Alcoholism is a scourge on modern society. Every year, 178,000 American die from alcohol abuse, and it has been estimated that over 200 billion dollars is lost from the US economy due to alcoholism, includingcosts of health care, lost productivity, and costs of crime enforcement. Given this immense social cost, it is equally amazing that there is no widely accepted cure. Rather, alcoholics are told they need to abstain from taking a single drink for the rest of their lives, or they are likely to revert to their earlier states of alcohol abuse. Katie Herzog is a journalist whose work I have enjoyed and I was happy to have a conversation with her in general. But even more so after the publication of her recent book, Drink your Way Sober. She discusses there a fascinating science-based approach that appears to provide a ‘cure’ for many alcoholics that actually allows them to drink, if they wish, in moderation, for the rest of their lives. The idea is to use an opioid blocker, in this case something called naltrexone, that basically removes the pleasure response from drinking. A naltrexone pill can be taken a few hours before drinking, and over time, with the correct behavioral management, it has been shown to be effective for many drinking in removing the craving for alcohol.What makes Katie’s book, and our discussion, so poignant is that Katie is not just a journalist writing about alcoholism, she was an alcoholic for most of her life, and her discovery of the work of of the so-called Sinclair Method, after the scientist David Sinclair, whose original work on naltrexone in Finland changed the field, changed her life. Her book intersperses her own experiences with the science underlying this new treatment for alcoholism, and it is thus perfect for our podcast, which connects science and culture. It also makes for a fascinating and informative conversation that I hope will help have a positive impact on treating this international blight. I hope you find it engrossing and as enjoyable to listen to as it was to produce.And there are still berths available on our Greece and Cyprus adventure. Go to originsproject.org and explore the possibilities!As always, an ad-free video version of this podcast is also available to paid Critical Mass subscribers. Your subscriptions support the non-profit Origins Project Foundation, which produces the podcast. The audio version is available free on the Critical Mass site and on all podcast sites, and the video version will also be available on the Origins Project YouTube. Get full access to Critical Mass at lawrencekrauss.substack.com/subscribe

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