Journal of Clinical Oncology (JCO) Podcast

Lack of Gender Equity in Oncology Clinical Trial Advisory Board Membership

03 Nov 2022

Contributed by Lukas

Shannon Westin, Pamela Kunz, and Rachna Shroff discuss the lack of gender equity on oncology industry advisory boards. TRANSCRIPT  The guest on this ...

Universal Germline Genetic Testing in GI Malignancies

01 Nov 2022

Contributed by Lukas

Dr. Shannon Westin discusses germline genetic testing in gastrointestinal cancer with Heather Hampel and Dr. Matthew B. Yurgelun.   TRANSCRIPT The gu...

Light From Darkness - Navigating Postmortem Tissue Donation

20 Sep 2022

Contributed by Lukas

On this episode, our guests discuss how postmortem tissue donation can provide meaning to patients and their loved ones.   TRANSCRIPT Dr. Shannon Wes...

Physical Activity Improves Survival in Colorectal Cancer

12 Sep 2022

Contributed by Lukas

Dr. Westin and Dr. Justin C. Brown discuss how physical activity can improve disease-free and overall survival in colorectal cancer and its potential ...

Food Insecurity Interventions for Cancer Survivors With Dr. Francesca Gany and Dr. Theresa Hastert

29 Aug 2022

Contributed by Lukas

Shannon Westin, Francesca Gany, and Theresa Hastert discuss the topic of food insecurity among patients with cancer. TRANSCRIPT Dr. Shannon Westin: Th...

How to Confront Climate Change: A Framework for Change in the Operating Room and Hospital as a Whole. A Conversation with Dr. Anaeze Offodile and Dr. Elizabeth Yates

17 Jun 2022

Contributed by Lukas

Dr. Shannon Westin discusses the topic of climate change in the operating room with Dr. Anaeze Offodile and Dr. Elizabeth Yates.   TRANSCRIPT   The ...

JCO After Hours: A Discussion With Veena Shankaran and Scott Ramsey

01 Apr 2022

Contributed by Lukas

Shannon Westin, Veena Shankaran, and Scott Ramsey discuss the issue of financial toxicity among low- and middle-income cancer patients.   TRANSCRIPT ...

JCO After Hours: A Discussion With Virginia Sun

21 Feb 2022

Contributed by Lukas

Shannon Westin and Virginia Sun discuss the JCO article "Patient-Reported Outcome-Based Symptom Management Versus Usual Care After Lung Cancer Surgery...

JCO After Hours: A Discussion With Antonio Di Meglio

01 Feb 2022

Contributed by Lukas

Dr. Shannon Westin and Dr. Antonio Di Meglio discuss the issue of fatigue among cancer survivors.   Transcript [MUSIC PLAYING] Speaker 1: The guest o...

JCO After Hours: A Discussion With Abby Rosenberg and Reshma Jagsi

10 Jan 2022

Contributed by Lukas

Dr. Shannon Westin, Dr. Abby Rosenberg, and Dr. Reshma Jagsi discuss the timely issue of diversity, equity, and inclusion in the field of oncology.  ...

JCO After Hours: A Discussion With Michael Gnant and Kathy Miller

07 Dec 2021

Contributed by Lukas

Dr. Shannon Westin, Dr. Michael Gnant, and Dr. Kathy Miller discuss the results of the PALLAS trial.

JCO After Hours: A Discussion With Kirsten Beyer and Jennifer Griggs

19 Nov 2021

Contributed by Lukas

Dr. Shannon Westin, Dr. Kirsten Beyer and Dr. Jennifer Griggs discuss how mortgage lending bias and residential segregation intersect with cancer disp...

Is Dose-Adjusted EPOCH-R the Optimal Treatment for Children with Primary Mediastinal B-Cell Lymphoma?

20 Oct 2021

Contributed by Lukas

This podcast will discuss data from a phase II trial evaluating the dose-adjusted EOPCH-R chemo-immunotherapy regimen for the treatment of primary med...

Steroid Dose and Taxanes

10 Oct 2021

Contributed by Lukas

This podcast discusses the study, steroid dose reduction, practice experience, and guidance changes.   TRANSCRIPT [MUSIC PLAYING] ROBIN ZON: This JCO...

