This week, Professor Luke O’Neill dives into one of the most remarkable stories in modern medicine: the birth of Hugo, the first child in the UK to be born from a womb transplanted from a deceased donor. His mother, Grace Bell, born without a womb due to MRKH syndrome, calls her baby son “simply a miracle.” Luke explores the incredible medical journey behind this milestone. The 10-hour womb transplant took place at The Churchill Hospital in Oxford in June 2024, followed by IVF treatment at The Lister Fertility Clinic in London. Consultant gynaecologist Professor Richard Smith, who has researched womb transplantation for over 25 years and was present at Hugo’s birth, was even honoured in Hugo’s full name. Beyond the headline-grabbing story, Luke takes listeners through the broader science of organ transplantation. He explains how immunosuppressant drugs revolutionised transplant success, looks at cutting-edge frontiers like 3D-printed organs and the potential use of animal organs, and considers the ongoing challenge of organ shortages. He also touches on Ireland’s organ waiting list, especially for kidneys, and the recent updates to donor rules.

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“What did the council decide on item 42?” — answered with the speaker and the moment.