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Bryan Johnson

👤 Person
1440 total appearances

Appearances Over Time

Podcast Appearances

On Purpose with Jay Shetty
Bryan Johnson: New SHOCKING Science on How to Reverse Your Age by 31 Years & The Damaging Impact of 1 Bad Night Sleep

it really is in chasing the cumulative measurement across the entire body. For example, like I'm the most, I've spent more time in an MRI than anyone in the world. I think this new technology called DNA methylation, you're looking at these patterns in the body. I'm the most measured person with that DNA methylation in the world. And so like,

On Purpose with Jay Shetty
Bryan Johnson: New SHOCKING Science on How to Reverse Your Age by 31 Years & The Damaging Impact of 1 Bad Night Sleep

it really is in chasing the cumulative measurement across the entire body. For example, like I'm the most, I've spent more time in an MRI than anyone in the world. I think this new technology called DNA methylation, you're looking at these patterns in the body. I'm the most measured person with that DNA methylation in the world. And so like,

On Purpose with Jay Shetty
Bryan Johnson: New SHOCKING Science on How to Reverse Your Age by 31 Years & The Damaging Impact of 1 Bad Night Sleep

Doing this consistently, routinely, we do thousands of data points a week. And so I think it's just all these things adding up. It's just expensive to do the test, analyze the data, continually have that process. We need a large team to do it.

On Purpose with Jay Shetty
Bryan Johnson: New SHOCKING Science on How to Reverse Your Age by 31 Years & The Damaging Impact of 1 Bad Night Sleep

Doing this consistently, routinely, we do thousands of data points a week. And so I think it's just all these things adding up. It's just expensive to do the test, analyze the data, continually have that process. We need a large team to do it.

On Purpose with Jay Shetty
Bryan Johnson: New SHOCKING Science on How to Reverse Your Age by 31 Years & The Damaging Impact of 1 Bad Night Sleep

Yeah, MRI we think is very safe. But CT, I've only done once. I just did a calcium score. And then we do blood draws. I've done a ton of blood work. We did ultrasound on my veins a while back to see if we had scar tissue that had been building up because I've done so much blood draw. We couldn't find any scar tissue.

On Purpose with Jay Shetty
Bryan Johnson: New SHOCKING Science on How to Reverse Your Age by 31 Years & The Damaging Impact of 1 Bad Night Sleep

Yeah, MRI we think is very safe. But CT, I've only done once. I just did a calcium score. And then we do blood draws. I've done a ton of blood work. We did ultrasound on my veins a while back to see if we had scar tissue that had been building up because I've done so much blood draw. We couldn't find any scar tissue.

On Purpose with Jay Shetty
Bryan Johnson: New SHOCKING Science on How to Reverse Your Age by 31 Years & The Damaging Impact of 1 Bad Night Sleep

So we do actively measure for negative repercussions of are we measuring too much to the extent of damage? So we're even measuring the measurement. So in every way we can possibly interrogate the body, we're trying to acquire data.

On Purpose with Jay Shetty
Bryan Johnson: New SHOCKING Science on How to Reverse Your Age by 31 Years & The Damaging Impact of 1 Bad Night Sleep

So we do actively measure for negative repercussions of are we measuring too much to the extent of damage? So we're even measuring the measurement. So in every way we can possibly interrogate the body, we're trying to acquire data.

On Purpose with Jay Shetty
Bryan Johnson: New SHOCKING Science on How to Reverse Your Age by 31 Years & The Damaging Impact of 1 Bad Night Sleep

We looked at every organ. So if you, we have roughly 70 plus organs, depending on how you count. And so you can say like, I'm chronologically 47 years old, but that's not really a useful number. It's like a general approximation. Then if you measure the heart, you can say, okay, what is the biological age of the heart? And you can then dissect that and say, what is the structural age of the heart?

