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Carl Hennigan

👤 Person
978 total appearances

Appearances Over Time

Podcast Appearances

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

There's been a lot of stress about we've got a lockdown.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

Some people are not performing and doing what they should.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

They're going out too often or they're meeting in groups.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

Therefore, the next step is to have a permanent lockdown where you stop people exercising.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

And we've looked at the evidence for this.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

And there's a Cochrane review that's been updated.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

There's an observational study.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

It's very clear that

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

exercise is good for you in terms of your general health and in terms of preventing comorbidities so that's established therefore we don't want people to stop exercising do it but the problem is when you start to look at it in acute respiratory infections there are some trials but they're underpowered they tend to show you the actually a direction of trend that it reduces the duration of illness

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

However, this is a perfect opportunity to do them studies in areas like in France where they're saying no exercise.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

You could actually go, we're going to do some trials here.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

We're going to actually do the work and the research that we need.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

But the problem is when you go to the trial register, it's all about drugs, all about in vivo studies.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

It's all about prediction rules, diagnostics, very few studies on non-drug interventions.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

So right now we need people to switch on and go, where's the behavioural interventions?

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

Where's these interventions where we can test some of these issues?

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

Let's get on with it.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

The problem is the clock's ticking.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

It will take time to set them up and we may have missed the boat again.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

And Carl.