Habits and Hustle
Episode 444: The GLP-1 Triple Threat: Maximizing Benefits with Hormones, Strength Training, and Proper Dosing
Fri, 25 Apr 2025
Listen to the full episode here: https://podcasts.apple.com/us/podcast/habits-and-hustle/id1451897026?i=1000674829479 Ever wondered if you're truly maximizing the benefits of your GLP-1 medication? In this Fitness Friday episode on the Habits and Hustle podcast, I talk with Dr. Tyna Moore to discuss getting the most out of GLP-1s like Ozempic - especially for women approaching or experiencing menopause. We dive into how to determine the right GLP-1 dosage for your body, why strength training is non-negotiable when taking these medications the surprising connections between hormones, pain management, and joint health. Dr. Tyna is an expert in holistic regenerative medicine and resilient health with nearly three decades of experience in the medical world. Dr. Tyna brings a unique perspective to building robust health foundations, having graduated from the National College of Natural Medicine and the University of Western States Chiropractic College. She is also a #1 Best Selling author, international speaker, and host of The Dr Tyna Show Podcast. What we discuss: How to determine the right GLP-1 dosage for your body Why strength training is non-negotiable when taking these medications The surprising connections between hormones, pain management, and joint health How GLP-1s can help with addiction issues beyond just food cravings Thank you to our sponsor: Therasage: Head over to therasage.com and use code Be Bold for 15% off TruNiagen: Head over to truniagen.com and use code HUSTLE20 to get $20 off any purchase over $100. Magic Mind: Head over to www.magicmind.com/jen and use code Jen at checkout. Air Doctor: Go to airdoctorpro.com and use promo code HUSTLE for up to $300 off and a 3-year warranty on air purifiers. Bio.me: Link to daily prebiotic fiber here, code Jennifer20 for 20% off. Momentous: Shop this link and use code Jen for 20% off To learn more about Dr. Tyna Moore: Ozempic Uncovered: https://www.drtyna.com/ozempicuncovered Instagram: https://www.instagram.com/drtyna/ Youtube: https://youtube.com/@drtyna Find more from Jen: Website: https://www.jennifercohen.com/ Instagram: @therealjencohen Books: https://www.jennifercohen.com/books Speaking: https://www.jennifercohen.com/speaking-engagements
Chapter 1: Who are the hosts and guests in this episode?
Hi guys, it's Tony Robbins. You're listening to Habits and Hustle. Crush it.
Chapter 2: What are GLP-1 medications and why are they important?
Hey friends, you're listening to Fitness Friday on the Habits and Hustle podcast, where myself and my friends share quick and very actionable advice for you becoming your healthiest self. So stay tuned and let me know how you leveled up. Are there hidden benefits to GLP-1s that the FDA just isn't talking about?
In this Fitness Friday episode of Habits & Hustle, I sit down with Dr. Tina Moore to break down the truth about GLP-1 medications and the hype surrounding them. Dr. Tina is an expert in holistic regenerative medicine. She shares why these drugs are more than just weight loss tools and how the conversation around them has become very polarizing.
This is a short clip from our full interview where you can find the full episode linked in the show notes below. Please listen and comment with anything you'd like. Enjoy the episode. Yeah. I mean, the other thing is, like, how do you maximize the benefits, right?
Like, if you're just doing all the lifestyle things that we spoke about, like strength training, eating the amount of protein you should be eating daily, microdosing it or taking a dose that just kind of, like, helps you. Like, don't overdose.
Chapter 3: How can you maximize the benefits of GLP-1 medications?
Right. The appropriate dose for the patient.
What other ways are we able to maximize the benefits so we see the returns long-term?
Strength training. Build muscle. Focus on muscle. In fact, I just told my husband the other day, I'm like, you're just wasting all these peptides I'm spending money on because you're not in the gym. Exactly. Right. Really. Don't waste the opportunity. Strength train. Build the muscle. Eat the good food. Like I said, there is a potential. Well, not a potential. They have piles of studies on this.
Chapter 4: What role does strength training play when using GLP-1s?
There is a neuroplasticity that occurs on the GLP-1s, meaning your brain is wiring new pathways and learning new behaviors and hardwiring it in. So why not take that opportunity while you're having a little bit of appetite suppression? There's also this onus of responsibility. People get back in the driver's seat. A lot of people describe it as like, oh, I feel in control again.
And I'm not just in control of my eating. They're in control of their alcohol. They're in control of their smoking. They're in control of all these vices. Those are some other big industries that maybe turned off my Instagram.
Yeah, yeah, yeah, yeah. Honestly, it could be anybody at this point. It could be Anne over here who turned off your Instagram.
They're studying it for alcohol cessation, alcohol abuse syndrome.
It shuts off the noise in your brain. That's what I've heard.
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Chapter 5: Can GLP-1s help with addiction beyond food cravings?
The hedonic noise.
