Menu
Sign In Search Podcasts Charts People & Topics Add Podcast API Blog Pricing
Podcast Image

Motley Fool Money

Can AI Drive Peloton’s Comeback?

12 Nov 2025

Transcription

Full Episode

5.279 - 37.927 Travis Hoium

Is Peloton making a comeback? Motley Fool Money starts now. Welcome to Motley Fool Money. I'm Travis Hoyum, joined today by Rachel Warren and John Quast. I do want to get to Peloton because they have a really fascinating story over the last few years. But we're going to start with one of the big deals of the week. That is Pfizer winning a bid against Novo Nordisk for Metzera.

0

38.849 - 60.784 Travis Hoium

Rachel, I got through all of that word salad, so I'm I'm proud of myself there. This is an obesity treatment startup, so they don't actually have a product out there. But there was a bidding war for these companies. What do we need to know about Pfizer actually? It seems like getting into the weight loss game that they have not had a lot of success, like companies like Eli Lilly and Novo Norris.

0

60.983 - 84.2 Rachel Warren

This is an area that Pfizer has wanted to expand into for a while now. You might remember at one point, they actually had their own GLP-1 candidate. They had to discontinue that back in April of this year. There had been a bidding war that essentially erupted between Pfizer and Novonordisk for Metzera. That started back after Pfizer's initial offer in September. Pfizer ultimately won the bid.

0

84.26 - 98.347 Rachel Warren

They had a sweetened offer of up to $10 billion. And this acquisition could really position Pfizer in the long run in the highly competitive and obviously growing obesity treatment market where they've previously struggled with their own development.

0

98.647 - 118.315 Rachel Warren

So, Metzera has a pipeline of drug candidates for metabolic diseases that target different gut hormones that offer some really key advantages in efficacy and tolerance. Really a key feature of the drugs that Mitzera is developing is the potential for once-monthly dosing. That would be a significant improvement over the weekly injections of current treatments.

119.236 - 137.532 Rachel Warren

So their lead candidates, one's a monthly injectable GLP-1 receptor. They're also working on an oral version. They've also got a monthly amylin analog candidate. And Pfizer plans to use their own manufacturing and commercial infrastructure to help accelerate Mitzera's drugs, which is a really key advantage. So good things happening from this deal.

137.512 - 156.145 Travis Hoium

So for those of us who are not quite as familiar with the pharmaceutical space, is this sort of another entrant into the GLP-1? Because we've been hearing about GLP-1s for years. The prices are starting to come down. We've heard about there's some oral treatments that are coming to market, I believe, next year. There's a bunch of

156.125 - 179.542 Travis Hoium

stuff that's in clinical trial right now, is this another expansion of the market or is this going to be a game changer? Are these incremental improvements that are being made? Yes, a monthly injection is better than a weekly injection, but if it's $500 and the weekly is $200, that will maybe make the difference. Is that the way to think about it?

179.562 - 183.027 Travis Hoium

It's at least getting Pfizer into the game, but it does increase competition?

Comments

There are no comments yet.

Please log in to write the first comment.