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Greetings, Earthlings: Philip Johnston of Starcloud on Data Centers in Space

17 Mar 2026

Contributed by Lukas

Philip Johnston, founder and CEO of Starcloud, explains why space will become the primary location for AI compute infrastructure within the next decad...

Physics Gets a Vote: Nominal Cofounders on Hardware Development in an AI World

10 Mar 2026

Contributed by Lukas

Nominal’s cofounders (Cameron McCord, Jason Hoch and Bryce Strauss) realized that the new age of reindustrialization requires a new approach to hard...

Building the GitHub for RL Environments: Prime Intellect's Will Brown & Johannes Hagemann

10 Feb 2026

Contributed by Lukas

Will Brown and Johannes Hagemann of Prime Intellect discuss the shift from static prompting to "environment-based" AI development, and their Environme...

What’s the Future of Vertical SaaS in an AGI World? Jamie Cuffe, CEO of Pace

03 Feb 2026

Contributed by Lukas

Jamie Cuffe is solving one of AI's hardest problems: getting conservative, regulated industries to trust autonomous agents with mission-critical work....

Making the Case for the Terminal as AI's Workbench: Warp’s Zach Lloyd

27 Jan 2026

Contributed by Lukas

Zach Lloyd built Warp to modernize the terminal for professional developers, but the rise of coding agents transformed his company's trajectory. He di...

Context Engineering Our Way to Long-Horizon AI: LangChain’s Harrison Chase

21 Jan 2026

Contributed by Lukas

Harrison Chase, cofounder of LangChain and pioneer of AI agent frameworks, discusses the emergence of long-horizon agents that can work autonomously f...

How Ricursive Intelligence’s Founders are Using AI to Shape The Future of Chip Design

14 Jan 2026

Contributed by Lukas

Anna Goldie and Azalia Mirhoseini created AlphaChip at Google, using AI to design four generations of TPUs and reducing chip floor planning from month...

Training General Robots for Any Task: Physical Intelligence’s Karol Hausman and Tobi Springenberg

06 Jan 2026

Contributed by Lukas

Physical Intelligence’s Karol Hausman and Tobi Springenberg believe that robotics has been held back not by hardware limitations, but by an intellig...

Why the Next AI Revolution Will Happen Off-Screen: Samsara CEO Sanjit Biswas

16 Dec 2025

Contributed by Lukas

Sanjit Biswas is one of the rare founders who has scaled AI in the physical world – first with Meraki, and now with Samsara, a $20B+ public company ...

The Rise of Generative Media: fal's Bet on Video, Infrastructure, and Speed

10 Dec 2025

Contributed by Lukas

fal is building the infrastructure layer for the generative media boom. In this episode, founders Gorkem Yurtseven, Burkay Gur, and Head of Engineerin...

Why IDEs Won't Die in the Age of AI Coding: Zed Founder Nathan Sobo

02 Dec 2025

Contributed by Lukas

Nathan Sobo has spent nearly two decades pursuing one goal: building an IDE that combines the power of full-featured tools like JetBrains with the res...

How End-to-End Learning Created Autonomous Driving 2.0: Wayve CEO Alex Kendall

18 Nov 2025

Contributed by Lukas

Alex Kendall founded Wayve in 2017 with a contrarian vision: replace the hand-engineered autonomous vehicle stack with end-to-end deep learning. While...

How Google’s Nano Banana Achieved Breakthrough Character Consistency

11 Nov 2025

Contributed by Lukas

When Google launched Nano Banana, it instantly became a global phenomenon, introducing an image model that finally made it possible for people to see ...

OpenAI Sora 2 Team: How Generative Video Will Unlock Creativity and World Models

06 Nov 2025

Contributed by Lukas

The OpenAI Sora 2 team (Bill Peebles, Thomas Dimson, Rohan Sahai) discuss how they compressed filmmaking from months to days, enabling anyone to creat...

Nvidia CTO Michael Kagan: Scaling Beyond Moore's Law to Million-GPU Clusters

28 Oct 2025

Contributed by Lukas

Recorded live at Sequoia’s Europe100 event: Michael Kagan, co-founder of Mellanox and CTO of Nvidia, explains how the $7 billion Mellanox acquisitio...

Securing the AI Frontier: Irregular Co-founder Dan Lahav

21 Oct 2025

Contributed by Lukas

Irregular co-founder Dan Lahav is redefining what cybersecurity means in the age of autonomous AI. Working closely with OpenAI, Anthropic, and Google ...

