NEJM This Week
Episodes
Introducing: Intention to Treat — Season 2
29 Apr 2026
Contributed by Lukas
What happens when medicine gets race wrong? In a new 8-week series, The Race Equation confronts harmful assumptions about race in clinical medicine, w...
NEJM This Week — April 30, 2026
29 Apr 2026
Contributed by Lukas
This week, we feature advances in targeted therapy for HER2-mutant lung cancer, interventions to reduce maternal infection, an emerging treatment for ...
NEJM This Week — April 23, 2026
22 Apr 2026
Contributed by Lukas
This week, we explore new strategies for blood-pressure control after intracerebral hemorrhage, Covid-19 treatment in higher-risk patients, hormonal t...
NEJM This Week — April 16, 2026
15 Apr 2026
Contributed by Lukas
This week, we present new research on stroke prevention, Kawasaki disease, ICU infection strategies, and immune thrombocytopenia. We review hormone th...
NEJM This Week — April 9, 2026
08 Apr 2026
Contributed by Lukas
This week, we present new research on intensive LDL cholesterol targets, team-based strategies to improve blood pressure control, emerging therapies f...
NEJM This Week — April 2, 2026
01 Apr 2026
Contributed by Lukas
This week, we present new research on treatment for muscle-invasive bladder cancer, left atrial appendage closure versus medical therapy for atrial fi...
NEJM This Week — March 26, 2026
25 Mar 2026
Contributed by Lukas
This week, we present new clinical trials on immunotherapy for stage III mismatch repair–deficient colon cancer, early surgery for asymptomatic aort...
NEJM This Week — March 12, 2026
11 Mar 2026
Contributed by Lukas
This week, we explore new evidence comparing oral anticoagulants for acute venous thromboembolism, treatment for chemotherapy-induced thrombocytopenia...
NEJM This Week — March 5, 2026
04 Mar 2026
Contributed by Lukas
This week, we explore a phase 3 trial of finerenone in type 1 diabetes and chronic kidney disease and guidance on timing of nonculprit-lesion PCI afte...
NEJM This Week — February 26, 2026
25 Feb 2026
Contributed by Lukas
This week, we explore a new standard of care for high-risk HER2-positive early breast cancer, long-acting therapy for people with HIV facing adherence...
NEJM This Week — February 19, 2026
18 Feb 2026
Contributed by Lukas
This week, we highlight major advances in multiple myeloma, gene therapy for cystinosis, and experimental treatments for myotonic dystrophy. We review...
NEJM This Week — February 12, 2026
11 Feb 2026
Contributed by Lukas
This week includes studies on promising new therapies for IgA nephropathy, evolving antithrombotic strategies after coronary stenting, and the incitin...
NEJM This Week — February 5, 2026
04 Feb 2026
Contributed by Lukas
This week, we look at new evidence on oral cholesterol-lowering therapy, the evolving role of beta-blockers after myocardial infarction, and advances ...
NEJM This Week — January 29, 2026
28 Jan 2026
Contributed by Lukas
This week, we explore new therapies to reduce pancreatitis risk in severe hypertriglyceridemia, advances in breast cancer treatment, and long-term res...
NEJM This Week — January 22, 2026
21 Jan 2026
Contributed by Lukas
In this episode, we explore evolving evidence on anticoagulation after atrial fibrillation ablation, long-term outcomes with immunotherapy for melanom...
NEJM This Week — January 15, 2026
14 Jan 2026
Contributed by Lukas
This week, we explore new evidence on managing asymptomatic carotid stenosis, restoring vision in advanced macular degeneration, and preventing migrai...
NEJM This Week — January 8, 2026
07 Jan 2026
Contributed by Lukas
This week, we explore new options in cardiovascular prevention, fish-oil supplementation in dialysis patients, RSV vaccination, and cutting-edge cellu...
NEJM This Week — January 1, 2026
31 Dec 2025
Contributed by Lukas
This week, we share advances in treatment for EGFR-mutated lung cancer, a brain-penetrant enzyme therapy for a rare pediatric disorder, and dual targe...
NEJM This Week — December 18, 2025
17 Dec 2025
Contributed by Lukas
This week, we look at ctDNA-guided immunotherapy for bladder cancer, cardiovascular outcomes with tirzepatide, and evidence that one HPV vaccine dose ...
