Thrive on Plants

#46 - Weight Loss vs Weight Maintenance: Lessons from 10,000 People Who Kept It Off

14 Jan 2026

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Weight loss and weight maintenance are not the same skill set, and treating them as if they are is one of the biggest reasons so many people lose weight only to regain it. In this episode of the Thrive on Plants Podcast, Dr. Daphne Bascom sits down with Dr. Holly Wyatt and Dr. James Hill to unpack what actually changes in your body, brain, and environment when you lose weight, why maintenance is harder, and how to build a plant‑powered life that supports long‑term success at any age.IN THIS EPISODE, WE COVER:Why GLP‑1 medications (like semaglutide and similar drugs) work so well for weight loss, and why stopping them often triggers rapid regain if you do not have a maintenance plan in place.The difference between weight loss and weight maintenance, including how metabolic adaptation, set point, and muscle loss can work against you, especially in midlife.The 3 pillars of long‑term success: food (resetting appetite naturally on a whole‑food, plant‑based pattern), movement (how much and what kind protects weight loss and muscle), and mindstate (the daily mental “state” that separates short‑term success from sustainable change).How perimenopause and menopause change metabolism, body composition, and appetite signals, and what midlife women can do to protect lean mass and metabolic health with or without GLP‑1s.The three maintenance profiles (food seeker, sedentary sitter, setback cycler) and how to tailor your strategy based on where you see yourself.If you want to learn how to stop weight-loss meds without regaining, this conversation offers evidence‑based, compassionate guidance you can put into practice today.ResourcesDr. Holly Wyatt & Dr. James HillBook, “Losing the Weight Loss Meds”: https://www.amazon.com/dp/1637747802?ref=ppx_yo2ov_dt_b_fed_asin_titleWebsite: https://www.weightlossand.com/Website: https://www.weightwisdom.com/“Weight Loss and…” podcast on Apple: https://podcasts.apple.com/us/podcast/weight-loss-and/id1723878862Key research referenced:SURMOUNT‑4 trial on stopping meds and cardiometabolic health: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2841273Additional resources to help you thrive on plants: 🌱 Join our free Thrive on Plants community: Join Here 🌱 Access the free Plant-Powered Body course: Access Here 🌱 Take the free health assessment for women 40+: Start Here 🌱 Watch every episode on YouTube ⭐️ If you loved this episode, please leave a review! ⭐️ Here’s how to do it on Apple Podcasts: Go to the Thrive on Plants Podcast page: Click here Scroll down to the ‘Ratings & Reviews’ section. Tap ‘Write a Review’ (you may be prompted to log in with your Apple ID). Thank you for your support!

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13:00H | 21 DIC 2025 | Fin de Semana

01 Jan 1970

Fin de Semana

10:00H | 21 DIC 2025 | Fin de Semana

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12:00H | 20 DIC 2025 | Fin de Semana

01 Jan 1970

Fin de Semana

2ª PARTE | 06 ENE 2026 | EL PARTIDAZO DE COPE

01 Jan 1970

El Partidazo de COPE

3ª PARTE | 22 ENE 2026 | EL PARTIDAZO DE COPE

01 Jan 1970

El Partidazo de COPE

3ª PARTE | 04 MAR 2026 | EL PARTIDAZO DE COPE

01 Jan 1970

El Partidazo de COPE

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Thrive on Plants

#46 - Weight Loss vs Weight Maintenance: Lessons from 10,000 People Who Kept It Off

This episode hasn't been transcribed yet

Other recent transcribed episodes

13:00H | 21 DIC 2025 | Fin de Semana

10:00H | 21 DIC 2025 | Fin de Semana

12:00H | 20 DIC 2025 | Fin de Semana

2ª PARTE | 06 ENE 2026 | EL PARTIDAZO DE COPE

3ª PARTE | 22 ENE 2026 | EL PARTIDAZO DE COPE

3ª PARTE | 04 MAR 2026 | EL PARTIDAZO DE COPE

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