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Foundation Fighting Blindness

Science

Episodes

Showing 101-200 of 242
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ARVO 2024 Highlight: PYC Reports Initial Clinical Trial Results for its RNA Therapy Targeting RP

16 May 2024

Contributed by Lukas

No serious adverse events were reported. One patient had encouraging improvement in retinal sensitivity.

ARVO 2024 Highlight: New Gene Linked to RP in People with African Ancestry

14 May 2024

Contributed by Lukas

The discovery will help geneticists diagnose more RP patients with African descent.

ARVO 2024 Highlight: Positive Two-Year Results from PDE6B Gene Therapy Clinical Trial

10 May 2024

Contributed by Lukas

Mutations in PDE6B are a leading cause of retinitis pigmentosa.

Eye on the Cure Podcast | Episode 65: Matthew Whitaker

03 May 2024

Contributed by Lukas

Matthew Whitaker talks to host Ben Shaberman about his remarkable achievements and success as a young jazz pianist and composer. Matthew was born thre...

Atsena’s XLRS Gene Therapy Shows Efficacy in Phase 1/2 Clinical Trial

02 May 2024

Contributed by Lukas

The XLRS gene therapy was well tolerated and resolved damaging schisis cavities in patients receiving the lowest dose.

SalioGen Developing Novel Gene Insertion Therapy for Stargardt Disease

19 Apr 2024

Contributed by Lukas

The company’s innovative Gene Coding™ platform enables seamless insertion of DNA into selective genomic locations.

Eye on the Cure Podcast | Episode 64: Dr. Kapil Bharti

16 Apr 2024

Contributed by Lukas

Kapil Bharti, PhD, a senior investigator and director of the Intramural Research Program at the National Eye Institute (NEI), talks with host Ben Shab...

Phase 3 Clinical Trial of NAC Launched for RP Patients

12 Apr 2024

Contributed by Lukas

The drug is thought to work independent of the mutated gene causing RP.

ViGeneron Launches Clinical Trial of Gene Therapy for RP Caused by CNGA1 Mutations

11 Apr 2024

Contributed by Lukas

The gene therapy is administered using a less-invasive intravitreal injection.

Ocugen to Launch Phase 3 Clinical Trial of Modifier Gene Therapy for RP

08 Apr 2024

Contributed by Lukas

The emerging treatment is designed to work independent of the patient’s mutated gene.

Nanoscope Plans to Apply for FDA Approval for its Optogenetic Therapy

27 Mar 2024

Contributed by Lukas

The company reported positive two-year results for its Phase 2 clinical trial of MCO-010.

Opus Reports Vision Improvements for Patients in LCA5 Gene Therapy Clinical Trial

26 Mar 2024

Contributed by Lukas

Opus Reports Vision Improvements for Patients in LCA5 Gene Therapy Clinical Trial by Foundation Fighting Blindness

Eye on the Cure Podcast | Episode 63: Dr. Hema Ramkumar

08 Mar 2024

Contributed by Lukas

Hema Ramkumar, MD, a retinal specialist, surgeon, and founder of the company Oculogenex, talks with host Ben Shaberman about her emerging therapy that...

Eye on the Cure Podcast | Episode 62: Dr. Peter Quinn

23 Feb 2024

Contributed by Lukas

Peter Quinn, PhD, a principal investigator and associate research scientist at Columbia University, talks to host Ben Shaberman about the promise of e...

jCyte Announces Plans to Launch Phase 3 Clinical Trial of Cell Therapy for RP

21 Feb 2024

Contributed by Lukas

Known as retinal progenitors, the company’s jCells® are designed to preserve photoreceptors in people with retinitis pigmentosa (RP) and other reti...

Beacon Therapeutics Reports Encouraging Interim Results from Phase 2 Clinical Trial for XLRP

09 Feb 2024

Contributed by Lukas

Beacon Therapeutics has reported vision improvements for five of eight patients receiving the high dose of its X-linked retinitis pigmentosa (XLRP) ge...

