Benjamin Thompson
speaker
746 appearances
10 recordings
1 series
first heard Jul 2026
last heard 2 Sep
Benjamin Thompson’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 10 in all, peaking in Jul 2026 with 5.
Appearances
One limitation is the lack of direct markers of DNA repair.
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Even DNA damage can't be easily measured in a meaningful way across organ systems in people, she says.
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VIG's team focuses on mutations because they are a major consequence of DNA damage.
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Except for large structural variations, mutations are pretty easy to quantify.
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But mutations alone don't seem to explain aging.
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My great frustration is that we cannot really demonstrate that accumulating mutations in cells make them sick, says Vic.
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The only example is cancer, he says, in which it is a reasonable assumption, given that mutations accumulate with age and cause cancer.
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But what about heart disease?
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What about neurodegeneration?
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It's likely that for some conditions, the signaling that accompanies DNA damage is more important than the damage or mutations themselves, says Scheibik Nerson.
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But what types of DNA damage are most responsible for the problematic signalling, why some damage seems to persist without being fixed, and how that damage accumulates with age remain big question.
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Yeah.
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Ultimately, what's most relevant for aging might differ from tissue to tissue, making it a long shot to attempt to treat it in just one way.
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Robbins, who has been pursuing ways to kill or neutralize senescent cells for more than a decade, predicts that the field will progress as researchers identify small ways to enhance health span, and then find synergy among those smaller effects.
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Still, he says if enough people are testing drugs and looking at this, you just never know what home run you are going to get.
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End quote.
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To read more of nature's long-form journalism, head over to nature.com slash news.
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Nature Podcast · Highest-ever ocean temperatures recorded as El Niño intensifies · 26 Aug 2026
podcast
had no idea.
But now the data's I find this not only refreshing but but at some level astounding.
Nature.
Showing 121–140 of 746 · page 7 of 38
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