Commentary on GROINSS VII

01 Sep 2021

Contributed by Lukas

Improving care in vulvar cancer via the prospective Vulvar GROINSS VII study   TRANSCRIPT This JCO Podcast provides observations and commentary on th...

Harnessing the Power of Registries to Understand the Impact of Treatment for Hodgkin Lymphoma on Fertility

10 Aug 2021

Contributed by Lukas

Dr. Lindsay Morton of the National Cancer Institute at the National Institutes of Health reflects on research findings by Øvlisen et al that leverage...

Subspecialty Palliative Care Involvement May Lessen the Need for High-Intensity End-of-Life Care for Adolescents and Young Adults With Cancer

01 Aug 2021

Contributed by Lukas

This podcast describes the findings from a population-based retrospective decedent cohort study which suggest that palliative care involvement may be ...

Can the Incorporation of Minimal Residual Disease Detection Enhance Post-CAR T Outcomes in Patients With Large B-Cell Lymphoma?

10 Jul 2021

Contributed by Lukas

Minimal residual disease positivity is predictive of disease progression in patients with large B-cell lymphoma treated with anti-CD19 CAR T-cells.  ...

Moving Forward With Venetoclax-Based Combinations in Younger Adults With Acute Myeloid Leukemia

20 Jun 2021

Contributed by Lukas

Venetoclax in combination with FLAG-IDA chemotherapy shows safety and promising efficacy in both untreated and relapsed/refractory AML in this phase 1...

A Deep Dive Into HLA Typing For Unrelated Donor Hematopoietic Cell Transplantation

20 May 2021

Contributed by Lukas

This podcast comments on a large registry study evaluating the effect of ultra-high-resolution HLA typing on outcomes of unrelated donor transplantati...

PENELOPE-B: Exploration of CDK4/6 Inhibition in the Adjuvant Setting

10 May 2021

Contributed by Lukas

The PENELOPE-B phase III trial did not show a benefit to the addition of one year of the CDK4/6 inhibitor palbociclib to adjuvant endocrine therapy in...

ctDNA in DLBCL: A Blueprint for Better Clinical Trials?

10 Apr 2021

Contributed by Lukas

Current clinical characteristics and demographics are not sufficient to capture aggressive disease in clinical trials of newly diagnosed DLBCL. Novel ...

How Can We Expand Eligibility Criteria for Diffuse Large B-Cell Lymphoma Clinical Trials to Serve More Patients?

10 Mar 2021

Contributed by Lukas

This podcast considers the impact of exclusion criteria on clinical trials, generalizability, and the complexity of modernizing eligibility while main...

The Pathologist, the Surgeon, and the Rare Phyllodes Tumor

20 Dec 2020

Contributed by Lukas

This multi-institutional study highlights the heterogeneity of Phyllodes tumors of the breast and the importance of accurate pathology assessment and ...

Cancer Surgery in COVID-19-Free Facilities

29 Sep 2020

Contributed by Lukas

In this study of cancer operations conducted during the COVID-19 pandemic, rates of pulmonary complications and SARS-COV-2 nosocomial infections were ...

Finding a Needle in a Haystack of Mutations: Using Whole Genome Sequencing to Identify Patients with Low-Risk Myeloma

20 Jul 2020

Contributed by Lukas

This podcast reviews the results of the whole genome sequencing study by Samur and colleagues that identified a genomic signature associated with supe...

Advancing Knowledge on the Use of Dexrazoxane in Children With Acute Myeloid Leukemia and Other Childhood Cancers

11 Jun 2020

Contributed by Lukas

This podcast describes a study addressing the use of dexrazoxane as a cardioprotectant in a cohort of more than 1,000 pediatric acute myeloid leukemia...

Better Diet – Fewer Side Effects?

30 Apr 2020

Contributed by Lukas

This podcast reviews the results of the observational study by Ladas and colleagues that found protective associations between dietary antioxidant int...