Eye on the Cure Podcast | Episode 61: Dr. Jose Sahel

02 Feb 2024

Contributed by Lukas

Dr. Jose Sahel, one of the most honored and accomplished leaders in the retinal disease research space, talks with host Ben Shaberman about his establ...

Ascidian to Launch Clinical Trial for Stargardt Disease RNA Editing Therapy

01 Feb 2024

Contributed by Lukas

ACDN-01 is the only genetic medicine entering clinical development for Stargardt disease.

Eye on the Cure Podcast | Episode 60: Justin Kauflin

19 Jan 2024

Contributed by Lukas

Justin Kauflin, a renowned jazz pianist who lost his vision as a boy, talks to host Ben Shaberman about his extensive touring, numerous collaborations...

Eye on the Cure Podcast | Episode 59: Dr. Robert MacLaren

05 Jan 2024

Contributed by Lukas

Dr. Robert MacLaren, a world-renowned retinal surgeon, clinical trial investigator, and research lab leader at the University of Oxford, talks to host...

Eye on the Cure Podcast | Episode 58: Jason Comander, MD, PhD

15 Dec 2023

Contributed by Lukas

Jason Comander, MD, PhD, clinical researcher, surgeon, and director of the Inherited Retinal Disease Disorders Service at Mass Eye and Ear, talks to h...

Théa Completes Acquisition of ProQR’s LCA10 and USH2A Treatment Programs

11 Dec 2023

Contributed by Lukas

Known as antisense oligonucleotides, the treatments performed encouragingly in ProQR’s clinical trials

Eye on the Cure Podcast | Episode 57: James Rath

01 Dec 2023

Contributed by Lukas

James Rath, a renowned filmmaker and accessibility consultant, talks to host Ben Shaberman about his vision loss journey and travel documentary, Blind...

Eye on the Cure Podcast | Episode 56: Michael Voevodsky, MBA, CEO

10 Nov 2023

Contributed by Lukas

Michael Voevodsky, MBA, CEO at MitoChem Therapeutics, talks to host Ben Shaberman about his company's emerging, gene-agnostic treatment designed to b...

Kiora Reports Vision Restoration in Phase 1/2 Clinical Trial for Photoswitch Therapy

08 Nov 2023

Contributed by Lukas

The company’s molecule is designed to restore some vision to people with ultra-low or no vision caused by advanced retinitis pigmentosa and other re...

New Report: Vitamin A Supplementation Provides No Vision Benefit to RP Patients

02 Nov 2023

Contributed by Lukas

The report also concludes that vitamin E supplementation accelerates vision loss for RP patients.

Eye on the Cure Podcast | Episode 55: Omar Mahroo, MB, PhD

13 Oct 2023

Contributed by Lukas

Omar Mahroo, MB, PhD, talks with host Ben Shaberman about electrophysiological testing for the retina, namely the electroretinogram (ERG), and its imp...

Eye on the Cure Podcast | Episode 54: Rachelle Lin, OD, MS, FAAO

29 Sep 2023

Contributed by Lukas

Rachelle Lin, OD, MS, FAAO, an optometrist and assistant professor at the Southern California College of Optometry at Marshall B. Ketchum University, ...

Ocugen Reports Updated Results for Clinical Trial of Modifier Gene Therapy

18 Sep 2023

Contributed by Lukas

Ocugen Reports Updated Results for Clinical Trial of Modifier Gene Therapy by Foundation Fighting Blindness

Eye on the Cure Podcast | Episode 53: David Birch, PhD

15 Sep 2023

Contributed by Lukas

David Birch, PhD, at the Retina Foundation of the Southwest in Dallas, talks to host Ben Shaberman about his productive and impactful 40-plus-year car...

First Patient Dosed in LCA5 Gene Therapy Clinical Trial Launched by Opus Genetics

07 Sep 2023

Contributed by Lukas

Opus was established by the RD Fund, the Foundation’s venture philanthropy arm

Eye on the Cure Podcast | Episode 52: Brendan Creemer

01 Sep 2023

Contributed by Lukas

September 1, 2023. Brendan Creemer talks to host Ben Shaberman about how he is taking on the diagnosis of Usher syndrome 1F by dedicating his educatio...

