Arthur C. Brooks
speaker
1,407 appearances
1 recordings
1 series
first heard Jul 2026
last heard 9 Jul
Arthur C. Brooks’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 1 in all, peaking in Jul 2026 with 1.
Appearances
Rumination per se, everything in neuroscience is contested because it's such a new field.
So I try to stay away from any research that hasn't been replicated.
If it's too new, I don't generally write about it.
I don't generally talk about it in my column or write about it in my research because I want it to be replicable, but still everything's legitimately contested, especially neuroscience because it's a new field.
30 years ago, almost no universities had neuroscience departments, and now they all do because this is the black box.
This is the thing that we really all want to understand, but it's still a black box.
That said, rumination, which involves, according to really pretty good and provocative research, a part of the brain called the ventrolateral prefrontal cortex, VLPFC for short,
And it's not just about ruminative sadness, which has probably evolved so that you can solve problems and don't make the same mistake twice.
Like, uh, I made a mistake.
I'm so stupid.
Or you make it over and over and over.
Yeah, yeah.
Or you can get into a maladaptive cycle, which is why when you raise serotonin in the synapse, it lowers activity, ruminative activity in the ventrolateral prefrontal cortex.
Here's the unintended secondary.
If you raise?
If you raise serotonin.
So if you take a serotonin,
a selective serotonin reuptake inhibitor, Prozac.
What it does is it leaves more serotonin in the synapse of the brain, and that's correlated with less activity in the ventral lateral prefrontal cortex, according to a lot of these studies.
I haven't seen it because I haven't done fMRI studies on this myself.
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