Genetic Testing in Breast Cancer Patients: Striking the Balance Between Over Versus Undertesting

11 Mar 2020

Contributed by Lukas

This podcast summarizes and provides commentary on the recent article by Yadav et al. in which the authors demonstrate that expansion of the current N...

High Reward, High Toxicity: Combination Pembrolizumab and Lenvatinib in Advanced Endometrial Cancer

01 Mar 2020

Contributed by Lukas

The combination of pembrolizumab and lenvatinib is a promising second line option for metastatic or recurrent MSS endometrial cancer, although there c...

Optimizing Treatment Strategies for Germline BRCA/PALB2 Mutant Pancreatic Adenocarcinoma

21 Jan 2020

Contributed by Lukas

This podcast will discuss the findings from a phase II trial of gemcitabine, cisplatin and PARP inhibitor therapy in germline BRCA/PALB2 mutant pancre...

Immune Checkpoint Inhibitor Use in Patients With Inflammatory Bowel Disease: A Closer Look

08 Jan 2020

Contributed by Lukas

Towards improved characterization of immune-related adverse events in the setting of pre-existing autoimmune disease. TRANSCRIPT This JCO Podcast prov...

The High Prevalence of Exercise Intolerance in Adult Survivors of Childhood Cancer Is Predictive of All-Cause Mortality

08 Jan 2020

Contributed by Lukas

This podcast describes a study examining aerobic capacity in a cohort of over 1200 adult survivors of childhood cancer and related impairments of card...

Leptomeningeal Disease in EGFR-Mutated Lung Cancer: Can We Finally Define a Standard Treatment?

08 Jan 2020

Contributed by Lukas

This podcast describes the results of the BLOOM study, evaluating the efficacy of osimertinib in EGFR-mutated lung cancer with leptomeningeal disease ...

Advancing Treatment Options for Mismatch Repair-Deficient Metastatic Colorectal Cancers

08 Jan 2020

Contributed by Lukas

This podcast reviews the results of KEYNOTE 164 investigating the use of pembrolizumab for mismatch repair deficient metastatic colorectal cancer, the...

Keeping Mycosis Fungoides in Check: A Study of Pembrolizumab for Relapsed/Refractory MF and Sezary Syndrome

06 Jan 2020

Contributed by Lukas

This podcast evaluates results from a phase II clinical trial of pembrolizumab for relapsed Mycosis Fungoides and Sezary Syndrome in the context of th...

What's in a Name? An Introductory Guide

26 Dec 2019

Contributed by Lukas

This podcast discusses the results and implications of a recent study on gender bias in speaker introductions at an international oncology conference....

Resuming Life After Cancer Therapy: Treatment-Free Survival

10 Dec 2019

Contributed by Lukas

Treatment-free survival is a novel endpoint in immunotherapy. TRANSCRIPT This JCO Podcast provides observations and commentary on the JCO article "Tre...

Intratumoral Immune Infiltration in Follicular Lymphoma: Novel Insights into Early Relapse and Survival

01 Dec 2019

Contributed by Lukas

TRANSCRIPT This JCO Podcast provides observations and commentary on the JCO article "Progression of Disease Within 24 Months (POD24) in Follicular Lym...

MYC Rearrangements in Diffuse Large B-Cell Lymphoma: Impact and Implications for Diagnostic Testing

20 Nov 2019

Contributed by Lukas

This podcast summarizes the findings of the Lunenburg Lymphoma Biomarker Consortium systematic evaluation of MYC rearrangements in DLBCL, and discusse...

Centralization of High-Risk Surgery: Real Benefits for Patients From Health Systems

10 Nov 2019

Contributed by Lukas

This podcast discusses the work of Sheetz and colleagues describing the impact of centralization of high-risk cancer surgery within health care system...

Microsatellite Instability as a Prognostic Marker for Resectable Gastric Cancer and a Potential Biomarker for Perioperative Chemotherapy Benefit

01 Nov 2019

Contributed by Lukas

Dr. Osama Rahma, an Assistant Professor of Medicine at Harvard Medical School, Dana-Farber Cancer Institute, discusses the role of MSI in gastric ca...

