E12: PacBio ONSO | Sequencing by binding

Because only one type of nucleotide is not complicated enoughChapters:01:35 Introducing old problems15:30 More Phred, more better34:40 QuickGen: genetic testing47:40 Bioinformatics tools: samtoolsPacBio ONSO Specs: https://www.pacb.com/wp-content/uploads/Onso-specification-sheet.pdfSBB explained by PacBio: https://www.pacb.com/blog/sbb-sequencing/Why higher quality is better: https://pmc.ncbi.nlm.nih.gov/articles/PMC11331594/Short read sequencing market heating up: https://www.nature.com/articles/s41587-022-01632-4SBB for visual learners: https://www.youtube.com/watch?v=i_mSaNBOVmQSince 2018, West German Genome Center (https://wggc.de/)operates as the next generation sequencing facility and supports research in genomics & transcriptomics by providing expertise and sequencing services. WGGC is a part of the Next Generation Sequencing Competence Network (NGS-CN: https://ngs-kn.de/) - network of NGS core facilities in Germany. Listen to our podcast and we're happy to receive your feedback&questions via Email (podcast[dot]explain[at]gmail[dot]com ).License NoticeThis podcast including all episodes, unless otherwise noted, is licensed under a ⁠⁠⁠⁠Creative Commons Attribution 4.0 International License⁠⁠⁠⁠.You are free to share, remix, and use this content as long as you give appropriate credit, provide a link to the license, and indicate if changes were made.Attribution:Podcast Title: Explain PodcastCreators: Iuliia Novoselova, Daniel RickertWebsite: ⁠⁠⁠⁠https://ngs-cn.de/explain-podcast/⁠

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