On Purpose with Jay Shetty
Bryan Johnson: New SHOCKING Science on How to Reverse Your Age by 31 Years & The Damaging Impact of 1 Bad Night Sleep

We looked at every organ. So if you, we have roughly 70 plus organs, depending on how you count. And so you can say like, I'm chronologically 47 years old, but that's not really a useful number. It's like a general approximation. Then if you measure the heart, you can say, okay, what is the biological age of the heart? And you can then dissect that and say, what is the structural age of the heart?

On Purpose with Jay Shetty
Bryan Johnson: New SHOCKING Science on How to Reverse Your Age by 31 Years & The Damaging Impact of 1 Bad Night Sleep

And then what is the functional age of the heart? Like you can look at the functional age of like, what is the max heart rate? You know, you can take 220 minus your age roughly for a rough calculation. Then you look at the valves and you look at all the cell types. And so you can break each organ down into different ways to understand what is its biological age.

On Purpose with Jay Shetty
Bryan Johnson: New SHOCKING Science on How to Reverse Your Age by 31 Years & The Damaging Impact of 1 Bad Night Sleep

And then what is the functional age of the heart? Like you can look at the functional age of like, what is the max heart rate? You know, you can take 220 minus your age roughly for a rough calculation. Then you look at the valves and you look at all the cell types. And so you can break each organ down into different ways to understand what is its biological age.

On Purpose with Jay Shetty
Bryan Johnson: New SHOCKING Science on How to Reverse Your Age by 31 Years & The Damaging Impact of 1 Bad Night Sleep

So for example, like my heart is 37. My left ear is 64. My diaphragm is age 18. And so you can any part of the body, any organ or biological process, you can assign an age score if you've got data to show, data to make that comparison.

On Purpose with Jay Shetty
Bryan Johnson: New SHOCKING Science on How to Reverse Your Age by 31 Years & The Damaging Impact of 1 Bad Night Sleep

So for example, like my heart is 37. My left ear is 64. My diaphragm is age 18. And so you can any part of the body, any organ or biological process, you can assign an age score if you've got data to show, data to make that comparison.

On Purpose with Jay Shetty
Bryan Johnson: New SHOCKING Science on How to Reverse Your Age by 31 Years & The Damaging Impact of 1 Bad Night Sleep

Yeah.

On Purpose with Jay Shetty
Bryan Johnson: New SHOCKING Science on How to Reverse Your Age by 31 Years & The Damaging Impact of 1 Bad Night Sleep

Yeah.

On Purpose with Jay Shetty
Bryan Johnson: New SHOCKING Science on How to Reverse Your Age by 31 Years & The Damaging Impact of 1 Bad Night Sleep

I shot a lot of guns as a kid. And so I would, you know, aim the gun like this with this left ear exposed sound, this, this, it was more protected and then also loud music. And so, yeah, so this is the thing is like now when I'm at social events, I have this app on my phone decibel where like last night I was at a social event and the room was 105 decibels.

On Purpose with Jay Shetty
Bryan Johnson: New SHOCKING Science on How to Reverse Your Age by 31 Years & The Damaging Impact of 1 Bad Night Sleep

I shot a lot of guns as a kid. And so I would, you know, aim the gun like this with this left ear exposed sound, this, this, it was more protected and then also loud music. And so, yeah, so this is the thing is like now when I'm at social events, I have this app on my phone decibel where like last night I was at a social event and the room was 105 decibels.

On Purpose with Jay Shetty
Bryan Johnson: New SHOCKING Science on How to Reverse Your Age by 31 Years & The Damaging Impact of 1 Bad Night Sleep

So anything over 80 can cause hearing damage. So just in a social environment with people talking in a voice that's like loud enough for the other person to hear, you've got sustained ear hearing damage.

On Purpose with Jay Shetty
Bryan Johnson: New SHOCKING Science on How to Reverse Your Age by 31 Years & The Damaging Impact of 1 Bad Night Sleep

So anything over 80 can cause hearing damage. So just in a social environment with people talking in a voice that's like loud enough for the other person to hear, you've got sustained ear hearing damage.