Radiotherapy Dose Reduction Is Possible With Induction Chemotherapy for Pediatric Nasopharynx Cancer

01 Oct 2019

Contributed by Lukas

This JCO Podcast provides observations and commentary on the JCO article, "Treatment of Childhood Nasopharyngeal Carcinoma with Induction Chemotherapy...

Fine Tuning Therapy for Intermediate-Risk Neuroblastoma Using Clinical Response and Tumor Biology

09 Sep 2019

Contributed by Lukas

This JCO Podcast provides observations and commentary on the JCO article "Maintaining Outstanding Outcomes Using Response and Biology-Based Therapy fo...

Déjà Vu or Predicted: The Failure of Dose Adjusted EPOCH-R to Improve Outcomes in Diffuse Aggressive Lymphomas

03 Jul 2019

Contributed by Lukas

This JCO Podcast provides observations and commentary on the JCO article "Dose-Adjusted EPOCH-R Compared to R-CHOP as Frontline Therapy for Diffuse La...

Tackling Stage III EGFR Mutation-Positive Lung Cancer: Do We Really Know How?

02 Jul 2019

Contributed by Lukas

This JCO Podcast provides observations and commentary on the JCO article "Erlotinib Versus Gemcitabine Plus Cisplatin as Neoadjuvant Treatment for Sta...

The Need for Continued Vigilance in Patients with Diffuse Large B-Cell Lymphoma

06 Jun 2019

Contributed by Lukas

This JCO Podcast provides observations and commentary on the JCO article 'Late Relapses in Patients With Diffuse Large B-Cell Lymphoma Treated With Im...

A Second Chance at Checkpoint Inhibition After Initial Immune-Mediated Diarrhea and Colitis

06 Jun 2019

Contributed by Lukas

This JCO Podcast provides observations and commentary on the JCO article "Resumption of Immune Checkpoint Inhibitor Therapy After Immune-Mediated ...

Anticipating the Future of Hodgkin Lymphoma

21 May 2019

Contributed by Lukas

This JCO Podcast provides observations and commentary on the JCO article "PET Score Has Greater Prognostic Significance Than Pre-Treatment Risk Strati...

An Advance for the Treatment of Osteosarcoma

23 Apr 2019

Contributed by Lukas

This podcast provides observations and commentary on the JCO article "Randomized, Double-Blind, Phase II Study of Regorafenib in Patients with Metasta...

The Heartbreak of Cancer Treatment: The Latest in Late Cardiac Toxicity

13 Mar 2019

Contributed by Lukas

This JCO Podcast provides observations and commentary on the JCO article "Therapy-Related Cardiac Risk in Childhood Cancer Survivors: An Analysis of t...

Programmed Cell Death-1 Pathway Inhibitors Enter Center Stage as First-Line Treatment of Advanced Merkel Cell Carcinoma

08 Mar 2019

Contributed by Lukas

This JCO Podcast provides observations and commentary on the JCO article Durable Tumor Regression and Overall Survival in Patients with Advanced Merke...

Potential for Parenthood After Childhood Cancer: Perceptions and Reality

27 Feb 2019

Contributed by Lukas

This JCO Podcast provides observations and commentary on the JCO article Gonadal Functioning and Perceptions of Infertility Risk among Adult Survivors...

How Should We Interpret Indeterminate Pulmonary Nodules at Diagnosis in Children With Rhabdomyosarcoma?

08 Feb 2019

Contributed by Lukas

This JCO podcast provides observations and commentaries on the JCO article entitled "Indeterminate Pulmonary Nodules at diagnosis in Rhabdomyosarcoma:...

The End of ENDoxifen Metabolite and CYP2D6 Testing in Tamoxifen-Treated Women?

24 Jan 2019

Contributed by Lukas

This JCO Podcast provides observations and commentary on the JCO article "Tamoxifen pharmacogenetics and metabolism: Results from the prospective CYPT...

Less is More: Precision Surveillance Imaging for Wilms Tumor

18 Oct 2018

Contributed by Lukas

This JCO Podcast provides observations and commentary on the JCO article "Impact of Surveillance Imaging Modality on Survival After Recurrence in Pati...

