Preliminary analysis shows the first effective coronavirus vaccine can prevent more than 90% of people from getting the virus. Fergus brings us his interview with the developers, Pfizer, and Professor of immunology, Peter Openshaw sets the news in context. And as hopes about the vaccine send global markets skyrocketing, Laura and BBC Business reporter Vishala Sri-Pathma help us understand who are the financial winners and losers. Studio Director: Emma Crowe Producers: Frankie Tobi and Jo Deahl Assistant Editor: Emma Close Editor: Dino Sofos

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“What did the council decide on item 42?” — answered with the speaker and the moment.