Great Company with Jamie Laing
Dr Federica Amati: What Alcohol is Really Doing to Your Body | GREAT MOMENTS
26 Jan 2026
Chapter 1: What insights does Dr. Federica Amati share about alcohol's impact on health?
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Hello everyone, I'm Jamie Lang and this is Great Moments. In terms of chronic disease, so I get it, you know, smoking, not good. Alcohol, sure, yeah, not good. And I want to ask about alcohol, I want to get into that. The other thing, not moving, not exercising, we understand. Those are the sort of ones, they're the big hitters. What are the hidden ones that we don't really know?
And what are the unhealthy food habits that we're not sure about as well?
Okay, I think they're the big hitters, but how many people still smoke? would say a lot quite a lot and vaping not safe like is it better than smoking cigarettes sure should we do it no so so like it seems obvious but people still walk around smoking and vaping and so even though that's like the one well everyone knows that one it's like yeah but But have you ever smoked? In the past, I did.
My boyfriend smoked.
Did I know what I know now?
No, not so much. And also, I'm not defending this at all, actually. But since then, the smoking ban has come in. Since then, it feels like public health understanding of how bad smoking is has improved. And it's true also that younger people are smoking less now. So statistically, it's a trend, which is great.
And drinking less alcohol.
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Chapter 2: How is alcohol linked to breast cancer risk?
And when you look, I try to predict, how could you predict patient outcomes? Like, what is it about the people coming into the services that could help us understand whether they're likely to recover or not? That was my question. And the answers were various, but one of them is basically you can't take context away.
So if somebody comes into a mental health service and they have no access to housing and they can't get nutritious food every day and they have lived a trauma. then we can give the best cognitive behavior therapy there is, and they'll improve. But they're not going to be undepressed. They're not going to suddenly go below threshold because we've delivered a good service. There's context.
Context is always king, right? So whilst we try to understand how to improve people's health, and mental health is huge and it's such an important topic, We have to understand that we need to treat people as a whole. So patient-centered care, that's actually what my master's dissertation was in for public health.
Patient-centered care predicts how well people will recover from an illness or feel better. Because when you address the entire person as a whole, they're much more likely to be able to feel better and to improve their health on the whole picture, not just one thing. So, of course, I'm not suggesting that if you cut your wrist, then, yeah, you just treat the cut.
But when we're talking about these issues that impact our quality of life, like mental health does, it's not only does diet impact the likelihood of us losing
having mental health issues but if you suffer with mental health you're also going to make different dietary choices because cooking up a delicious meal that's really nutritious when you have severe depression is super hard because you don't have any energy you don't want to get out of bed let alone cook up a feast so yes um so there's this really one of the seminal trials on this is called the smiles trial and it was run by professor felice jacker in australia
And it took her ages to even get funding to recruit the patients for this because no one believed it would work. She wanted to see what happened if you had a group of patients with resistant depression. So these are patients who've had CBT. They've also got sometimes pharmacotherapy, so drugs. And she wanted to see if she could make a difference by changing their diets.
And they ran the trial and it was randomized. So she didn't know when she got the data and they analyzed it. They didn't know which group was which. And when she first ran it, she thought they'd switched the groups by mistake because it was such a change.
Get out of here.
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