How Low Can You Go? Impact of Baseline Corticosteroid Use on Immunotherapy Outcomes in Patients With Advanced Non-Small-Cell Lung Cancer

20 Aug 2018

Contributed by Lukas

This JCO Podcast provides observations and commentary on the JCO article, "Impact of Baseline Steroids on Efficacy of PD-(L)1 Blockade in Patients Wit...

Expanding Treatment Options for Hormone Receptor-Positive, HER2-Positive Metastatic Breast Cancer

14 Aug 2018

Contributed by Lukas

Read the related article "First-Line Trastuzumab Plus an Aromatase Inhibitor, With or Without Pertuzumab, in Human Epidermal Growth Factor Receptor 2–...

The Addition of Another Camptothecin Fails to Improve Outcomes in Patients With Intermediate-Risk Rhabdomyosarcoma

09 Aug 2018

Contributed by Lukas

Read the related article "Addition of Vincristine and Irinotecan to Vincristine, Dactinomycin, and Cyclophosphamide Does Not Improve Outcome for Inter...

The Addition of IKZF1 Deletion in Risk Stratification for Children with Newly Diagnosed B-Acute Lymphoblastic Leukemia Leads to Improved Survival: Results of the Malaysia-Singapore ALL 2010 Study

26 Jul 2018

Contributed by Lukas

Intensifying therapy in children with pediatric B-ALL and IKZF1 deletions leads to improved survival. Read the related article "Intensifying Treatment...

Psychosocial Outcomes Following Contralateral Prophylactic Mastectomy: Insights and Opportunities

25 Jul 2018

Contributed by Lukas

Discussion of a recent study that evaluated prospectively psychosocial well being measures in breast cancer patients before and after receipt of CPM. ...

Risky Business: PD-1 Immune Checkpoint Blockade in Thymic Epithelial Neoplasms

18 Jun 2018

Contributed by Lukas

This podcast discusses the important risks and potential benefits of PD-1 immune checkpoint blockade in patients with thymic epithelial neoplasms. Rea...

Don't Treat Me Like a Child: The Intensification of Conventional Chemotherapy in Adults With Acute Lymphoblastic Leukemia

04 Jun 2018

Contributed by Lukas

GRAALL-2005 study shows no overall benefit for cyclophosphamide intensification in older adults with ALL, despite a general improvement in outcomes fo...

Multiple Myeloma Joins the Car T Race

29 May 2018

Contributed by Lukas

Highlighting the importance of BCMA-CAR T therapy for patients with relapsed refractory multiple myeloma and discusses future avenues of clinical inve...

Cardiotoxicity After Breast Cancer Radiotherapy: Which Part of the Heart Matters Most?

23 May 2018

Contributed by Lukas

This podcast includes commentary upon a large case control series that examined the incidence of cardiac injury in association with radiation dose to ...

Should Prophylactic Cranial Irradiation Be Used in Patients with Stage III Non-Small Cell Lung Cancer?

22 May 2018

Contributed by Lukas

This is an evaluation of PCI in stage III Non-Small-Cell Lung Cancer.  While the incidence of symptomatic brain metastases is reduced, neurological t...

The Medical Marijuana Conundrum: When Public Interest Outpaces Medical Knowledge

11 May 2018

Contributed by Lukas

The public perception of medical marijuana has outpaced medical knowledge. Oncologists encounter an increasing number of patient questions and interes...

Racial Disparities in Medical Financial Hardship Among Cancer Survivors

18 Apr 2018

Contributed by Lukas

This commentary summarizes findings from a study of racial disparities in medical financial hardship, identifies gaps in the current evidence base, an...

Late Infectious Death: Asplenic Adult Survivors of Child Cancer

17 Apr 2018

Contributed by Lukas

This  podcast discusses a CCSS study of very late infection-related mortality in asplenic adult survivors childhood cancer, with risk increasing prec...

Extending the Reach of Targeted Therapy for Hormone Receptor-Positive Advanced Breast Cancer

17 Apr 2018

Contributed by Lukas

This podcast discusses a phase II trial evaluating the combination of everolimus and fulvestrant compared to fulvestrant alone in pretreated hormone r...