NEJM This Week — December 11, 2025
10 Dec 2025
Contributed by Lukas
This week, we look at new studies on high-dose influenza vaccines for older adults, antiplatelet therapy after coronary surgery, and HER2-targeted imm...
NEJM This Week — December 4, 2025
03 Dec 2025
Contributed by Lukas
This week, we look at new trials on glucocorticoids for pneumonia in Africa, shunting for normal-pressure hydrocephalus, and pegcetacoplan for two rar...
NEJM This Week — November 27, 2025
26 Nov 2025
Contributed by Lukas
This week, we look at new studies on early aspirin discontinuation after myocardial infarction, an antiviral pill for dengue prevention, and CRISPR-ba...
NEJM This Week — November 20, 2025
19 Nov 2025
Contributed by Lukas
This week, we look at new research on potassium optimization in patients with defibrillators, reducing antihypertensive therapy in nursing homes, an m...
NEJM This Week — November 13, 2025
12 Nov 2025
Contributed by Lukas
In this episode, we look at new trials on deferring arterial catheterization in shock, beta-blocker use after myocardial infarction, and a treatment f...
NEJM This Week — November 6, 2025
05 Nov 2025
Contributed by Lukas
In this episode, we discuss long-term outcomes after chest-wall irradiation for breast cancer, new treatments for psoriasis and obesity, and early res...
NEJM This Week — October 30, 2025
29 Oct 2025
Contributed by Lukas
This week, we look at new findings from the European prostate cancer screening study, advances in lung cancer therapy, physical therapy for meniscal t...
NEJM This Week — October 23, 2025
22 Oct 2025
Contributed by Lukas
In this episode, we look at new research on mucoactive therapy for bronchiectasis, aspirin use in anticoagulated patients with coronary disease, and s...
NEJM This Week — October 16, 2025
15 Oct 2025
Contributed by Lukas
In this episode, we look at new research in cervical cancer, lupus, gene therapy for immune deficiency, and malaria prevention in infants. We review h...
NEJM This Week — October 9, 2025
08 Oct 2025
Contributed by Lukas
In this episode, we explore new treatments for hypertension, hereditary amyloidosis, and malaria prevention, along with insights on mosquito-borne dis...
NEJM This Week — October 2, 2025
01 Oct 2025
Contributed by Lukas
Featuring articles on severe acute malnutrition with gastroenteritis in children, medical imaging and pediatric cancer risk, moderate hypertriglycerid...
NEJM This Week — September 25, 2025
24 Sep 2025
Contributed by Lukas
Featuring articles on heart failure, provoked venous thromboembolism, chronic lymphocytic leukemia, and acute ischemic stroke; a review article on med...
NEJM This Week — September 18, 2025
17 Sep 2025
Contributed by Lukas
Featuring articles on PI3K-altered colorectal cancer, type 2 diabetes, oral semaglutide, and proportional-assist ventilation; a review article on tumo...
NEJM This Week — September 11, 2025
10 Sep 2025
Contributed by Lukas
Featuring articles on hypertrophic cardiomyopathy, rehabilitation after myocardial infarction in older adults, the 2024 Marburg virus disease outbreak...
NEJM This Week — September 4, 2025
03 Sep 2025
Contributed by Lukas
Featuring articles on obesity, type 1 diabetes, syphilis, and heparin-induced thrombocytopenia; a review article on the management of acute type B ao...
NEJM This Week — August 21, 2025
20 Aug 2025
Contributed by Lukas
Featuring articles on lung cancer, vasomotor symptoms in breast cancer, autoimmune pulmonary alveolar proteinosis, and high-risk cutaneous squamous-ce...
NEJM This Week — August 14, 2025
13 Aug 2025
Contributed by Lukas
Featuring articles on overweight, obesity and diabetes; lactated Ringer’s solution versus normal saline; and spinal muscular atrophy; a review artic...
NEJM This Week — August 7, 2025
06 Aug 2025
Contributed by Lukas
Featuring articles on treatments for chronic kidney disease and type 2 diabetes, bubonic plague, and advanced breast cancer; a review article on hypog...