Episode 265: DIY Hormone Therapy: When “Personalized” Goes Too Far

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Recorded13 Sep 2026

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Hormone therapy can be life-changing. Personalized care does not mean anything goes.In this episode, Dr. Carolyn Moyers explains why recreating a monthly bleed after menopause is not the same thing as restoring a menstrual cycle, why endometrial protection matters when systemic estrogen is used in a woman with a uterus, and what clinicians can consider when oral progesterone is not tolerated.She also takes a nuanced look at off-label vaginal use of 100- or 200-mg micronized progesterone capsules, what the evidence can and cannot tell us about endometrial protection, and why estrogen dose, progesterone dose, duration, bleeding, and follow-up all matter.One important distinction: none of this applies to recommended low-dose vaginal estrogen used for genitourinary syndrome of menopause. That is a different clinical situation, and it is generally not a reason to add a progestogen.This is not an anti-hormone episode. Dr. Moyers prescribes hormone therapy every day. It is an episode about what separates personalized medicine from experimentation.Related listening: Episode 253 — "The Hormone Question I Answer Multiple Times a Day: Progesterone vs Progestins."Important: This episode is educational and is not individualized medical advice. Do not start, stop, or change prescription hormone therapy based on a podcast. Postmenopausal bleeding should be discussed with a clinician and appropriately evaluated.🔗 Connect with Dr. Carolyn Moyers📸 Instagram: @drcarolynmoyers🎥 YouTube: @drcarolynmoyers🌐 Website: www.skywomenshealth.comWorld Menopause Day Event - get your ticketshttps://event.skywomenshealth.com/world-menopause-day-8703

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