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Short Wave

The Closest Thing To A Cure For Allergies

09 Dec 2025

Transcription

Chapter 1: What is the main topic discussed in this episode?

0.031 - 19.052 Unknown

Thriving in the face of adversity, that's something the incredible species of our world do every day. I'm Chris Morgan. Join me on The Wild as we explore stories of hope and resilience in nature, and what they can teach us about ourselves and each other. Listen to The Wild from KUOW in Seattle, part of the NPR Network.

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20.483 - 39.488 Regina G. Barber

Hey, shortwavers. Real quick before the show, let's talk about public media. Public media has been in the news a lot this year. And public media is what makes NPR shows like Shortwave special. It's made for you. When you listen to an NPR podcast, the people who make it aren't thinking about shareholders or advertisers.

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40.048 - 58.663 Regina G. Barber

We're thinking about you and delivering on a promise to help you understand the world a little better. From its founding in the U.S., public media was always meant to tell stories from underrepresented communities, providing cultural insight that expands your perspective. At NPR, we still believe all of that. We always will.

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59.304 - 75.522 Regina G. Barber

But as of this fall, federal funding for public media, including NPR and local NPR stations, has been eliminated. And now we're heading into an uncharted future. But we know you won't let public media go away. We rely on your support to bring you Shortwave now more than ever.

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76.162 - 96.103 Regina G. Barber

This year, we have loved bringing you stories about what happens inside a top-secret nuclear facility, whether kids should be taking melatonin, why flowers are blooming early, how nightmares work, and what happens when AI cannibalizes its own data. And we can't wait to bring you more episodes like that in 2026.

Chapter 2: What are the common symptoms of allergies?

96.455 - 129.043 Regina G. Barber

So thank you if you already go the extra mile as an NPR Plus supporter. If not, you can join the Plus community. Get a bunch of perks like bonus episodes and more from across NPR podcasts. Support public media by signing up for NPR Plus today at plus.npr.org. You're listening to Shortwave from NPR. Hey short wavers, it's Regina Barber with a very important message. I hate allergies.

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129.732 - 151.825 Regina G. Barber

Itchy nose, runny eyes, when my throat gets scratchy. It's like my own body is rebelling against me. And it's not just seasonal allergies. My allergies can strike when I'm cleaning the house, when I'm mowing the lawn at any time of year, when I move to D.C. And after too many sneezes, I was like, it's time to take action. What is up with this?

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151.805 - 168.413 Dr. Gina Dapul-Hidalgo

So the idea behind allergies is that your body is overreacting to something harmless, right? So we're not supposed to be allergic to pollens, cats, dogs, foods, drugs. But if you are, your immune system encounters these allergens and it's thinking, danger, danger, when it's really something harmless.

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168.393 - 181.238 Regina G. Barber

That's Dr. Gina DePoole-Hidalgo. I invited her to the NPR studios because she's a pediatric and adult allergist in the D.C. suburbs. And she very patiently began our conversation with a recap of what allergies are.

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181.478 - 195.246 Dr. Gina Dapul-Hidalgo

You usually had to have been exposed to the allergen in the past. And it's that first exposure where your body ends up making allergic antibodies. what we call IgE or immunoglobulin E antibodies to those allergens.

195.587 - 208.575 Regina G. Barber

People's bodies have been doing this, encountering allergens, overreacting, creating these allergic antibodies for a long time, which means doctors have been trying to treat it for a long time.

208.555 - 227.408 Dr. Gina Dapul-Hidalgo

Most patients, we end up recommending things like antihistamines, nasal sprays, eye drops, really more symptomatic treatments to help decrease your symptoms so you can, you know, be around the allergen and be somewhat okay. Claritin, Zyrtec, Allegra, they're really temporary kinds of treatment options.

227.388 - 237.301 Regina G. Barber

But what if I told you there was another kind of treatment that worked for all but the most severe allergies? One that didn't just treat the symptoms of your allergies, but the actual cause of them.