SparingVision Recruiting for Clinical Trial of Cone-Preserving Gene Therapy for RP

31 Aug 2023

Contributed by Lukas

First cohort of patients has been dosed in Phase 1/2 clinical trial taking place in Pittsburgh and Paris

Atsena Doses First Patient in XLRS Gene Therapy Clinical Trial

28 Aug 2023

Contributed by Lukas

The AAV.SPR gene delivery system used in the trial is designed to more safely reach targeted retinal cells

Théa Acquires ProQR’s LCA10 and USH2A Treatment Programs, Plans to Continue Clinical Development

25 Aug 2023

Contributed by Lukas

Known as antisense oligonucleotides, the treatments performed encouragingly in ProQR’s clinical trials

Eye on the Cure Podcast | Episode 51: Artur Cideciyan, PhD

18 Aug 2023

Contributed by Lukas

Artur Cideciyan, PhD, one of the world’s foremost authorities in measuring vision and structural changes in people with retinal diseases, talks with...

Eye on the Cure Podcast | Episode 50: Rachel Huckfeldt, MD, PhD

21 Jul 2023

Contributed by Lukas

Rachel Huckfeldt, MD, PhD, a clinical researcher and assistant professor of ophthalmology at Mass Eye and Ear, talks with host Ben Shaberman about car...

PYC Doses First Patient in Clinical Trial of RNA Therapy for RP11 (PRPF31 Mutations)

12 Jul 2023

Contributed by Lukas

The emerging RNA therapy is designed to boost expression of the PRPF31 protein

Eye on the Cure Podcast | Episode 49: Alex Cohen, PhD

30 Jun 2023

Contributed by Lukas

Alex Cohen, PhD, a marketing professor with retinitis pigmentosa, talks with host Ben Shaberman about his career in the hospitality industry and launc...

Eye on the Cure Podcast | Episode 48: Jami Kern, PhD

16 Jun 2023

Contributed by Lukas

Jami Kern, PhD, chief clinical officer at Nacuity Pharmaceuticals, talks with host Ben Shaberman about NACA, the company's emerging gene-agnostic ther...

Eye on the Cure Podcast | Episode 47: Kari Branham

02 Jun 2023

Contributed by Lukas

Kari Branham, a genetic counselor with Kellog Eye Center at the University of Michigan, talks to host Ben Shaberman about a variety of topics related ...

Coave Reports Encouraging Phase 1/2 Clinical Trial Results for PDE6B Gene Therapy

01 Jun 2023

Contributed by Lukas

The company is expanding the trial to enroll younger patients with less advanced disease

Eye on the Cure Podcast | Episode 46: Aaron Osborne, MD

19 May 2023

Contributed by Lukas

Aaron Osborne, MD, chief medical officer and chief development officer at Nanoscope Therapeutics, talks about vision restoration in clinical trials of...

Atsena Receives FDA Authorization to Launch a Gene Therapy Clinical Trial for XLRS

02 May 2023

Contributed by Lukas

Known as The Lighthouse Study, the Phase 1/2 trial is expected to begin in mid-2023

Eric Pierce Receives Proctor Medal for Outstanding Achievements in Retinal Research

01 May 2023

Contributed by Lukas

During his Proctor Award Lecture, Dr. Pierce reviewed encouraging clinical trial results for Editas’ CRISPR/Cas9 treatment for people with LCA10

News | Budd Tucker Honored with Award for Advancements in Retinal Therapy Development

28 Apr 2023

Contributed by Lukas

News | Budd Tucker Honored with Award for Advancements in Retinal Therapy Development by Foundation Fighting Blindness

Eye on the Cure Podcast | Episode 45: Henry Klassen, MD, PhD

28 Apr 2023

Contributed by Lukas

April 28, 2023. Henry Klassen, MD, PhD, co-founder of jCyte and clinical researcher at UC Irvine, talks to host Ben Shaberman about jCyte's clinical t...

