Menu
Sign In Search Podcasts Charts People & Topics Add Podcast API Pricing

Anna Greka

👤 Person
316 total appearances

Appearances Over Time

Podcast Appearances

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

But it is an unlikely story and one that I feel still very lucky and blessed to have had these opportunities.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

So for sure, it's been...

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

Ah, yes.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

This is interesting.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

And actually, I encourage more colleagues to think about it this way.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

So I have always been driven by the science.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

And I think that it seems a little backward to some people.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

But I did my PhD in neuroscience because I was interested

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

in understanding something about these ion channels that were newly discovered at the time.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

They were most highly expressed in the brain.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

Here I was doing work in the brain in the neuroscience program at Harvard.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

But then once I completed my PhD and I was in the middle of my residency training, actually, at Mass General, I distinctly remember that there was a paper that came out that implicated the same family of ion channels that I had spent my time understanding in the brain.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

It turned out to be a channelopathy that causes kidney disease.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

So that was the light bulb.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

And, you know, it made, you know, it made me realize that maybe what I really wanted to do is just like follow this thread.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

And like my scientific curiosity basically led me into studying the kidney.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

And then it seemed practical, therefore, to get done with my clinical training as efficiently as possible.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

So I finished residency, I did nephrology training.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

And then there I was in the lab, like trying to understand what,

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

you know, the biology around this channelopathy.