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Ground Truths

Jennifer Gunter & Eric Topol - Discuss Women’s Health and Recent Changes by FDA for MHT

28 Nov 2025

Transcription

Full Episode

0.031 - 33.951 Eric Topol

So let me introduce the person who I have just a real pleasure, privilege to interview today. I have a conversation with Dr. Jen Gunter. She is a gynecologist, OB-GYN in Kaiser, Northern California. And she's been in the US for a few decades. She has two New York Times bestselling books. That's a big accomplishment on top of her career. She has a blog. Vagenda, which is phenomenal on Substance.

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34.533 - 45.778 Eric Topol

And she's out there as one of the great truth tellers in medicine, in particular, and this topic. She's been my go-to source for years. So welcome, Jen.

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46.319 - 48.043 Jennifer Gunter

Thank you. Thank you so much for having me.

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48.445 - 69.306 Eric Topol

Oh, this is really a delight. And so I thought we'd start because just two weeks ago was a big day in the world of MHT. Uh, and this was when there was a wall street journal editorial by Marty McCary, the FDA commissioner, and also simultaneously a JAMA paper, um,

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69.826 - 88.712 Eric Topol

And so I just was gonna start by reading, obviously it was a big deal to have the black box from 2003 taken away, but there were a couple of statements I wanted to get your reaction to. The first was in the liberation editorial that Marty wrote. He said, in my professional opinion,

88.692 - 106.363 Eric Topol

The demonization of hormone replacement therapy for perimenopausal women and the undercreation of its health benefits ranks among the greatest mistakes of modern medicine. And then the other one in JAMA, which is kind of in the same category,

106.343 - 122.023 Eric Topol

With the exception of antibiotics and vaccines, there may be no medication in the modern world that can improve the health outcomes of older women on a population level more than hormone therapy. What did you think about that?

122.307 - 142.054 Jennifer Gunter

Well, I would say that Marty McCary is an incredible cherry picker and really displays a lack of breadth of knowledge of women's health care in general, or I would say even like health care in general. Because, you know, if the data were that clear, if it was that thing, you know...

142.034 - 157.128 Jennifer Gunter

Why do all the professional societies who have people who do the research and who have combed through everything and disclosed their biases, why do they have different conclusions? And so I think that, yeah, I mean, that was just propaganda.

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