Huberman Lab

Essentials: How to Build Strength, Muscle Size & Endurance | Dr. Andy Galpin

02 Apr 2026

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In this Huberman Lab Essentials episode, my guest is Dr. Andy Galpin, PhD, Executive Director of the Human Performance Center at Parker University and an expert in building strength and muscle size (hypertrophy). We cover the core principles and protocols for building strength and muscle, including science-based guidance on reps, sets, frequency and rest intervals. We also discuss how breathing and mental focus can enhance training and how post-workout downregulation can speed recovery. Read the show notes at hubermanlab.com. Subscribe to Perform with Dr. Andy Galpin at performpodcast.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/huberman Eight Sleep: https://eightsleep.com/huberman Timestamps (00:00:00) Andy Galpin (00:00:39) 9 Exercise Adaptations; Progressive Overload (00:03:53) Progressive Overload, One-Rep Max, Soreness, Tool: Modifiable Variables (00:08:39) Sponsor: LMNT (00:10:12) Full-Body Workout, Exercise Selection (00:12:44) Training Intensity, Repetitions, Sets, Rest Intervals, Supersets (00:16:24) Sponsor: AG1 (00:17:48) Hypertrophy vs Strength Training Recovery (00:20:03) Training Volume & Frequency for Hypertrophy (00:21:56) Hypertrophy Rep Ranges, Frequency & Recovery; Cell Mechanisms (00:25:28) Sponsor: Eight Sleep (00:26:46) Tool: 3 x 5 Protocol; Power vs Strength (00:28:23) Mental Awareness in Training; Mind-Muscle Connection (00:31:25) Activating Muscle Groups, Awareness, Tool: Eccentric Overload (00:33:40) Perform Podcast: Season 3 (00:34:04) Tool: Resistance Training Breathing & Post-Training (00:38:20) Acknowledgments Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

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Huberman Lab

Essentials: How to Build Strength, Muscle Size & Endurance | Dr. Andy Galpin

This episode hasn't been transcribed yet

Other episodes from Huberman Lab

Essentials: The Neuroscience of Speech, Language & Music | Dr. Erich Jarvis

How Women Can Improve Their Fertility & Hormone Health | Dr. Natalie Crawford

Essentials: The Biology of Aggression, Mating & Arousal | Dr. David Anderson

How Hormones Shape Sexual Orientation & Behavior | Dr. Marc Breedlove

Essentials: Using Salt to Optimize Mental & Physical Performance

Essentials: Tools for Setting & Achieving Goals | Dr. Emily Balcetis

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