First Malaria Vaccine Is Approved by WHO The malaria parasite is one of the world’s deadliest infectious diseases, killing on average about 500,000 people per year—half of them children under the age of 5, nearly all of them in sub-Saharan Africa. Now, the World Health Organization has finally approved RTS,S or Mosquirix, the first vaccine against Plasmodium falciparum, which is the most deadly strain of the parasite. The vaccine has already been administered via a pilot program to 800,000 children in Kenya, Ghana, and Malawi, and in clinical trials showed an efficacy rate of about 50% against severe disease. WNYC’s Nsikan Akpan explains this and other stories, including a climate change-linked Nobel Prize in physics, controversy over the naming of the James Webb Space Telescope, and a new surveillance method that uses only the shadows you cast on a blank wall. Will Improved Testing And New Antivirals Change The Pandemic’s Path? Late last week, the pharmaceutical company Merck released data on a new antiviral medication called molnupiravir—a drug taken as a course of pills over five days that the company said was dramatically effective at keeping people with COVID-19 out of the hospital. In a press release, the company said that trial participants on the medication had a 50% lower risk of hospitalization or death compared to people getting the placebo. And while eight people in the placebo group died during the trial, none of the people getting the new drug did. However, the full data from the trial has yet to be released—and the medication must still go through the FDA approval process before it can be used. Matthew Herper, senior writer at STAT covering medicine, joins Ira to talk about the drug and what questions remain. Then, infectious disease specialist and epidemiologist Céline Gounder discusses other recent coronavirus news—from a government plan to spend a billion dollars on at-home testing to recent data on the Delta variant, including projections of what might happen next. Preparing For The Next Pandemic Needs To Start Now The United States has a long history of public health crises. For many, our first pandemic has been COVID-19. But long before the SARS-CoV-2 virus arrived, HIV, measles, and the flu all left a lasting impact. As a wealthy country, you may think the United States would be prepared to deal with public health crises, since they happen here with a degree of regularity. However, that’s not the case. The longstanding issues that left the country vulnerable to COVID-19 are explored in a recent article from The Atlantic, called “We’re Already Barreling Toward the Next Pandemic.” The piece was written by science writer Ed Yong, who won a Pulitzer Prize last year for his coverage of COVID-19. Ira speaks to Ed and Gregg Gonsalves, global health activist and epidemiologist at Yale, about the country’s history of public health unpreparedness, and what needs to happen to be ready for the next pandemic. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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