Tucker Debates Biotech CEO on Baby Customization, Eugenics, and God’s Existence

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The Tucker Carlson Show 1h 38m 3 speakers 8 chapters transcribed 2 months ago
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What is the role of Kian Sadeghi and Nucleus Genomics?

Tucker Carlson 0:04
Thanks for doing this. I appreciate it. I'll just say at the outset, which I told you off camera, I disagree with this conceptually, I think, but I'm also completely ignorant of the details. Yeah. So I kind of want to know what this is before even asking you questions about whether it's a good idea. Can you just, I'll just stand back and let you explain what you're doing.
Kian Sadeghi 0:25
Yeah, so first, thanks for having me on. Of course. So patients, there's one way of reproducing via IVF, right? So you can conceive naturally via sex or maybe if you're infertile or if you have some sort of hereditary disease or for some other reason, you do IVF. When you do, yeah.
Tucker Carlson 0:41
I'm sorry, I specialize in dumb questions. Can you just explain for people who don't know What is IVF? Yeah, what is IVF?
Kian Sadeghi 0:46
IVF stands for in vitro fertilization. So basically imagine the egg and the sperm, right? The foundation of life to make an embryo. It's basically putting those things together in a clinic, right? And then basically you take that embryo and you transfer it into a woman and then an implant and the woman's pregnant. So conception takes place outside the womb. Correct. Okay. Yeah. And so during this process of IVF, what you do is today, even if nucleus didn't exist, even if genetic optimization didn't exist, you make several embryos. Okay. So in your IVF clinic, you make several embryos. The amount of embryos you end up making, it varies, but you might have four or five. You actually do genetic testing on these embryos to identify things like chromosome abnormalities, like Down syndrome, for example.
Kian Sadeghi 1:28
So that's very commonplace. That's done in basically every IVF clinic in the United States. They will actually screen embryos, the genetics of the embryos, to see if they have some sort of severe chromosomal abnormality. What we do is we basically provide more information on the embryos. So we also read the DNA, but now we give information on things like other hereditary disease risk, also chronic diseases, things like cancers, Alzheimer's, diabetes, also traits like IQ or height, et cetera. So to be clear, we're not changing any DNA. There's this process in IVF where you make embryos already. Genetic testing is done in embryos. What we do now is we provide you a little bit more information on your embryos.
Kian Sadeghi 2:06
So basically that information can be used, then implant which embryo the couple deems to be best. So basically give more information to couples to then choose which embryo they want to implant.
Tucker Carlson 2:16
I don't want to derail this conversation two minutes in. Okay. But you just said we can tell the IQ of a person by the genetics? So IQ... I was reliably informed IQ is not real, okay? And it's not determined by genetics.

What is IVF and how does it work?

Kian Sadeghi 2:31
So I think it's helpful to think about all these different characteristics from diseases to traits, right? People know intuitively something like height, for example, right? Height, they say, oh, that's genetic. Or something like breast cancer. Eye color. these things people intuitively know are genetic. And so you can actually basically take these different phenotypes and measure how genetic any phenotype is. So what does it actually mean? The most simple way of explaining it is imagine you took two identical twins, so they have the same DNA, right? And then basically you separated the twins, they grew up in different environments. Sometimes in pop culture, people hear about these different things where you actually take twins and they have, again, the same DNA, their identical DNA.
Kian Sadeghi 3:08
And then they grow up in different places for whatever reason. So they're subject to different environments. And then you can actually measure basically how much more similar they, how similar they are across all these different phenotypes to see basically how genetic something is. Twin studies. Yes, twin studies. Yes. And so using twin studies, you can actually get measurements of things from diseases, like cancers and diabetes and Alzheimer's, as mentioned, to things like height or IQ or BMI, et cetera. So twin studies show that IQ specifically is about 50% genetic.

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