The ONE Longevity Secret Primal and Blue Zones AGREE On with Mark Sisson

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Recorded13 Nov 2025

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He was a world-class athlete, trained harder than anyone, and followed the standard "healthy" high-carb diet... but by his mid-20s, Mark Sisson was secretly fighting arthritis, chronic digestive issues, and skin problems. What if the training and diet you believe is giving you a long life is actually making you sick? In this rare, candid discussion, the founder of Primal Kitchen, Mark Sisson, and Blue Zones expert Dan Buettner reveal the single biggest factor for longevity that both their radically different diets agree on, and it has nothing to do with food. You’ll discover the three most common mistakes that are making you metabolically doomed, the surprising business mistake that cost Sisson $1.5 million, and how he used one simple switch to achieve peak health and energy in his 70s. Tune in to learn the truth about metabolic flexibility and unlock the non-food genetic switches that can add decades of quality life.See omnystudio.com/listener for privacy information.

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