Why AI Will Transform Customer Experience: Cresta CEO Ping Wu and Sequoia’s Doug Leone

14 Oct 2025

Contributed by Lukas

Ping Wu built Google's contact center business before becoming CEO of Cresta, where he's pioneering a unique approach to contact center transformation...

Block CTO Dhanji Prasanna: Building the AI-First Enterprise with Goose, their Open Source Agent

30 Sep 2025

Contributed by Lukas

As CTO of Block, Dhanji Prasanna has overseen a dramatic enterprise AI transformation, with engineers saving 8-10 hours a week through AI automation. ...

Why Businesses Are Rejecting the AI They’ve Asked For: Agency CEO Elias Torres

23 Sep 2025

Contributed by Lukas

Elias Torres has been building AI systems since 1999, from chatbots at IBM to co-founding Drift and now Agency. He believes businesses are caught in a...

Building the "App Store" for Robots: Hugging Face's Thomas Wolf on Physical AI

09 Sep 2025

Contributed by Lukas

Thomas Wolf, co-founder and Chief Science Officer of Hugging Face, explains how his company is applying the same community-driven approach that made t...

Deal Velocity, Not Billable Hours: How Crosby Uses AI to Redefine Legal Contracting

02 Sep 2025

Contributed by Lukas

Ryan Daniels and John Sarihan are reimagining legal services by building Crosby, an AI-powered law firm that focuses on contract negotiations to start...

n8n CEO Jan Oberhauser on Building the Universal AI Automation Layer

26 Aug 2025

Contributed by Lukas

When the AI wave hit, n8n founder Jan Oberhauser faced a critical choice: become irrelevant or become indispensable. He chose the latter, transforming...

Scaling the ‘Cursor for Slides’ to $50M ARR: Gamma founder Jon Noronha

19 Aug 2025

Contributed by Lukas

Before ChatGPT made AI mainstream, John Noronha was building Gamma with a simple insight: everyone hates making slides but needs visual communication ...

Delphi’s Dara Ladjevardian: How AI Digital Minds Can Scale Human Connection

12 Aug 2025

Contributed by Lukas

Dara Ladjevardian, founder and CEO of Delphi, is creating digital minds that allow people to scale their thoughts and availability without replacing h...

Vercel CEO Guillermo Rauch: Building the Generative Web with AI

05 Aug 2025

Contributed by Lukas

Vercel CEO Guillermo Rauch has spent years obsessing over reducing the friction between having an idea and getting it online. Now with AI, he's achiev...

OpenAI’s IMO Team on Why Models Are Finally Solving Elite-Level Math

30 Jul 2025

Contributed by Lukas

In just two months, a scrappy three-person team at OpenAI sprinted to fulfill what the entire AI field has been chasing for years—gold-level perform...

OpenAI Just Released ChatGPT Agent, Its Most Powerful Agent Yet

22 Jul 2025

Contributed by Lukas

Isa Fulford, Casey Chu, and Edward Sun from OpenAI's ChatGPT agent team reveal how they combined Deep Research and Operator into a single, powerful AI...

DeepMind's Pushmeet Kohli on AI's Scientific Revolution

11 Jul 2025

Contributed by Lukas

Pushmeet Kohli leads AI for Science at DeepMind, where his team has created AlphaEvolve, an AI system that discovers entirely new algorithms and prove...

Mapping the Mind of a Neural Net: Goodfire’s Eric Ho on the Future of Interpretability

08 Jul 2025

Contributed by Lukas

Eric Ho is building Goodfire to solve one of AI’s most critical challenges: understanding what’s actually happening inside neural networks. His te...

ElevenLabs’ Mati Staniszewski: Why Voice Will Be the Fundamental Interface for Tech

01 Jul 2025

Contributed by Lukas

Mati Staniszewski, co-founder and CEO of ElevenLabs, explains how staying laser-focused on audio innovation has allowed his company to thrive despite ...

From DevOps ‘Heart Attacks’ to AI-Powered Diagnostics With Traversal’s AI Agents

24 Jun 2025

Contributed by Lukas

Anish Agarwal and Raj Agrawal, co-founders of Traversal, are transforming how enterprises handle critical system failures. Their AI agents can perform...

The Breakthroughs Needed for AGI Have Already Been Made: OpenAI Former Research Head Bob McGrew

17 Jun 2025

Contributed by Lukas

As OpenAI's former Head of Research, Bob McGrew witnessed the company's evolution from GPT-3’s breakthrough to today's reasoning models. He argues t...

OpenAI Codex Team: From Coding Autocomplete to Asynchronous Autonomous Agents

10 Jun 2025

Contributed by Lukas

Hanson Wang and Alexander Embiricos from OpenAI's Codex team discuss their latest AI coding agent that works independently in its own environment for ...

