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TED Talks Daily

Could we detect breast cancer with a fingerprint? | Simona Francese

27 Aug 2025

Description

Breast cancer is the most common cancer among women globally. And yet, many people pass up opportunities to get screened for the disease, often because of the invasive and sometimes painful process of mammograms. Chemist and professor Simona Francese presents a potentially groundbreaking alternative that could transform how and when we identify this deadly disease.For a chance to give your own TED Talk, fill out the Idea Search Application: ted.com/ideasearch.Interested in learning more about upcoming TED events? Follow these links:TEDNext: ted.com/futureyouTEDSports: ted.com/sportsTEDAI Vienna: ted.com/ai-viennaTEDAI San Francisco: ted.com/ai-sf Hosted on Acast. See acast.com/privacy for more information.

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Transcription

Full Episode

6.038 - 28.617 Elise Hugh

You're listening to TED Talks Daily, where we bring you new ideas to spark your curiosity every day. I'm your host, Elise Hugh. According to the World Health Organization, breast cancer is the most common cancer in women globally. And yet many people ignore opportunities to get screened for early detection, whether it's because of lack of access or simple reluctance to get a mammogram.

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29.178 - 42.93 Elise Hugh

In her TEDx talk, chemist and professor Simona Francesi shares an unlikely but highly promising alternative to traditional cancer screenings that might revolutionize early detection. And it all starts with our fingerprints.

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48.175 - 84.161 Simona Francese

In this room, one in eight women will develop breast cancer, and one in 43 will die. Looks better for men, but they're not immune. And in 2022, the deaths by breast cancer were 670,000 globally, and 11,500 in the UK. That's 32 people every day. And cases are predicted to rise to 70,000 by 2040, right? But here's the good news.

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85.484 - 115.999 Simona Francese

The death rates are actually falling, and they've been falling remarkably, by 44 percent. Why? certainly because interventions and better screening and better treatments, but definitely because we can catch cancer earlier. So let's talk about screening, right? For breast cancer, we have the gold standard of mammography, which is followed by biopsy if the result is positive.

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117.397 - 142.527 Simona Francese

And we have the breast screening program that invites women every year after a certain age. But actually, the target is 70% nationally, but the uptake can be really low in some areas of the country. So why is that? We really need to understand the reasons why we can't do more screening and why we can't have a better uptake. Because I think we can.

143.468 - 166.81 Simona Francese

So, NHS backlogs, obviously this has been exacerbated by COVID, let me say, also by decades of underfunding of the NHS. We have reduced resources, so there is a disproportion between the number of screenings needed and the radiologists. Also, the mammographic equipment isn't exactly present in every city, town, village that you will need.

167.231 - 192.308 Simona Francese

So we have here an accessibility problem, which is significantly worse for underserved populations. Let's be honest, I personally would choose my life over my modesty, but this is not exactly an exam, a test that preserves your modesty, right? And for some populations, this is absolutely culturally unacceptable. It is invasive.

192.592 - 214.091 Simona Francese

there is a fear associated with radiation, and for many women, it's actually so painful that they refuse to go. There was a recent survey of 2,000 women, and a standard of 21 percent said that the embarrassment of being topless and the fear of pain would actually prevent them from undertaking screening.

215.434 - 215.494

OK.

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