The Dr Pompa Podcast
Dr. Pompa Solo: Fixing Your Thyroid Won't Fix Your Thyroid (Fix This Instead)
31 Jan 2026
Chapter 1: What common symptoms indicate hormone resistance?
Do you have fatigue, anxiety, brain fog? Probably don't sleep great. Or even if you do sleep through the night, you just feel wiped out the next day. Can't make it through a day. You just don't have the energy. Or how about this? You walk into your closet and you go, what am I doing in here? What am I looking for? Or maybe it's any room for that matter. Okay.
Listen, that's happened to me, but there's an answer for that. And it's not what you think. And that's what this episode is about. How about this? What about a thyroid condition? Or maybe you think you have a thyroid condition, right? Your hair's thinning. Of course, my lack of energy. I can't even lose weight anymore. And even when I'm on a diet, I lose a little bit of weight, but it stops.
Or you fail on every diet because you start craving carbs and junk food, so you fail on every diet. Well, I'm going to tell you this. It's none of that's your fault, number one. And number two, again, repeating myself, there is a simple solution. Look, I think that many people would say,
Chapter 2: Why might fixing your thyroid not solve your health issues?
Look, you have a hormone problem, right? It's very in vogue right now to take hormones, right? Oh, you're in perimenopause or menopause and you just need to take estrogen or progesterone. There's a time and a place, but what I'm about to tell you is 95% of the time it's not needed and it doesn't give you a lasting solution anyway.
We have more people taking hormones, testosterone, estrogen regularly. you know, for different problems, right? Weight gain, feeling good about yourself, just feeling good in general, right? And it kind of works, but it's not a lasting solution. We have more people taking hormones, but it's not working out lasting or long term. There's a reason for that too.
And listen, I will say there is a time and a place. and i believe if you don't have an organ or a gland that produces a certain hormone because they took it out for some reason you probably need to take a hormone and even then sometimes people's condition is so deplorable that you need to take a hormone so i'm not against bioidentical hormones i'm not but i am also for the body producing its own
Lesson number one, there's nothing better than when your innate intelligence is keeping you in a perfect hormonal rhythm, meaning throughout the day, different stressors or demands, your body will raise up testosterone, lower testosterone, raise up cortisol, lower cortisol, raise up estrogen, progesterone. Meaning that there's this incredible balance that takes place constantly.
And you don't have to think about it, do you? Hopefully not. No, of course you don't. Because your innate intelligence does it as it needs it. There's a time for more hormones. There's a time for less hormones. Even as we age. Yes, estrogen, believe it or not, is meant to go down during menopause. You know why? It protects you from cancer and it actually allows you to live longer, healthier.
lower estrogen. But here's the problem. There's something pandemic in the United States of America in particular that is causing our cells not to hear hormones. And therefore, when the normal estrogen and hormones go down during menopause, and by the way, that's normal because most of your estrogen is produced in your adrenal glands after menopause, not from your ovaries like before menopause.
Okay, so the fact is, is that the body makes that shift of lower estrogen. But here's the cool thing. God knew what he was doing. Your cells become more sensitive to the estrogen in the progesterone, even though the levels are lower and we then feel normal. Do you know other countries? We look at menopause as something cherished, something celebrated, even for health and wisdom.
In a woman here, menopause is dreaded. So maybe it's not what we think. Would you agree with that? Maybe it's not about the lower estrogen. Maybe it's not as simple as that. Maybe it's what's blocking our cells from hearing estrogen. See, blood levels don't tell the whole story. This is important. Meaning hormones don't do their work in the blood. We just tend to measure them there.
do they do their work they do their work in the cell meaning once they attach to these little antennas receptors on our cells now they communicate within our cell and our dna and our mitochondria even some of the hormones enter the cell and they do all their magic and we stay lean we have energy our brain works no brain fog that's if the hormones actually get into the cell but what if
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Chapter 3: What is hormone resistance and how does it affect health?
This pandemic of something is blocking those hormones, stopping them, even damaging the receptors to them, and we can't hear the hormones. There's a scientific term for this, and it's called closed-door syndrome. Actually, no, that came later.
that means the hormones can't get into the cell the doors are closed it's called hormone resistance meaning that we're resisting the hormone you've heard of insulin resistance i'm sure right meaning you have plenty of insulin oftentimes too much insulin which causes damage and yet it's not getting its job done our cells are resistant so then glucose builds up in our cell instead of being being able to burn it up in our cells for energy that's a problem it's a disease we call diabetes but what about thyroid resistance
Meaning when people go to their doctor and say, my hair's thinning, I have no energy, brain fog, and I'm gaining weight all of a sudden. I must have a thyroid problem. And they go to their doctor, they measure their blood. And oftentimes they're said, no, your levels are normal. A little out of range. Ranges are so broad, but yeah, pretty normal. That was me, by the way. I had thinning hair.