News | Bionic Sight Reports Vision Improvements for RP Patients in its Emerging Optogenetic Therapy

20 Apr 2023

Contributed by Lukas

Clinical trial participants with advanced vision loss from RP were able to identify fruits and vegetables

Eye on the Cure Podcast | Episode 44: Jason Taylor

14 Apr 2023

Contributed by Lukas

April 14, 2023. Electronica musician and composer Jason Taylor, aka Aether, talks with podcast host Ben Shaberman about his craft, inspirations, and h...

Eye on the Cure Podcast | Episode 43: Marinna Madrid, PhD

31 Mar 2023

Contributed by Lukas

March 31, 2023. Marinna Madrid, PhD, co-founder and chief product officer at Cellino, talks about her groundbreaking work in developing lasers as a do...

News | Vision Improvements Reported for RP Patients in Phase 2B Nanoscope Clinical Trial

30 Mar 2023

Contributed by Lukas

Most participants with advanced retinitis pigmentosa (RP) in the trial had improved navigation and/or object discrimination in reduced lighting condit...

Eye on the Cure Podcast | Episode 42: Paul Bresge

10 Mar 2023

Contributed by Lukas

March 10, 2023. Paul Bresge, chief executive officer at Ray Therapeutics, talks to host Ben Shaberman about his company’s emerging optogenetic thera...

Eye on the Cure Podcast | Episode 41: Dean Bok, PhD

24 Feb 2023

Contributed by Lukas

February 24, 2023. Dean Bok, PhD, a distinguished professor and renowned researcher at UCLA, talks with host Ben Shaberman about his pivotal discovery...

Eye on the Cure Podcast | Episode 40: Rebecca Alexander

10 Feb 2023

Contributed by Lukas

February 10, 2023. Rebecca Alexander — a psychotherapist, keynote speaker, author, fitness instructor, and disability rights advocate — talks cand...

Eye on the Cure Podcast | Episode 39: Paul Bernstein, MD, PhD

20 Jan 2023

Contributed by Lukas

January 20, 2023. Paul Bernstein, MD, PhD, from the Moran Eye Center, University of Utah, and a member of the Foundation’s Scientific Advisory Board...

Eye on the Cure Podcast | Episode 38: Ben Shaberman

06 Jan 2023

Contributed by Lukas

January 6, 2023. For the first Eye on the Cure episode for 2023, host Ben Shaberman highlights some of the promising clinical advancement made in ther...

Eye on the Cure Podcast | Episode 37: Rando Allikmets, PhD

16 Dec 2022

Contributed by Lukas

December 16, 2022. Rando Allikmets, PhD, from Columbia University, talks to host Ben Shaberman about his remarkable and serendipitous discovery more t...

SparingVision Receives Authorization to Launch US Clinical Trial for its Cone-Preserving Treatment

02 Dec 2022

Contributed by Lukas

The emerging therapy is designed to work independent of the mutated gene causing retinitis pigmentosa

News | Opus Genetics to Launch Gene Therapy Clinical Trial for LCA5 Patients

02 Dec 2022

Contributed by Lukas

The LCA5 gene therapy will be the first emerging Opus treatment to move into a human study

Eye on the Cure Podcast | Episode 36: Sue Bramhall

02 Dec 2022

Contributed by Lukas

December 2, 2022. Host Ben Shaberman interviews Sue Bramhall who launched Mind's Eye Travel to host journeys around the world for people with vision l...

Eye on the Cure Podcast | Episode 35: Kenji Fujita, MD

18 Nov 2022

Contributed by Lukas

November 18, 2022. Kenji Fujita, MD, chief medical officer at Atsena Therapeutics, talks to host Ben Shaberman about retinal disease gene therapies in...

Editas Reports Results for 14 Participants in its Phase 1/2 CRISPR/Cas9 Clinical Trial for LCA10

18 Nov 2022

Contributed by Lukas

The company is seeking a partner to move the LCA10 program forward

Eye on the Cure Podcast | Episode 34: LambdaVision

04 Nov 2022

Contributed by Lukas

November 4, 2022. In this episode of Eye on the Cure, host Ben Shaberman talks with LambdaVision's Nicole Wagner, PhD, and Jordan Greco, PhD, about th...

