Anné Verhoef

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178 appearances 1 recordings 1 series first heard Mar 2026 last heard 11 Mar

Anné Verhoef’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 1 in all, peaking in Mar 2026 with 1.

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The Last Show with David Cooper · FULL EPISODE: AI and Why Self-Awareness Never Hurts - March 10, 2026 · 11 Mar 2026 podcast

Yeah, that's a great question.

So far, we have treated across different cancer sites that we've treated patients in different clinical trials.

I can tell you that we've treated over 100 cancer patients.

And what one you may call the biomarker or hint that we have that this works is that the patients who can take this and keep it in their microbiome over time, that means their microbiome becomes like the donor microbiome, they do tend to do better.

In the initial study that we published in Nature Medicine in melanoma patients that's a deadly form of skin cancer a couple of years ago, we showed that there are certain characteristics in the patients that we are still studying that actually determines if they can be a host that can keep the donor microbiome.

It's like, if you will, that the kidney transplant is not getting rejected.

So one of them...

was that if they're alpha diversity, that means the shape of their microbiome was actually more diseased than normal, believe it or not.

And the reason for that, we think, is that when somebody's microbiome is actually less healthy, it's easier to change it.

So we have good evidence in the CD4 as well, rather than somebody's microbiome who's healthy.

You look pretty healthy, so it might be more difficult to change your microbiome.

Yeah, that's a great question.

And that's something that we are working on right now.

We are building two randomized clinical trials, one in melanoma in 128 patients in Canada.

And we just got funded to do the largest FMT trial with healthy donor poop in lung cancer, 160 patients.

And hopefully, when that's positive, we can go to the FDA and Health Canada and make it available to everybody else.

Thanks, David.

I really appreciate having me.

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