Fertility Inc.: The Embryo Editing Dinner

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The Journal. 23 min 4 speakers 3 chapters transcribed 5 months ago
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What is the main topic discussed in this episode?

Jess 0:00
Hey, it's Jess.
Ryan Knudson 0:01
And Ryan. Tickets for our live show in Los Angeles are on sale now.
Jess 0:06
Join us Tuesday, April 28th at the El Rey Theater at 8 p.m. There'll be special guests, conversations about the business of Hollywood, and afterwards, we'll stick around to meet you all.
Ryan Knudson 0:16
Find a link in our show notes to get your tickets before they sell out, which they did very quickly last time.
Unknown 0:21
See you there!
Emily Glazer 0:29
Let's travel back to the summer. It's late July. We're in the Bay Area in San Francisco at this ultra luxury restaurant called Quince.
Ryan Knudson 0:44
Our colleague Emily Glazer is describing a dinner she learned about a while ago. She talked to some of the people who were there.
Emily Glazer 0:50
There was a whole group of Silicon Valley elite and scientists that were in a private room at the back of this restaurant, which had vintage Finnish furniture.
Ryan Knudson 1:04
At the center of the group was the evening's host.
Emily Glazer 1:07
Brian Armstrong is there, wearing all black, kind of holding court.
Ryan Knudson 1:14
Brian Armstrong is the billionaire co-founder and CEO of Coinbase. the US's biggest crypto company.
Emily Glazer 1:22
And the evening kicked off with a central question for the attendees. How might they bring the powerful and highly debated medical technology known as embryo editing to fruition?
Ryan Knudson 1:40
Embryo editing. Going into an embryo and tweaking its DNA. In other words, genetically engineering a baby. This was the idea that was on the table that night, along with the farm-to-table cuisine.
Emily Glazer 1:58
It was basically called the embryo editing dinner.
Ryan Knudson 2:01
It was called the embryo editing dinner?
Emily Glazer 2:03
Yes. Well, a calendar invite that I reviewed that went out to attendees described as embryo editing dinner.
Ryan Knudson 2:10
We asked Brian Armstrong for an interview, but through a representative, he declined. But the topic of the conversation, to be clear, was should we edit an embryo or can we edit an embryo?

What is the embryo editing dinner and who was involved?

Emily Glazer 2:26
You know what? It was actually neither of those. It was we are going to edit an embryo.
Ryan Knudson 2:35
So one more big picture question before we dig into the details. What's at stake here?
Emily Glazer 2:43
Life as we know it?
Ryan Knudson 2:48
Welcome to The Journal, our show about money, business, and power. I'm Ryan Knudson. It's Friday, March 27th.
Ryan Knudson 3:05
Coming up, one final story from the fringes of the fertility industry. And this one is very fringe. Today, Silicon Valley's quest to genetically engineer a baby
Ryan Knudson 3:33
When it comes to reproductive technology, we are on the threshold of a new frontier. Today's gene editing techniques allow scientists to cut, edit, and insert DNA with remarkable precision. It's now possible to rewrite a child's genetic code before they're even born. But while this has been technically possible for a while now, it's only known to have been done once, by one scientist.
Unknown 3:59
A Chinese researcher has shaken the international science community. He claims to have created the world's first genetically edited babies.
Emily Glazer 4:09
There is a Chinese scientist named He Zhenkui, who in 2018 claimed to have done embryo editing. He shocked the world with this news that he had produced children genetically altered as embryos to be immune to HIV.
Unknown 4:29
The embryos were then implanted into the mother, and Lulu and Nana were born earlier this month.
Emily Glazer 4:37
As you perhaps could imagine, there were a lot of people that were very upset about this for a wide variety of reasons.
Ryan Knudson 4:45
prominent scientists denounced He.
Unknown 4:48
I mean, I think it's very disturbing. It's inappropriate. It goes against all of the guidelines that were established.
Ryan Knudson 4:54
He Jinghui was sentenced to three years in prison by Chinese authorities. And today, many scientists and doctors remain convinced that embryo editing is not ready to unleash on the world.
Emily Glazer 5:06
As recently as 2025, there was this whole coalition of scientists, biotech companies, patient advocates that called for a 10-year moratorium on trying to bring an edited embryo to term unless there's a whole global regulatory framework and consensus on ethical and safety issues.
Ryan Knudson 5:28
Why are people concerned about this technology?
Emily Glazer 5:31
All right, there's a bunch of things at play here. Number one is what could pass on to future generations?
Ryan Knudson 5:38
When you edit an embryo, it changes that person's DNA.

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