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Science Friday

Predicting Heart Disease From Chest X-Rays With AI | Storing New Memories During Sleep

08 Apr 2024

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Dr. Eric Topol discusses the promise of “opportunistic” AI, using medical scans for unintended diagnostic purposes. Also, a study in mice found that the brain tags new memories through a “sharp wave ripple” mechanism that then repeats during sleep.How AI Could Predict Heart Disease From Chest X-RaysResearch on medical uses for artificial intelligence in medicine is exploding, with scientists exploring methods like using the retina to predict disease onset. That’s one example of a growing body of research on “opportunistic” AI, the practice of analyzing medical scans in unconventional ways and for unintended diagnostic purposes.Now, there’s some evidence to suggest that AI can mine data from chest x-rays to assess the risk of cardiovascular disease and detect diabetes.Ira talks with Dr. Eric Topol, founder and director of the Scripps Research Translational Institute and professor of molecular medicine.Neurons ‘Tag’ New Memories For Storage During SleepAll day long we’re taking in information and forming memories. Some stick around, others quickly fade away. But how does your brain push those memories into long term storage? And how does our brain recognize which memories should be kept and which should be discarded?This topic has been debated for decades, and a recent study in mice may help scientists understand this process.Researchers found that during the day, as the mice formed memories, cells in the hippocampus fired in a formation called “sharp wave ripples.” These are markers that tell the brain to keep those memories for later. Then, while the mice slept, those same sharp wave ripples activated again, and locked in those memories.Ira talks with Dr. György Buzsáki, professor of neuroscience at the NYU Grossman School of Medicine, about the findings of the study, which was published in the journal Science.Transcripts for each segment will be available after the show airs on sciencefriday.com.  Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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