Google I/O Afterparty: The Future of Human-AI Collaboration, From Veo to Mariner

03 Jun 2025

Contributed by Lukas

Fresh off impressive releases at Google’s I/O event, three Google Labs leaders explain how they’re reimagining creative tools and productivity wor...

From Data Centers to Dyson Spheres: P-1 AI's Path to Hardware Engineering AGI

27 May 2025

Contributed by Lukas

Former Airbus CTO Paul Eremenko shares his vision for bringing AI to physical engineering, starting with Archie—an AI agent that works alongside hum...

Gong’s Amit Bendov: From Meeting Recordings to Revenue AI

20 May 2025

Contributed by Lukas

CEO Amit Bendov shares how Gong evolved from a meeting transcription tool to an AI-powered revenue platform that's increasing sales capacity by up to ...

LIVE: Google's Jeff Dean on the Coming Transformations in AI

16 May 2025

Contributed by Lukas

At AI Ascent 2025, Jeff Dean makes bold predictions. Discover how the pioneer behind Google's TPUs and foundational AI research sees the technology ev...

LIVE: Ambient Agents and the New Agent Inbox ft. Harrison Chase of LangChain

15 May 2025

Contributed by Lukas

Recorded live at Sequoia’s AI Ascent 2025: LangChain CEO Harrison Chase introduces the concept of ambient agents, AI systems that operate continuous...

LIVE: How AI is Reinventing Software Business Models ft. Bret Taylor of Sierra

14 May 2025

Contributed by Lukas

Recorded live at Sequoia’s AI Ascent 2025: Sierra co-founder Bret Taylor discusses why AI is driving a fundamental shift from subscription-based pri...

LIVE: Sam Altman of OpenAI on Building the ‘Core AI Subscription’ for Your Life

14 May 2025

Contributed by Lukas

Recorded live at Sequoia’s AI Ascent 2025: Sam reflects on OpenAI’s evolution from a 14-person research lab to a dominant AI platform. He envision...

Workday CEO Carl Eschenbach: Building the System of Record for the AI Era

06 May 2025

Contributed by Lukas

Workday CEO and Sequoia partner Carl Eschenbach explains how the company is evolving its platform to handle both human and AI workers. He shares Workd...

The Quest to ‘Solve All Diseases’ with AI: Isomorphic Labs’ Max Jaderberg

29 Apr 2025

Contributed by Lukas

After pioneering reinforcement learning breakthroughs at DeepMind with Capture the Flag and AlphaStar, Max Jaderberg aims to revolutionize drug discov...

Pricing in the AI Era: From Inputs to Outcomes, with Paid CEO Manny Medina

22 Apr 2025

Contributed by Lukas

Former Outreach CEO Manny Medina discusses his new company Paid, which provides billing, pricing and margin management tools for AI companies. He expl...

Arc Institute's Patrick Hsu on Building an App Store for Biology with AI

15 Apr 2025

Contributed by Lukas

Patrick Hsu, co-founder of Arc Institute, discusses the opportunities for AI in biology beyond just drug development, and how Evo 2, their new biology...

Replit CEO Amjad Masad on 1 Billion Developers: A Better End State than AGI?

08 Apr 2025

Contributed by Lukas

Amjad Masad set out more than a decade ago to pursue the dream of unleashing 1B software creators around the world. With millions of Replit users pre-...

Why CRM Needs an AI Revolution, with Day.ai Founder Christopher O’Donnell

01 Apr 2025

Contributed by Lukas

Christopher O’Donnell believes the fundamental problems with CRM—incomplete data, complex workflows, siloed work products and the fear of leads fa...

From Software Engineers to AI Word Artisans: Filip Kozera of Wordware

25 Mar 2025

Contributed by Lukas

Filip Kozera sees parallels between Excel’s democratization of data analytics and Wordware’s mission to put AI development in the hands of knowled...

Josh Woodward: Google Labs is Rapidly Building AI Products from 0-to-1

18 Mar 2025

Contributed by Lukas

As VP of Google Labs, Josh Woodward leads teams exploring the frontiers of AI applications. He shares insights on their rapid development process, why...

How AI Breakout Harvey is Transforming Legal Services, with CEO Winston Weinberg

11 Mar 2025

Contributed by Lukas

Harvey CEO Winston Weinberg explains why success in legal AI requires more than just model capabilities—it demands deep process expertise that doesn...

The AI Product Going Viral With Doctors: OpenEvidence, with CEO Daniel Nadler

04 Mar 2025

Contributed by Lukas

OpenEvidence is transforming how doctors access medical knowledge at the point of care, from the biggest medical establishments to small practices ser...