I was gaining weight, what I called skinny fat. I had no energy and I had a lot of anxiety and other problems, but I knew my adrenals and thyroid weren't functioning well, but my blood work was always normal.
but how about this scenario because that's one right and then of course you go home frustrated because you don't have an answer but here's the other scenario you do go and you go oh your thyroid hormone is off blood range is off TSH is low or high something's wrong they give you a hormone and two months three months later you come back and wonderful news your blood levels are better and you say
Not so wonderful because I still can't lose weight. I still don't have energy. It was helped a little bit, but it seemed to help more. And now it's on. Okay, we'll just up your dose then. But your blood levels look so much better, but we'll give you a little more. That works for a little bit. And your blood levels are still in range. So all is well.
And you just go on life thinking, what is wrong? See, because no one ever told you that the cell, the hormones actually have to get into the cell to work. I'm going to draw it for you because I want you to understand this because this, enlightens us on potentially a different solution. And that's what I want you to get out of this, that there's a different solution. Can we hear me all right?
Okay, great. All right. So every cell, as I made the point, in our body, well, at least the cells that we're talking about here, have receptors on the cell. And the receptors actually are what the hormones have to attach to to get their message or themselves in here. It's like a cell phone, right?
You have a very expensive cell phone, and if you're taking hormones, very expensive hormone, but that cell phone's useless without a cell phone tower. Think of those receptors like that. It has to connect to that to get into the cell. Now, that could be thyroid, T3. It could be insulin. It could be estrogen, testosterone, progesterone.
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Chapter 4: How does inflammation impact hormone function?
Oh, here's how cool it is. As you gain fat cells on your body that we oftentimes don't like, well, guess what? It releases a hormone called leptin. You know what leptin does? Watch this. I'm going to draw a head. Leptin Oh gosh, that is a really bad person, but that's my person. Leptin goes to a place in the center of the brain, and it's called the pituitary hypothalamus.
There's receptors on the hypothalamus for leptin. You know what it does? As you gain fat cells down here, if I drew a belly down here,
as you gain fat cells you produce more leptin and that leptin tells the hypothalamus hey we're getting fat down here burn it and it burns it and we stay lean oh you know what else it does it tells you to slow down eating it controls your appetite it's not your fault told you it's not your fault because you know what many people have leptin resistance meaning the cells in your brain can't hear
the leptin hormone and so you don't go into a fat burning mode you don't get told to stop eating you crave carbohydrates because of your cells inability to use fat for energy so it makes you crave sugar you break every diet and oh by the way if you still are disciplined over that control mechanism guess what your body does for survival it breaks down your muscle into sugar
because your cell's inability to burn fat because of this hormone resistance, maybe at the brain, maybe at the cell, maybe it's thyroid, maybe it's leptin, maybe it's insulin, maybe it's testosterone, but it will absolutely just need sugar. It will break muscle down into sugar. It's called gluconeogenesis, but the more muscle you lose, now you get skinny fat. That's what happened to me.
And when you get skinny fat, your metabolism's low. You have no energy and you don't look good in mirrors. People think you're skinny, but you look at yourself in the mirror and you're sickened by it. That was me. But the fact is, is you're broken at the cell. You have closed-door syndrome. You have leptin resistance, insulin resistance, thyroid resistance. Okay, fact is this.
What can you do about it? That's the thing. The question I hope you thought about, what's causing the cellular inflammation? Because Dr. Pompa, if we could get to that, then wouldn't I hear my hormones better and not have to take all these hormones? Possibly, yes. Yes. That's the idea. If you get to the cause of something, the body has an ability to heal itself. It's true.
If you saw all of these testimonies out there of how I did Pampa's detox, I just tipped my hand, and how I got off my thyroid medication, I don't tell anyone to come off any medication or go on one. That's not the point here. I'm saying that there is a cause. And if you remove the cause, the body can do it. And your body can, yes, it wouldn't need to lean on a hormone in that case.
And you can't just stop hormones or meds not making that recommendation because now your body's not producing it. One of the problems with taking hormones, your body stops producing its own and now you end up in a new problem. These hormones, when you take them, constant levels, you're not getting the fluctuations that innate intelligence likes to do in a day.
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Chapter 5: What are the main causes of cellular inflammation?
