This episode is a conversation with Drs. Clifford Jack and Kevin Duff about recent updates to the diagnosis and staging of Alzheimer's disease (AD). We discuss biological versus clinical/pathological approaches to diagnosing AD, analogies between AD and other medical conditions, the predictive validity of amyloid PET in asymptomatic older adults, the specific purpose of the recent Alzheimer's Association diagnosis and staging paper, the utility of currently available AD biomarkers, the status of blood-based biomarkers for AD, the amyloid hypothesis, concerns from neuropsychologists about the recent Alzheimer's Association biological definition of AD, and current state of the science for antiamyloid treatments in AD, among other topics. Show notes are available at www.NavNeuro.com/156 _________________ If you'd like to support the show, here are a few easy ways: 1) Get CE credits for listening to select episodes: www.NavNeuro.com/INS 2) Tell your friends and colleagues about it 3) Subscribe (free) and leave an Apple Podcasts rating/review: www.NavNeuro.com/itunes 4) Check out our book Becoming a Neuropsychologist, and leave it an Amazon rating Thanks for listening, and join us next time as we continue to navigate the brain and behavior! [Note: This podcast and all linked content is intended for general educational purposes only and does not constitute the practice of psychology or any other professional healthcare advice and services. No professional relationship is formed between hosts and listeners. All content is to be used at listeners' own risk. Users should always seek appropriate medical and psychological care from their licensed healthcare provider.]

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“What did the council decide on item 42?” — answered with the speaker and the moment.

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