OpenAI’s Deep Research Team on Why Reinforcement Learning is the Future for AI Agents

25 Feb 2025

Contributed by Lukas

OpenAI’s Isa Fulford and Josh Tobin discuss how the company’s newest agent, Deep Research, represents a breakthrough in AI research capabilities b...

Palo Alto Networks’ Nikesh Arora: AI, Security and the New World Order

18 Feb 2025

Contributed by Lukas

Palo Alto Networks’s CEO Nikesh Arora dispels DeepSeek hype by detailing all of the guardrails enterprises need to have in place to give AI agents “...

MongoDB’s Sahir Azam: Vector Databases and the Data Structure of AI

13 Feb 2025

Contributed by Lukas

MongoDB product leader Sahir Azam explains how vector databases have evolved from semantic search to become the essential memory and state layer for A...

Roblox Studio Head Stef Corazza: Using AI to Empower Creators

04 Feb 2025

Contributed by Lukas

Stef Corazza leads generative AI development at Roblox after previously building Adobe’s 3D and AR platforms. His technical expertise, combined with...

ReflectionAI Founder Ioannis Antonoglou: From AlphaGo to AGI

28 Jan 2025

Contributed by Lukas

Ioannis Antonoglou, founding engineer at DeepMind and co-founder of ReflectionAI, has seen the triumphs of reinforcement learning firsthand. From Alph...

Kumo’s Hema Raghavan: Turning Graph AI into ROI

21 Jan 2025

Contributed by Lukas

Hema Raghavan is co-founder of Kumo, a company that makes graph neural networks accessible to enterprises by connecting to their relational data store...

Databricks Founder Ion Stoica: Turning Academic Open Source into Startup Success

14 Jan 2025

Contributed by Lukas

Berkeley professor Ion Stoica, co-founder of Databricks and Anyscale, transformed the open source projects Spark and Ray into successful AI infrastruc...

XBOW CEO and GitHub Copilot Creator Oege de Moor: Cracking the Code on Offensive Security With AI

10 Dec 2024

Contributed by Lukas

Oege de Moor, the creator of GitHub Copilot, discusses how XBOW’s AI offensive security system matches and even outperforms top human penetration te...

Ramp CEO Eric Glyman: Using AI to Build “Self-Driving Money”

03 Dec 2024

Contributed by Lukas

When ChatGPT ushered in a new paradigm of AI in everyday use, many companies attempted to adapt to the new paradigm by rushing to add chat interfaces ...

Dust’s Gabriel Hubert and Stanislas Polu: Getting the Most From AI With Multiple Custom Agents

26 Nov 2024

Contributed by Lukas

Founded in early 2023 after spending years at Stripe and OpenAI, Gabriel Hubert and Stanislas Polu started Dust with the view that one model will not ...

Clay’s Kareem Amin on Building the Sales ‘System of Action’ with AI

19 Nov 2024

Contributed by Lukas

Clay is leveraging AI to help go-to-market teams unleash creativity and be more effective in their work, powering custom workflows for everything from...

Decart’s Dean Leitersdorf on AI-Generated Video Games and Worlds

13 Nov 2024

Contributed by Lukas

Can GenAI allow us to connect our imagination to what we see on our screens? Decart’s Dean Leitersdorf believes it can. In this episode, Dean Leite...

How Glean CEO Arvind Jain Solved the Enterprise Search Problem – and What It Means for AI at Work

29 Oct 2024

Contributed by Lukas

Years before co-founding Glean, Arvind was an early Google employee who helped design the search algorithm. Today, Glean is building search and work a...

OpenAI Researcher Dan Roberts on What Physics Can Teach Us About AI

22 Oct 2024

Contributed by Lukas

In recent years there’s been an influx of theoretical physicists into the leading AI labs. Do they have unique capabilities suited to studying large...

Google NotebookLM’s Raiza Martin and Jason Spielman on Creating Delightful AI Podcast Hosts and the Potential for Source-Grounded AI

15 Oct 2024

Contributed by Lukas

NotebookLM from Google Labs has become the breakout viral AI product of the year. The feature that catapulted it to viral fame is Audio Overview, whic...

Snowflake CEO Sridhar Ramaswamy on Using Data to Create Simple, Reliable AI for Businesses

08 Oct 2024

Contributed by Lukas

All of us as consumers have felt the magic of ChatGPT—but also the occasional errors and hallucinations that make off-the-shelf language models prob...