#ShareYourVision | Advice for the Newly Diagnosed

30 Oct 2022

Contributed by Lukas

A blinding disease diagnosis can be overwhelming. Some good advice can go a long way. Do you have any advice for someone newly diagnosed? #ShareYourVi...

#ShareYourVision | How to Assist a Visually Impaired Person

28 Oct 2022

Contributed by Lukas

Ask. Questions. #ShareYourVision to tell others how to best support you. Learn more about how you can #ShareYourVision at: www.FightingBlindness.org/...

#ShareYourVision Story: Monica Pruitt

27 Oct 2022

Contributed by Lukas

Monica Pruitt shares her #ShareYourVision story about being diagnosed with Usher syndrome.

#ShareYourVision Story: Dan Day

26 Oct 2022

Contributed by Lukas

Dan Day shares his #ShareYourVision story about being diagnosed with retinitis pigmentosa.

#ShareYourVision | Strange Interactions

26 Oct 2022

Contributed by Lukas

Raise your hand if you have a strange experience to talk about. #ShareYourVision

#ShareYourVision | Blindness Is a Spectrum

24 Oct 2022

Contributed by Lukas

Blindness is not a complete blackout for everyone; it's a spectrum. What does blindness mean to you? #ShareYourVision this October. Learn more at: www...

#ShareYourVision | The Role Foundation Fighting Blindness Has In Their Lives

20 Oct 2022

Contributed by Lukas

Individuals sit in front of a black background and share about how others can best help them as part of our #ShareYourVision campaign. Learn more abou...

#ShareYourVision Story: Jake Ellis

18 Oct 2022

Contributed by Lukas

Jake shares his #ShareYourVision story about being diagnosed with Usher syndrome.

#ShareYourVision Story: Chad Bouton

16 Oct 2022

Contributed by Lukas

Chad shares his #ShareYourVision story about being diagnosed with retinitis pigmentosa.

#ShareYourVision | Questions We're Tired of Being Asked

15 Oct 2022

Contributed by Lukas

What's one question you're tired of being asked?

#ShareYourVision Story: Raquel

14 Oct 2022

Contributed by Lukas

Raquel shares her #ShareYourVision story about being diagnosed with retinitis pigmentosa.

#ShareYourVision | Creative Hacks for Living with Vision Loss

13 Oct 2022

Contributed by Lukas

Ya gotta do what ya gotta do! Now it’s your turn – what do YOU do?

#ShareYourVision Story: JJ Martinez

12 Oct 2022

Contributed by Lukas

JJ Martinez shares her #ShareYourVision story about being diagnosed with retinitis pigmentosa.

#ShareYourVision | The Positives & Negatives of Going Blind

12 Oct 2022

Contributed by Lukas

"If you never had to do anything hard, you would never learn how creative, strong, assertive, resilient you are." What have you learned about yourself...

#ShareYourVision Story: Brett Knight

11 Oct 2022

Contributed by Lukas

Brett Knight shares his #ShareYourVision story about being diagnosed with retinoschisis.

#ShareYourVision Story: Martha Steel

10 Oct 2022

Contributed by Lukas

Martha Steel shares her #ShareYourVision story about being diagnosed with Usher syndrome.

#ShareYourVision | First Time Meeting Another Blind Person

10 Oct 2022

Contributed by Lukas

To help spread awareness during October Blindness Awareness Month, we’re inviting you to share your vision-loss journey through written word, audio ...

#ShareYourVision | Why It's Important to Share Your Vision Story

05 Oct 2022

Contributed by Lukas

To help spread awareness during October Blindness Awareness Month, we’re inviting you to share your vision-loss journey through written word, audio ...

Eye on the Cure Podcast | Episode 33: Jacque Duncan, MD

04 Oct 2022

Contributed by Lukas

October 7, 2022. Podcast host Ben Shaberman talks with Jacque Duncan, MD, a retinal specialist and clinical researcher at UCSF and chair of the Founda...

News | Atsena’s LCA-GUCY2D Gene Therapy Improves Vision in Phase 1/2 Clinical Trial

03 Oct 2022

Contributed by Lukas

The company is planning to move the emerging treatment into a pivotal trial

#ShareYourVision | Blindness Is...

