...
New Year New Drugs: Leqembi, Airsupra, and Brenzavvy
31 Jan 2023
Contributed by Lukas
On this episode we discuss the new drugs that have been approved in 2023 so far. We review Leqembi (lecanemab-irmb) injection for Alzheimer's disease,...
Obsessive Compulsive Disorder *ACPE-Accredited*
23 Jan 2023
Contributed by Lukas
On this episode, we discuss the pharmacotherapy options for managing obsessive compulsive disorder (OCD). We based our discussion on the treatment alg...
2023 ADA Guideline Updates *ACPE-Accredited*
09 Jan 2023
Contributed by Lukas
On this episode, Cole and I review some of the updates that were published in the 2023 American Diabetes Association guidelines. Cole and I are happy ...
Patient Case: Bipolar Disorder and Epilepsy
06 Jan 2023
Contributed by Lukas
Below is the patient case information: 63-year-old white male. Problem List Bipolar II disorder Insomnia Epilepsy (tonic-clonic seizures) Dyslipidemia...
Insomnia Disorder *ACPE-Accredited*
27 Dec 2022
Contributed by Lukas
On this episode, we discuss the management of insomnia disorder. We review the criteria necessary for an insomnia disorder diagnosis. We then compare ...
Pharmacologic Options for Chronic Pain *ACPE-Accredited*
13 Dec 2022
Contributed by Lukas
On this episode, we discuss the various therapeutic options for managing a patient with chronic pain. We discuss nonpharmacological options, anti-infl...
Generalized Anxiety Disorder *ACPE-Accredited*
28 Nov 2022
Contributed by Lukas
On this episode, Cole and I review the published treatment algorithm created by Harmony Raylen Abejuela, MD and David Osser, MD. This was part of the ...
Our Thoughts on the Diuretic Comparison Project (DCP)
21 Nov 2022
Contributed by Lukas
On this episode, we review the results that have been reported from the Diuretic Comparison Project (DCP). The point-of-care clinical trial was lookin...
Comparison of Oral Medications for Type-2 Diabetes *ACPE-Accredited*
14 Nov 2022
Contributed by Lukas
On this episode, we compare and contrast oral medications that can be used to manage patients with type-2 diabetes. We review metformin, SGLT2 inhibit...
Updates in the Management of Amyotrophic Lateral Sclerosis
11 Nov 2022
Contributed by Lukas
On this episode, we review the management of amyotrophic lateral sclerosis (ALS). We discuss riluzole, edaravone, and sodium phenylbutyrate-taurursodi...
Chronic Coronary Syndromes *ACPE-Accredited*
31 Oct 2022
Contributed by Lukas
On this episode, we discuss chronic coronary syndromes, and we focus primarily on the treatment of acute episodes of angina. Cole and I are happy to...
Managing Atrial Fibrillation *ACPE-Accredited*
17 Oct 2022
Contributed by Lukas
On this episode, we discuss the management of acute and chronic atrial fibrillation. We review the various pharmacotherapy options, compare rate contr...
Celebrating Episode 200 with Dr. Wayne Weart
16 Oct 2022
Contributed by Lukas
We are joined by Dr. Wayne Weart to celebrate reaching our 200th episode. We discuss his career as a clinical pharmacist and educator and get his thou...
SGLT-2 Inhibitors in Heart Failure *ACPE-Accredited*
03 Oct 2022
Contributed by Lukas
On this episode, we review the data that lead to some SGLT-2 inhibitors being used routinely in heart failure. We discuss the initial cardiovascular s...
New Options for Managing Plaque Psoriasis
27 Sep 2022
Contributed by Lukas
On this episode, we discuss deucravacitinib tablets (Sotyktu), roflumilast cream (Zoryve), and tapinarof cream (Vtama). All three medications were app...