An International Phase II Trial of Single-Agent Nivolumab for Hodgkin Lymphoma Relapsed or Refractory After Autologous Stem Cell Transplant

27 Mar 2018

Contributed by Lukas

This podcast describes the extended follow-up of the large International phase II CheckMate 205 study of single-agent nivolumab for patients with rela...

Exploring a New Delivery Model for Germline Genetic Testing for Patients With Ovarian Cancer

20 Mar 2018

Contributed by Lukas

This podcast provides comment on the accompanying JCO article "ENGAGE: Evaluation of a streamlined oncologist-led BRCA mutation testing and counseling...

Is Earlier Treatment Better For Patients? The Case of Docetaxel in Metastatic Castration-Sensitive Prostate Cancer

09 Mar 2018

Contributed by Lukas

This commentary examines whether patient-reported outcomes were substantially different in men given chemohormonal therapy versus hormone therapy in t...

The Decision to Image Breast Cancer Patients with Local-Regional Recurrence

31 Jan 2018

Contributed by Lukas

This podcast reflects upon a recent retrospective study of breast cancer patients with local regional recurrence, and whether imaging is needed for al...

The Importance of Reading Clinical Trial Protocols Simultaneously With Published Studies

24 Jan 2018

Contributed by Lukas

This podcast discusses whether the primary outcomes and study design for the reported trial were properly pre-specified and pre-registered prior to ac...

Understanding the 'Value-Added' by Specialized Pediatric Palliative Care Teams in the Care of Children With Cancer at the End of Life

22 Jan 2018

Contributed by Lukas

This podcast reviews the aims, methodology, and results of a population-level study that investigates the value of specialized pediatric palliative ca...

Survival Following Radiofrequency Ablation Versus Stereotactic Body Radiotherapy for Early-Stage Hepatocellular Carcinoma

12 Jan 2018

Contributed by Lukas

This podcast reviews the current evidence for using radiofrequency ablation or stereotactic body radiotherapy as primary treatment for nonsurgical man...

The True Costs of the 21-Gene Assay in a Cohort of 1,000 Patients

01 Dec 2017

Contributed by Lukas

This podcast addresses the clinical implications of the high cost of the 21-gene assay in women with ER-positive, node-negative breast cancer. Related...

Persistent Use of Opioids After Cancer Surgery

19 Oct 2017

Contributed by Lukas

Though opioid abuse is clearly an issue for cancer patients post-surgery, many other potential factors were not accounted for and should be included i...

Discussion on the Cost–Effectiveness Analysis of the CALGB/Alliance Trial and the Use of Zoledronic Acid Generic in Women With Metastatic Breast Cancer

12 Oct 2017

Contributed by Lukas

The paper examines the cost-effectiveness of schedules of bone-modifying agents in patients with breast cancer and skeletal metastases and supports th...

Can We Simplify the Treatment of Myelofibrosis?

21 Sep 2017

Contributed by Lukas

In this randomized trial, momelotinib was non-inferior to ruxolitinib for spleen response but was less effective in controlling symptoms. Related Arti...

Lessons to be Learned about the Significance of Educational Level in Adults with Acute Myeloid Leukemia

11 Sep 2017

Contributed by Lukas

A Danish population based study of adults with acute myeloid leukemia is described, and the potential significance of educational level as a predictor...

More Often but Not Early: Hospice Use Among Older Adults With AML

17 Aug 2017

Contributed by Lukas

With a large database analysis, the authors found an increase in hospice use among older patients with AML at the end of life, but this increase was l...

T-cell Therapy for Viral Infections after Stem Cell Transplant

17 Aug 2017

Contributed by Lukas

T-cell therapies targeting viral diseases have evolved from a patient-specific therapy, targeting a single virus, and requiring multiple months of spe...

Shared Risk Factors in Cancer and Cardiovascular Disease: Can We Make a Difference?

12 Jul 2017

Contributed by Lukas

This podcast examines the growing evidence to support the link between risk factors for cardiovascular disease and cancer. Related Article: Guideline-...

Should Metabolic Imaging to Assess Minimal Residual Disease (MRD) Become a Clinical Endpoint in Multiple Myeloma?