03 Oct 2022

Contributed by Lukas

To help spread awareness during October Blindness Awareness Month, we’re inviting you to share your vision-loss journey through written word, audio ...

#ShareYourVision Story: Michelle Glaze

29 Sep 2022

Contributed by Lukas

Michelle Glaze shares her #ShareYourVision story about being diagnosed with retinitis pigmentosa.

Eye on the Cure Podcast | Episode 32: Dr. Sandy Greenberg

23 Sep 2022

Contributed by Lukas

September 23, 2022. Dr. Sandy Greenberg talks to host Ben Shaberman about his incredible life's journey of going blind suddenly at the age of 19 to ea...

Eye on the Cure Podcast | Episode 31: Jean Bousquet

09 Sep 2022

Contributed by Lukas

September 9, 2022. Jean Bousquet, a certified orientation and mobility specialist with the Office of Rehabilitation Services in Rhode Island, talks to...

News | Belite Bio Launching Phase 3 Clinical Trial for Stargardt Disease Drug

29 Aug 2022

Contributed by Lukas

The company’s drug is designed to reduce accumulation of toxins that cause vision loss.

Eye on the Cure Podcast | Episode 30: Steven McCoy

19 Aug 2022

Contributed by Lukas

Host Ben Shaberman talks with Steven McCoy, who overcame early challenges as a kid with Usher syndrome, to become the first black, deaf-blind journali...

Eye on the Cure Podcast | Episode 29: David Gamm, MD, PhD

05 Aug 2022

Contributed by Lukas

August 5, 2022. Stem cell expert David Gamm, MD, PhD, talks with host Ben Shaberman about his innovative work in stem cell therapy development for ret...

Eye on the Cure Podcast | Episode 28: Brian Strem, PhD

22 Jul 2022

Contributed by Lukas

July 22, 2022. Brian Strem, PhD, CEO of Kiora Pharmaceuticals, talks to Ben Shaberman about his company's emerging gene-agnostic small molecule for re...

Eye on the Cure Podcast | Episode 27: Jeff Stern and Sally Temple

08 Jul 2022

Contributed by Lukas

July 8, 2022. Jeff Stern, MD, PhD, and Sally Temple, PhD, co-founders of the Neural Stem Cell Institute, talk with host Ben Shaberman about their disc...

VISIONS 2022 | Your Journey Toward Independent Mobility

07 Jul 2022

Contributed by Lukas

Speakers: Bill and Colleen Carty

VISIONS 2022 | Clinical & Research Updates: Age-Related Macular Degeneration (AMD)

07 Jul 2022

Contributed by Lukas

Speaker: Cathy Bowes Rickman, PhD and James Handa, MD

VISIONS 2022 | Clinical & Research Updates: Rare IRDs

07 Jul 2022

Contributed by Lukas

Achromatopsia, Choroideremia, Blue Cone Monochromacy, Cone-rod Dystrophy and X-linked Retinoschisis. Speakers: Christine Kay, MD and Robert Hufnagel, ...

VISIONS 2022 | Clinical & Research Updates: Retinitis Pigmentosa (RP)

07 Jul 2022

Contributed by Lukas

Speakers: Rachel Huckfeldt, MD, PhD and Jami Kern

VISIONS 2022 | Clinical & Research Updates: Usher Syndrome

07 Jul 2022

Contributed by Lukas

Speakers: Astra Dinculescu, PhD and Jacque Duncan, MD

VISIONS 2022 | Living Life To the Fullest: How Low Vision Occupational Therapy Can Help

07 Jul 2022

Contributed by Lukas

Speaker: Dana Aravich MS, OTR/L

VISIONS 2022 | Blind Athletes Breaking Barriers

07 Jul 2022

Contributed by Lukas

Speakers: Justin Bishop and Becca Meyers

VISIONS 2022 | RD Fund Biotech Overview

07 Jul 2022

Contributed by Lukas

Speaker: Rusty Kelley, PhD, MBA

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