237.481 - 256.365 Dr. Gina Dapul-Hidalgo

The idea is that you build tolerance over time. By giving you what you're allergic to, you get desensitized to those allergens that you're being treated with. Unlike medicines, which only take care of the symptoms, allergy shots are actually training your immune system to react differently when you're exposed to the allergens.

Chapter 3: How do allergies develop in the body?

696.171 - 701.46 Regina G. Barber

Like, am I cured? Like, do I have to do shot every month for the rest of my life or...

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701.44 - 711.198 Dr. Gina Dapul-Hidalgo

No. So this is something we get asked all the time. So the idea is that by getting to the maintenance dose, we recommend about a three to five year therapy.

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711.419 - 712.361 Regina G. Barber

Of just going once a month.

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712.521 - 718.552 Dr. Gina Dapul-Hidalgo

Yes. And there is no cure for allergies per se, which is why we can't say this is going to cure you.

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718.733 - 719.754 Regina G. Barber

I was telling everyone that.

719.915 - 735.993 Dr. Gina Dapul-Hidalgo

I'm like, these shots are going to cure me. And they're like, no. The closest thing to a cure. But in general, it's long lasting effect. And I have had some patients who did this years ago because, right, this has been out for over 100 years. Some that did this in their like middle elementary school.

736.053 - 752.721 Dr. Gina Dapul-Hidalgo

They'll come back to me in their 60s and say, oh, Dr. Gina, I want to start shots again because I feel like my symptoms have come back. So in that case, that was decades ago. of being asymptomatic to their allergen. So again, it's very individualized, which is why we can't say, oh, this will cure you.

752.821 - 759.898 Dr. Gina Dapul-Hidalgo

But really, the percentage that we really tell patients, it's anywhere from 80 to 90% effective for those who start shots.

759.878 - 768.392 Regina G. Barber

Okay. So, you know, I'm not asking for myself, just for a friend. Like, is there any side effects from these allergy shots that I've been taking?

Chapter 4: What are the traditional treatments for allergies?

883.471 - 890.159 Regina G. Barber

And I've noticed that the guidance has basically reversed since then in favor of the early introduction. Why did that change?

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890.199 - 904.136 Dr. Gina Dapul-Hidalgo

Yes. So it's exactly what you're saying, which is we didn't have it right. Right? So it was like 2008-ish. She was born in 2008. Yes. And the guidance back then was avoid the allergenic foods until age three.

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904.816 - 910.063 Regina G. Barber

And we're like, okay, we're going to avoid these allergenic foods. And then my Chinese mother just gave her everything and she was like, not even one.

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910.825 - 912.246 Regina G. Barber

And I was like, well, I guess she's fine.

912.347 - 937.272 Dr. Gina Dapul-Hidalgo

Yes. And so after those recommendations back then, we saw this huge prevalence of peanut allergy. And we're like, what is going on here? And then there was a game-changing study in 2015 that was actually about peanut allergy and high-risk patients and babies. And they found that by introducing peanut between four to six months of age, but definitely before one year of age,

937.252 - 951.078 Dr. Gina Dapul-Hidalgo

it actually decreased the incidence of peanut allergy in these high-risk kids. So after then, so now for a decade, we've been telling parents and, you know, advising our pediatrician colleagues, early introduction of allergenic foods, early introduction of allergenic foods.

Chapter 5: How do allergy shots work as a treatment?

951.218 - 958.251 Regina G. Barber

So my mom was right. Please don't tell her. Dr. Gina, thank you so much for talking to us today.

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958.652 - 960.475 Dr. Gina Dapul-Hidalgo

Thank you so much for having me, Regina.

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962.125 - 984.083 Regina G. Barber

If you like this show, we have done so many episodes on allergies. We'll link those episodes in the show notes. This episode was produced by Hannah Chin. It was edited by our showrunner, Rebecca Ramirez, and the facts were checked by Tyler Jones. Kwesi Lee was the audio engineer. Beth Donovan is our vice president of podcasting. I'm Regina Barber. Thank you for listening to Shorewave from NPR.

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