07 Jul 2017

Contributed by Lukas

Normalization of PET-CT is a strong predictor   for progression free survival (PFS) and overall survival (OS) in multiple myeloma (MM) Related Artic...

Considerations in Predicting Neuropsychological Outcomes in Children Treated for ALL

03 Jul 2017

Contributed by Lukas

Randomization to different methotrexate and steroid treatment strategies was not related to neuropsychological outcome in children treated for B-ALL, ...

Low-Income Subsidy and Financial Barrier to Access Costly Oral Chemotherapy Drugs for Myeloma Patients Enrolled in Medicare Part D

08 Jun 2017

Contributed by Lukas

This podcast summarizes the study finding and discuss the clinical and policy implication of an article to appear in JCO that examined the impact of ...

Beyond the Beam: Thinking about Subsequent Malignancy Risk Outside of the Radiation Paradigm,"

22 May 2017

Contributed by Lukas

In a unique approach to subsequent malignancy research, Teepen and colleagues report on subsequent solid cancer risk associated with chemotherapy expo...

Discussion of the SWORD-Study and Fear of Cancer Recurrence Intervention Research Randomized Controlled Trial

12 May 2017

Contributed by Lukas

The SWORD study is one of the first randomized controlled trials targeting fear of cancer recurrence (FCR) and results support the efficacy of cogniti...

Optimizing Up-Front Therapy for Double-Hit Lymphoma

05 May 2017

Contributed by Lukas

This podcast discusses the role of consolidation stem cell transplantation in patients with double-hit lymphoma who achieve a complete response to fro...

Chronic Conditions in Cancer Survivors

04 May 2017

Contributed by Lukas

This podcast summarizes and discusses the findings from a study by Guy and colleagues about the economic impact of chronic conditions in cancer surviv...

Do Treatment Summary Survivorship Plans Make Any Difference?

18 Apr 2017

Contributed by Lukas

This randomized controlled trial shows that Treatment Summary Survivorship Plans increase physician recommendation of needed care among breast cancer ...

The Impact of Cigarette Smoking on Survival in Patients with Pancreatic Cancer

30 Mar 2017

Contributed by Lukas

This podcast discusses the association between smoking and risk of death from pancreatic cancer.

Better Patient-Reported Outcomes After Autologous Breast Reconstruction Compared to Implant-Based Reconstruction Study

28 Mar 2017

Contributed by Lukas

Patients who had autologous reconstruction had higher satisfaction with breasts and well-being than patients who had implant-based reconstruction, but...

Drugs Don't Work in Patients Who Don't Take Them

24 Mar 2017

Contributed by Lukas

This podcast describes the results and implications of the article published by Landier et al, describing the relationship between 6-MP ingestion habi...

Pembrolizumab is Safe and Active in Platinum- and Cetuximab-Refractory Head and Neck Squamous Cell Carcinoma

22 Mar 2017

Contributed by Lukas

By Amanda Psyrri  The findings of KEYNOTE-055 are summarized and compared to other immunotherapy studies in recurrent/metastatic head and neck squam...

Long-Term Follow-up of AF-001JP: A Phase I/II Study of Alectinib in ALK-Positive NSCLC

15 Mar 2017

Contributed by Lukas

Podcast re: 'Three-year Follow-up of an Alectinib Phase 1/2 Study in ALK-Positive Non-Small-Cell Lung Cancer: AF-001JP' by Tamura et al.

Late Relapse in Hodgkin Lymphoma Persisting Even at 20 Years: Implications for Therapeutic Intensity and Disease Biology

28 Feb 2017

Contributed by Lukas

This podcast discusses the JCO article, "Late Relapse of classical Hodgkin Lymphoma: An Analysis of the German Hodgkin Study Group HD7-HD12 Trials" by...

Intensification of Consolidation Therapy for Acute Myeloid Leukemia by the Addition of Clofarabine to Cytarabine Improves Relapse-Free Survival

21 Feb 2017

Contributed by Lukas

By Kenneth Bradstock This podcast describes a clinical trial of clofarabine in consolidation therapy for adults with acute myeloid leukemia. Related a...