Vasek Mlejnsky from E2B joins us today to talk about sandboxes for AI agents. In the last 2 years, E2B has grown from a handful of developers building on it to being used by ~50% of the Fortune 500 and generating millions of sandboxes each week for their customers. As the “death of chat completions” approaches, LLMs workflows and agents are relying more and more on tool usage and multi-modality. The most common use cases for their sandboxes: - Run data analysis and charting (like Perplexity) - Execute arbitrary code generated by the model (like Manus does) - Running evals on code generation (see LMArena Web) - Doing reinforcement learning for code capabilities (like HuggingFace) Timestamps: 00:00:00 Introductions 00:00:37 Origin of DevBook - E2B 00:02:35 Early Experiments with GPT-3.5 and Building AI Agents 00:05:19 Building an Agent Cloud 00:07:27 Challenges of Building with Early LLMs 00:10:35 E2B Use Cases 00:13:52 E2B Growth vs Models Capabilities 00:15:03 The LLM Operating System (LLMOS) Landscape 00:20:12 Breakdown of JavaScript vs Python Usage on E2B 00:21:50 AI VMs vs Traditional Cloud 00:26:28 Technical Specifications of E2B Sandboxes 00:29:43 Usage-based billing infrastructure 00:34:08 Pricing AI on Value Delivered vs Token Usage 00:36:24 Forking, Checkpoints, and Parallel Execution in Sandboxes 00:39:18 Future Plans for Toolkit and Higher-Level Agent Frameworks 00:42:35 Limitations of Chat-Based Interfaces and the Future of Agents 00:44:00 MCPs and Remote Agent Capabilities 00:49:22 LLMs.txt, scrapers, and bad AI bots 00:53:00 Manus and Computer Use on E2B 00:55:03 E2B for RL with Hugging Face 00:56:58 E2B for Agent Evaluation on LMArena 00:58:12 Long-Term Vision: E2B as Full Lifecycle Infrastructure for LLMs 01:00:45 Future Plans for Hosting and Deployment of LLM-Generated Apps 01:01:15 Why E2B Moved to San Francisco 01:05:49 Open Roles and Hiring Plans at E2B

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