π΄ Alex Karp LIVE from AIPCon 10 | Alex Karp, Peter Zaffino, Chad Wahlquist, Sam Berry
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What is discussed at the start of this section?
You're watching TBPN. Today is Thursday, June 4th, 2026. We are live from Palantir AIP Con with the Temple of Technology. It's back in LA. The Fortress of Finance. We will return to it, but it is also a state of mind. That's right. We are also sponsored by Rampant. Time is money. Save both. Easy to use corporate cards, bill pay, accounting, and a whole lot more all in one place. Big news from Ramp today. Massive fundraise. We're going to cover it in a little bit. But first, we've got to talk. Oh, is it still going? I like it. The Ramp song's back. This was early days. We really talked about Ramp so much. Turn it into a song. Anyway. uh the topic of conversation in dc has uh it's still in ai world but instead of talking about uh approving models before they're released today it's about the bio threat brandon gurel wrote in the tbp newsletter today the great houses of ai have united behind the bio threat there's actually a lot more to that because it was a big long list of signatories
from AI, but also from the bio world and biotech and even startups. We've seen former guests of the show sign on. I'm excited to bring some of those folks back on the show in the coming weeks and hear more about this because I have this belief that as AI advanced, we got cyber because it was such a tight feedback loop, such a tight verifiable reward. Reinforcement learning works really well in that context. Bio has some similar characteristics.
And it was a very tangible Y2K-style moment. Exactly. Where there was, let's just say, a powerful business strategy.
Yeah. It was like, is it over? You start thinking about the consequences of this. And you don't need to get to AGI, super intelligence god.
What are the implications of AI on national security?
You can just have a really powerful tool that creates a new problem. And that... creates full employment for Nikesh Varora over at Palo Alto Networks, who we had a chance to talk to yesterday. And he's been very fortunate in implementing the solutions to the cybersecurity threats posed by new AI systems, some of the new AI capabilities that are rolling out. But bio might be next, and so it's exciting to see that the great houses of AI are uniting behind the bio threat. Let's take you through this. First, I'm going to tell you about console.com. Console builds AI agents that automate 70% of IT, HR, and finance support, giving employees instant resolution for access requests and password resets. So in 1981, a group of researchers published the primary structure of the poliovirus genome in the journal Nature.
So they were basically open sourcing the sequence for making polio, which... just a few years earlier. Polio, I think, was on the decline by 1981, but a very, very problematic virus. It's an RNA virus, meaning that its nucleobases or building blocks are A, C, G, U, if you're familiar with RNA, adazine, cytosine, guanine, and uracil. Put more plainly, Thanks, Brandon Gorel. He says, when the researchers published the primary structure of the polio virus, they gave the world the literal sequence of polio virus building blocks in order from start to finish. By the mid-20th century, before mass vaccination, polio was paralyzing and killing more than half a million people per year worldwide. So you have this pretty deadly virus killing more than half a million people per year worldwide, and you have just open-sourced it.
What happens? So in 2002... researchers synthesized infectious poliovirus from its publicly available sequence data. So they didn't actually need any of the poliovirus RNA to start. They didn't need it on hand. It's not like they took a little sample and they just cloned it up and made it bigger. They just took the data and they made the actual virus. So this is the shape of the threat. If there's a new virus or an existing virus or a forgotten about virus and you have the code to it, you can potentially print that RNA. and then have the virus in your hands, even if you don't have a sample. You weren't able to collect a sample. So instead, these researchers in 2002, they were able to take the published sequence, chemically synthesize short DNA fragments, assemble them into a full-length DNA copy of the poliovirus genome, and then use the DNA to make the viral RNA to fully recover the infectious virus.
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Chapters
8 chapters
1
What is discussed at the start of this section?
0:00β1:38
2
What are the implications of AI on national security?
1:38β8:19
3
How is Palantir addressing the bio threat with AI?
8:19β16:14
4
What challenges does AI pose for government regulation?
16:14β47:53
5
What are the key insights shared by Peter Zaffino about AIG's operations?
47:53β50:20
6
How does Chad Wahlquist describe the integration of AI in problem-solving?
50:20β52:08
7
What technological advancements are highlighted by Sam Berry in the USDA?
52:08β59:00
8
How is data collection evolving in the context of USDA's initiatives?
59:00β1:49:37
Speakers
5 identifiedMore from TBPN
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