I chased my adrenal problem for many years because of all the fatigue and anxiety and sleep problems. But the fact was, it was here. I had too much mercury driving massive inflammation.
and then it was throwing off the whole system and of course that inflamed also the cells of my body so then i was blocking other hormones i had no sex drive and i was young and nothing worked the way it should because my cells weren't hearing my hormones so what if we get to that cause maybe yours is a moldy home
Maybe yours is a hidden infection in the jaw, unknowing, where you got a wisdom tooth pulled and it heals over. No pain, but infections there. Oh, it drives cellular inflammation. What if you have parasites and don't know it? What if you have, and I could keep going, what if you have a buildup of other heavy metals like lead and arsenic? Oh, where does that start? In utero.
You know where most of my mercury came from? My mom, she had silver fillings. There's a study called the DRASH study. It was one of the first studies to show the number of silver fillings in mom's mouth
is proportional to how much mercury they found in the baby's brain on autopsy studies yeah that's where mine study that's where mine started and if i would have well i don't want to say died but if i did and they was in that study they would have found a lot of mercury in my pituitary hypothalamus and that was a problem but you know what my wife had major lead levels you know where she got it from her mom because they grew up in the lead generation in utero a lot of lead is stored in the bone during pregnancy it's very normal to lose bone because of estrogen shifts normal but out comes the lead
into the baby in utero oh and then we get our other exposures through life don't we right i had so my own silver fillings put in i wore contact lenses in the 70s 80s early 90s it had mercury thimerosal right in the saline solution oh of course i went through a time where i was eating a lot of big fish tuna because i wanted to be healthy gained a lot of mercury there oh my mother used aluminum foil constantly in everything that we did oh gained a lot of aluminum and thank god i didn't have a lot of vaccines but think about kids today
where they're using aluminum as an adjunct to make the vaccine actually work. Mercury too. So these accumulations happen throughout our life until one day the bucket overflows and that's when we get the diagnosis or the symptoms start. Then the thyroid condition and we're chasing thyroid, chasing hormones, when all of those things I just said are driving cellular inflammation.
But if we deal correctly, 20 years of teaching doctors this, if we deal with those exposures that have accumulated over our lifetime and one day the symptoms start and we think that it started then, If I had thought it started when I was 30 years old, I was wrong. It started way before that, even though I didn't have symptoms before that.
But that accumulation, and now we're affected by plastics that accumulate, persistent toxins like forever chemicals that are in all the personal care products, shampoos, all of these things are accumulating in our tissues. How possibly can we expect to have normal hormone function or brain function?
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Chapter 6: How can detoxing the cell improve hormone sensitivity?
You can learn and do it yourself. Believe me, you can learn it. You can do it. I have a program that teaches people this. 20 years of teaching doctors, you know, it was my oldest son that said, Dad, take it to people. Teach people how to do it. People looking for an answer, just like you are. How are we going to do that? Social media.
Yeah, as an old guy, I never had a concept that we could take a message directly, people looking for an answer. That's what I've done because of my son Daniel's encouragement. But yeah, that's my passion.
my purpose if we can fix and up regulate all those pathways that determine how the cell detoxes you get your life back your hormones work again that's how you down regulate the inflammation there's specific toxins we even have i i have tests that we do and i i think in the training they'll add in i talk about the test but um it is literally pathways or certain symptoms even that we know get compromised and create certain symptoms i should say
that will tell us what toxins people have been exposed to. You know, a lot of people who don't feel well, they're actually living in moldy homes, unknowing to them, and they always say, I got my home tested, okay, I talk about that. They do have hidden infections. I talked a little bit about these cavitations that can form.
They have heavy metal exposures, and where the metals accumulate will determine certain symptoms, but all of that is testable. And if you get to that, and you get to these inflammatory causes, you have a lasting solution. And you're not spending all this wasted money on a lot of different drugs and who knows what other solutions. I know I tried it all. I was the guy who tried it all.
Most things fail. But I'm going to end here. I know in my heart of hearts, God showed me everything. From Pain to Purpose is actually the name of this podcast, right? For a reason. Because it was my pain that gave me the purpose of how I even sit here today. But there's one word that's not there that is our family mantra, from pain to purpose to promise. And this is a true story.
My wife, when I was sick and looking for an answer, it massively disrupted our entire family and everything in my life. Life as I know it literally came to a screeching halt. But many times she was on her knees praying for me and the family at this particular time. God spoke to her heart that not only was he going to get me well, but I'm going to take a message to the world.
And by the way, when she would say that to me, I'd get very angry. My exact words were, I can't even get myself well. How dare you put that on me? I didn't see it, but that promise, pain to purpose to promise, got her through. And what I found out even just recently is my two oldest sons, that's what got them through.
They said, Dad, we would hear mom talk about God has a purpose and what God told her. And they hung on to that promise too, believe it or not. It wasn't until many years later that I was like, she was right or God was right through her. that all of that God showed me to be here with an answer.
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