Dr. John Wigneswaran—Dr. Wig—Chief Clinical Officer for Optum Rx at UnitedHealth Group, joins host Dr. Michael Anderson to discuss leading pharmacy and clinical strategy at enterprise scale. From early lessons in a community pediatric practice to C-suite roles at Walmart and Optum, Dr. Wig shares how mentorship, feedback, and self-awareness propelled his leadership journey. He details how physician executives can align patient advocacy with business priorities—“never compromise patient care”—and outlines a practical approach to managing change across complex organizations. The discussion dives into the near-term impact of AI on member experience, operational efficiency, and drug trend forecasting, along with the promise of dynamic, individualized formularies. Optimistic about the next decade, Dr. Wig calls for affordability, access, and kindness to guide transformation.

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