OpenAI's Noam Brown, Ilge Akkaya and Hunter Lightman on o1 and Teaching LLMs to Reason Better

02 Oct 2024

Contributed by Lukas

Combining LLMs with AlphaGo-style deep reinforcement learning has been a holy grail for many leading AI labs, and with o1 (aka Strawberry) we are seei...

Why Vlad Tenev and Tudor Achim of Harmonic Think AI Is About to Change Math—and Why It Matters

24 Sep 2024

Contributed by Lukas

Adding code to LLM training data is a known method of improving a model’s reasoning skills. But wouldn’t math, the basis of all reasoning, be even...

Jim Fan on Nvidia’s Embodied AI Lab and Jensen Huang’s Prediction that All Robots will be Autonomous

17 Sep 2024

Contributed by Lukas

AI researcher Jim Fan has had a charmed career. He was OpenAI’s first intern before he did his PhD at Stanford with “godmother of AI,” Fei-Fei L...

Founder Eric Steinberger on Magic’s Counterintuitive Approach to Pursuing AGI

10 Sep 2024

Contributed by Lukas

There’s a new archetype in Silicon Valley, the AI researcher turned founder. Instead of tinkering in a garage they write papers that earn them the r...

Crucible Moments Returns for S2: The ServiceNow Story ft. CEO Frank Slootman & Founder Fred Luddy

03 Sep 2024

Contributed by Lukas

On Training Data, we learn from innovators pushing forward the frontier of AI’s capabilities. Today we’re bringing you something different. It’s...

Sierra Co-Founder Clay Bavor on Making Customer-Facing AI Agents Delightful

27 Aug 2024

Contributed by Lukas

Customer service is hands down the first killer app of generative AI for businesses. The reasons are simple: the costs of existing solutions are so hi...

Phaidra’s Jim Gao on Building the Fourth Industrial Revolution with Reinforcement Learning

20 Aug 2024

Contributed by Lukas

After AlphaGo beat Lee Sedol, a young mechanical engineer at Google thought of another game reinforcement learning could win: energy optimization at d...

Fireworks Founder Lin Qiao on How Fast Inference and Small Models Will Benefit Businesses

13 Aug 2024

Contributed by Lukas

In the first wave of the generative AI revolution, startups and enterprises built on top of the best closed-source models available, mostly from OpenA...

GitHub CEO Thomas Dohmke on Building Copilot, and the the Future of Software Development

06 Aug 2024

Contributed by Lukas

GithHub invented collaborative coding and in the process changed how open source projects, startups and eventually enterprises write code. GitHub Copi...

Meta’s Joe Spisak on Llama 3.1 405B and the Democratization of Frontier Models

30 Jul 2024

Contributed by Lukas

As head of Product Management for Generative AI at Meta, Joe Spisak leads the team behind Llama, which just released the new 3.1 405B model. We spoke ...

Klarna CEO Sebastian Siemiatkowski on Getting AI to Do the Work of 700 Customer Service Reps

23 Jul 2024

Contributed by Lukas

In February, Sebastian Siemiatkowski boldly announced that Klarna’s new OpenAI-powered assistant handled two thirds of the Swedish fintech’s custo...

Reflection AI’s Misha Laskin on the AlphaGo Moment for LLMs

16 Jul 2024

Contributed by Lukas

LLMs are democratizing digital intelligence, but we’re all waiting for AI agents to take this to the next level by planning tasks and executing acti...

Microsoft CTO Kevin Scott on How Far Scaling Laws Will Extend

09 Jul 2024

Contributed by Lukas

The current LLM era is the result of scaling the size of models in successive waves (and the compute to train them). It is also the result of better-t...

Zapier’s Mike Knoop launches ARC Prize to Jumpstart New Ideas for AGI

02 Jul 2024

Contributed by Lukas

As impressive as LLMs are, the growing consensus is that language, scale and compute won’t get us to AGI. Although many AI benchmarks have quickly a...

Factory’s Matan Grinberg and Eno Reyes Unleash the Droids on Software Development

25 Jun 2024

Contributed by Lukas

Archimedes said that with a large enough lever, you can move the world. For decades, software engineering has been that lever. And now, AI is compound...

LangChain’s Harrison Chase on Building the Orchestration Layer for AI Agents

18 Jun 2024

Contributed by Lukas

Last year, AutoGPT and Baby AGI captured our imaginations—agents quickly became the buzzword of the day…and then things went quiet. AutoGPT and Ba...

Introducing "Training Data"

05 Jun 2024

Contributed by Lukas

Join us as we train our neural nets on the theme of the century: AI. Sequoia Capital partners Sonya Huang and Pat Grady host conversations with leadin...