Bonnie Bassler

speaker

763 appearances 1 recordings 1 series first heard Jul 2026 last heard 20 Jul

Bonnie Bassler’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 1 in all, peaking in Jul 2026 with 1.

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Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas · 361 | Bonnie Bassler on How Bacteria Talk and Work Together · 20 Jul 2026 podcast

And so synchronizing these behaviors where I get the benefit of your work, you get the benefit of my work,

Because we're doing it as a collective, we get that's very common in pathogenic bacteria and in beneficial bacteria.

And I guess I should do one plug for your...

Listeners who I know are very sophisticated and like science for the sake of science.

You know, there's a real industrial, biomedical, agricultural part to this, right?

Which is scientists have now learned about quorum sensing, good or bad, right?

So if we can beef up quorum sensing in beneficial bacteria, either in humans or animals,

industry or agriculture or we can interfere with quorum sensing in these harmful bacteria right those are applications that are being made now based on you know learning about these crazy bioluminescent bacteria really that started this right and now there's a very there's many many people scientists working on these applications you know based on what we've learned

Right.

So I do want to make a little plug that we're not just playing in our sandbox.

Yeah.

So we've made molecules that look like

the quorum-sensing autoinducers, but they're what are called antagonists, right?

So they're inhibitors.

So they slot into the receptors, but they block.

the real molecules, right?

And those shut down virulence in animal models, right?

These aren't in real medicine yet, but in our labs, right, if we either make bacteria that just can't do quorum sensing or we make synthetic strategies to shut down quorum sensing, make them so they can't make the autoinducers, make them so the receptors get blocked, they have their entire

repertoire of virulence factors intact.

It's command and control.

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