It shuts off the noise. So all these things that are your vices or your addictions, because food can be a massive addiction, right? Just how alcohol or drugs. And if it's shutting – it quiets your brain, actually, it can really save somebody's, like, mental health in that way itself.
Yes.
Right? My only thing I'm curious about is can your body become acclimated? And then, like – because I've also seen friends of mine – who it was great. And then after now six months of using it, they're eating again how they used to eat. Not because they're necessary. It's habitual. Because eventually you go back to your habits of what you used to do, right?
You can chew through it, as I call it. You can definitely override it.
Yeah.
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Chapter 6: What are the concerns about dosage and long-term use of GLP-1s?
Right. Right. Right. taken the peptide away, they're just going to crash and burn. And then they are going to have muscle loss. There is real muscle loss happening. I'm not saying it's not happening. And there is real side effects happening. I'm not negating that. I just think it's a dosing and management issue.
It's dosing and management. Yeah, I think so. Then let's talk about, you were saying... Middle age, right? Like you're saying, like, how can we use the GLP-1s to really maximize what's happening in perimetopause or even menopause for people who are going through that? I know we kind of mentioned with Dr. Mary that study.
Are there any other tips and tricks or things that we can do, in your opinion, to really kind of get us the biggest bang for our buck?
Well, I think HRT is critical and I've been using it in my patients for decades. And when that Women's Health Initiative study came out decades ago saying estrogen was dangerous, those of us who actually read the study, again, people aren't reading studies before they start vilifying everything. That study showed estrogen and progestins.
Progestins are fake progesterone and they will sit on the cell and they will not have the same impact as progesterone. And that's really dangerous. So we use progesterone, natural, real, bioidentical progesterone to offset any issues with estrogen. So I don't like using unmitigated estrogen alone. I like having a progesterone on board.
So anyway, those of us who read the study 20 years ago were like, we're going to keep using it. And we've been prescribing it ever since. And our patients are very happy on their hormone replacement therapy. I feel terrible because there's a whole generation of women who got severely screwed over. And this is why.
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Chapter 7: How do GLP-1s interact with hormones during menopause?
As we go into those years and our estrogen starts to wane, not even talking about progesterone, which is a neurohormone and we need it. But as our estrogen starts to wane, a couple of things happen that are really, really bad. Number one, we start to become more insulin resistant and we start to become more metabolically compromised, period. It's going to happen to all of us as our estrogen wanes.
Number two, our fat cells start to act differently. Our stem cells start preferentially turning into adipose tissue, which is fat tissue. And our fat tissue starts to redistribute itself into weird places. That's why we all turn into the sort of, they call it the gynoid shape, which is that belly with the skinny legs and arms.
Whereas we used to have, you know, the butts and hips, we start to get more of a male figure, which is that middle section, the middle age middle. and the skinnier arms and legs. And estrogen also helps with, to some degree, there's a mechanism where it helps with muscle protein synthesis. So we start to lose muscle, even with our best efforts.
Chapter 8: Why is hormone replacement therapy critical during perimenopause and menopause?
Our tendons and ligaments, that was my world, was regenerative orthopedics. Our tendons and ligaments start to become brittle and friable, and they They, I started getting, that's how I really knew I needed to double down on the estrogen. I just kept getting injured and injured and injured in all of my workouts. And I was like, what the hell is going on here? So this is a disaster.
And I've always told my patients, stay on this side of the curve, meaning start the hormones, test the hormones and start the hormones way before you think you need them. Because once you're on the other side of it, it's looking like from the studies that I've been reading, I've been really diving into the musculoskeletal component because, again, that's my world.
The pain component, there's a whole arsenal of impacts that estrogen has on our pain that they're just discovering and putting together, which is so cool. Because I've known this for decades with patients and I just didn't have the data to put my finger on it. I just had patient outcomes to prove it, you know? Yeah. Yeah.
Estrogen on the other side, especially after all the adipose tissue has laid itself down, because women will become, as I said, more insulin resistant, more metabolically compromised, and usually more obese. It just adds up, right? Like 60 some percent of postmenopausal women are obese.
So in this country, I don't know where that stat came from, but I heard somebody say it, who's an obesity doctor. And I looked it up and there is some version of that. I found like close percentages on either side, but it's a pretty significant number. Anyway, on the other side of that, estrogen, over here, estrogen's protective. It's got protective benefits to our cardiovascular system.
It's got protective benefits to our joints even. Over here, it might actually harm. Once people are over that hump, especially if they've laid down a lot of fat and they're metabolically pretty severely compromised. And I've seen this in patients. Estrogen just can go rogue. So it actually, over here, it causes vasodilation and it helps your vessels stay open and patent.
Over here, it can cause vasoconstriction.
Just by waiting too long to start taking it.
Dementia, over here, it's protective against dementia. Over here, it might actually cause dementia to get worse. Over here, it's protective to your knee joints. Over here, it might make your knees worse. So- This whole generation of women who got bamboozled by this stupid Women's Health Initiative study 20 years ago have completely been screwed over.
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