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Chapter 1: What is the main topic discussed in this episode?
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This is the Global News Podcast from the BBC World Service. I'm Janet Jalil, and in the early hours of Tuesday, the 21st of April, these are our main stories. Mixed signals from Iran and the US as uncertainty continues over whether planned peace talks in Pakistan will go ahead. Apple's chief executive, Tim Cook, is stepping down.
We'll look at his legacy and tell you about the new man who's replacing him. The American singer, David, pleads not guilty to the murder of a 14-year-old girl whose remains were found in his car. Also in this podcast... She is doing fantastic.
She hiked up Mount Etna last year to celebrate her 50th wedding anniversary. She is a picture of vibrancy.
A new vaccine against pancreatic cancer gives hope to patients. With less than 48 hours to go as we record this podcast before the ceasefire deal between the US and Iran expires, it's still not clear whether peace talks between them will go ahead. In Pakistan's capital, Islamabad, roadblocks are in place and key sections of the city have been sealed off in anticipation of a meeting.
But Iran has yet to officially commit to more talks. Its chief negotiator, Mohammad Bagha Khalibaf, said Tehran would not accept discussions under the shadow of U.S. threats. However, our correspondent in Tehran, Lise Doucette, says there are growing indications that the Iranians will go.
There's still radio silence from Iranian officials about whether they will go to Islamabad for a second round of high-level, high-stakes negotiations. But with every hour that passes, there is a growing sense that the talks will take place. Iranians have to make their point. that the Iranian officials hadn't actually made a decision about going as long as the U.S. naval blockade was in force.
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Chapter 2: What are the latest developments in US-Iran peace talks?
And the US also wants Iran to hand over its stockpile of enriched uranium, which is something that Iran has declared a non-starter. The Iranians are seeking a pledge from the United States and Israel that the conflict won't resume. It wants reparations for damages caused by the war and relief from long-running sanctions.
And, of course, on Sunday, President Trump again warned that the United States would destroy every bridge and power plant in Iran if it rejected the United States terms. David Willis. Meanwhile, in southern Lebanon, an image of an Israeli soldier hitting a statue of Jesus with a sledgehammer has been widely condemned after it was shared online.
Israel's Prime Minister Benjamin Netanyahu says he's stunned and saddened by the incident and has promised that the military will take appropriately harsh disciplinary action. Yoland Nel in Jerusalem told us more.
The Israeli Prime Minister was quick to come out with his comments in English on his ex-account, I think understanding very well the international damage that this could do, this photo that's been shared widely on social media over the past couple of days.
The Israeli army has confirmed it's a soldier who is at the moment in southern Lebanon or has been in southern Lebanon in recent days. He's holding what appears to be a sledgehammer or an axe poised just over the face of this statue of Jesus on a crucifix that's been toppled. The understanding is that this is in the village of Dabal, which is in southern Lebanon, a Maronite Christian village.
This was a family's own shrine on the edge of their land, at the edge of the village.
It's not clear exactly at the moment what damage was ultimately done, but the Israeli army is saying that they will... help the Christian community there to repair this statue. The foreign minister of Israel, Gideon Saar, came out and said that he apologised for this incident and to every Christian who had been hurt by it and their feelings.
So you can see that this has really sort of, you know, had a big effect and that the local priest there told the BBC in Beirut that this was a desecration of
and really extremely upsetting for the Christian community in southern Lebanon, in this wide area which is currently occupied by Israeli forces, thousands of Israeli forces on the ground there. They see this as being a stronghold for the Shiite Muslim group Hezbollah. Yolande Nell.
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Chapter 3: What challenges are Iran's negotiators presenting to the US?
Can he make this a culturally relevant company once again?
And how is this going down in the tech world?
It is a very big deal. I mean, Apple is such a force in Silicon Valley. So anytime you see a transition like this, people are talking about it. And people have been talking about it for several months as we've seen some pretty high level departures at the company. So we kind of knew this was coming. But this is a guy who is young, 50 years old. He has spent basically half of his life at Apple.
So he's been there a long time. And I think people don't know him that well. You know, he's not a household name yet. Maybe he will be in two, three years time. But I think people are going to be watching here in Silicon Valley to see if he is somebody who is decisive, who will make big, bold moves. And they want to see those early on.
Lily Jamali. Pancreatic cancer is one of the deadliest types of cancer, in large part because symptoms often don't show up until it's too late. Only around a quarter of patients live for a year after diagnosis, and just one in ten survive for two years. But now an experimental vaccine developed by scientists in New York is offering a glimmer of hope.
It works by training the patient's own immune system to target the cancer ā And so far, it's shown striking results in a small group of patients, with most of them still alive more than five years on. My colleague Paul Henley spoke to Dr Vinod Balachandran, who's leading the trial at the Memorial Sloan Kettering Cancer Center in New York.
When we think of vaccines, we think of vaccines for infectious diseases. In that scenario, what you're doing is you're teaching the immune system to recognize a virus or a bacteria that has yet to infect your body. The majority of cancer vaccines are used as a therapy. Most of them are given to patients who have cancer in some way or form with an intent to treat their cancer.
In this particular scenario, we use the vaccines to teach the immune system to recognise pancreatic cancers in an effort to prevent their reoccurrence after surgery. And they're described as personalised. What does that mean?
Personalized refers to the fact that each individual patient's cancer vaccine is custom designed for that individual based upon individual genetic analysis of their tumor as well as genetic characteristics of the patient. Why is pancreatic cancer such a killer? The figures are terrible for survival as they stand, aren't they?
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Chapter 4: How is the US preparing for potential peace negotiations in Pakistan?
They started beating him up. He started bleeding for two hours, calling for medical treatment, but no one gave him any medical treatment. Do you ever get to speak to him? And he has no visitors in prison other than these visits by his lawyer?
The Israeli prison service says that all the allegations you've just quoted are false and baseless. You dismiss their version of events, do you?
Let them get humanitarian organisations, international lawyers. Let them send anyone if they're claiming that they're baseless. Why do they prevent them from seeing anyone?
They claim that all cases of systematic abuse on their part are baseless and that any individual misconduct is always investigated.
That's laughable for me. They have killed more than 100 Palestinian political prisoners only in the last two years.
From your point of view, why is your father in prison? Why do you think he's locked up?
Because they don't want Palestinian representation that is respected by the whole world. They don't want someone who is capable of unifying the Palestinian people towards a political vision. And because he supports the two-state solution.
Specifically, he was charged with 26 charges of murder and attempted murder stemming from attacks carried out by a group that he led.
Yeah, but it's very important to show by whom, by the occupation itself. So the occupation judicial system is a tool of the occupation.
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