Episode 312 People have been given genetically engineered microbes to prevent a common health condition - and it worked. The gut microbiome is now known to be associated with many health conditions - and in this case, the team managed to treat 9 people who get recurring kidney stones. With the gut’s links to mental health, cancer and more, could engineered microbes be used to treat more conditions in the future? Is 1.5C dead? It’s looking increasingly likely that we’re going to breach 1.5C of global warming - the goal set out in the Paris agreement. So do we need to set a new goal now? As scientists come up with alternative numbers to aim for, many are worried that moving the goalposts will kill climate ambition. But is there a middle ground that keeps everyone happy? Where are all the aliens? We may now have a solution to the famous Fermi paradox, which questions why we’ve never met anyone else in the universe, despite the existence of many Earth-like planets. And it’s all to do with tectonic plates - a geological phenomenon that may be rare outside of Earth, helping complex life to emerge on our planet. Chapters: (00:39) Genetically modified gut microbes (07:03) Setting a new goal for global warming (17:20) Solving the Fermi paradox Hosted by Rowan Hooper and Penny Sarchet, with guests Grace Wade, Madeleine Cuff, Alex Wilkins, Ilana Seid, Robert Stern and Taras Gerya. To read more about these stories, visit https://www.newscientist.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices

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“What did the council decide on item 42?” — answered with the speaker and the moment.